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Antidiabetics
VILDAGET-M-50MG/500MG
SALT COMPOSITION
VILDAGLIPTIN 50MG + METFORMIN 500MGTYPE
TABLET
STORAGE
Store below 25°C in a dry place, protected from light and moisture. Keep out of reach of children.
PRODUCT INTRODUCTION
VILDAGET-M-50MG/500MG is a powerful combination medication designed for the management of Type 2 Diabetes Mellitus in adults. This tablet combines Vildagliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor, with Metformin, a biguanide, to offer comprehensive blood sugar control. It works by targeting multiple pathways involved in glucose regulation, helping patients achieve better glycemic targets. VILDAGET-M is a crucial tool in preventing the long-term complications associated with uncontrolled high blood sugar, making it a valuable option for diabetic patients in India.
Uses of VILDAGET-M-50MG/500MG
VILDAGET-M-50MG/500MG is prescribed to improve glycemic control in adults with Type 2 Diabetes Mellitus.
- Type 2 Diabetes Mellitus
This medication is used as an adjunct to diet and exercise to improve blood sugar control in adults with Type 2 Diabetes. It is particularly beneficial when diet and exercise alone, or Metformin monotherapy, do not provide adequate glycemic control. The combination helps to lower both fasting and post-meal blood glucose levels, reducing the risk of diabetes-related complications.
- Glycemic Control Enhancement
VILDAGET-M is indicated for patients who require additional glycemic control beyond what can be achieved with a single antidiabetic agent. By combining two different classes of drugs, it addresses multiple aspects of glucose dysregulation, making it an effective choice for patients struggling to maintain target blood sugar levels. It helps in achieving HbA1c goals more effectively.
- Prevention of Complications
Effective management of Type 2 Diabetes with medications like VILDAGET-M can significantly reduce the risk of developing serious long-term complications. These include cardiovascular diseases, kidney damage (nephropathy), nerve damage (neuropathy), and eye problems (retinopathy). Consistent blood sugar control is vital for a better quality of life and preventing disease progression.
Side Effects of VILDAGET-M-50MG/500MG
Like all medicines, VILDAGET-M-50MG/500MG can cause side effects, although not everybody gets them. Most side effects are mild to moderate and temporary.
Common side effects
- Nausea
- Diarrhea
- Abdominal pain
- Headache
- Dizziness
Serious but rare side effects can occur and require immediate medical attention.
- Lactic acidosis (rare but serious complication of Metformin)
- Pancreatitis (inflammation of the pancreas)
- Liver problems (hepatitis, abnormal liver function tests)
If any side effect bothers you or persists, please consult your doctor. Do not stop taking the medication without medical advice.
How to use VILDAGET-M-50MG/500MG
- Adults:
The usual recommended dose of VILDAGET-M-50MG/500MG is one tablet orally, once or twice daily, preferably with meals to reduce gastrointestinal side effects. The dosage should be individualized based on the patient's current treatment regimen, effectiveness, and tolerability, as advised by a healthcare professional. Do not exceed the maximum recommended daily dose.
- Children:
VILDAGET-M-50MG/500MG is not recommended for use in children and adolescents below 18 years of age due to insufficient data on safety and efficacy in this population. Pediatric dosing guidelines have not been established for this combination medication.
- Elderly:
No dose adjustment is typically required based on age alone. However, as elderly patients are more likely to have decreased renal function, kidney function should be assessed before initiating treatment with Metformin-containing products and monitored regularly. Use with caution in elderly patients with pre-existing renal impairment.
- Missed Dose:
If you miss a dose of VILDAGET-M-50MG/500MG, take it as soon as you remember, unless it is almost time for your next dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. Consult your doctor if you are unsure.
How VILDAGET-M-50MG/500MG works
VILDAGET-M-50MG/500MG leverages the synergistic actions of its two active components. Vildagliptin enhances the body's natural ability to lower high blood glucose levels. It does this by inhibiting the enzyme DPP-4, which normally breaks down incretin hormones like GLP-1 and GIP. By preserving these incretins, Vildagliptin increases insulin secretion from the pancreas when blood glucose levels are high and reduces glucagon secretion, thereby decreasing hepatic glucose production. Metformin, on the other hand, primarily works by decreasing glucose production by the liver and improving insulin sensitivity in peripheral tissues, such as muscles, allowing them to absorb glucose more effectively. It also delays the absorption of glucose from the intestines. Together, Vildagliptin and Metformin provide a complementary mechanism of action, leading to more robust and sustained reductions in blood glucose levels, helping patients manage their Type 2 Diabetes effectively.
Precautions
- Monitor kidney function regularly, especially before starting treatment and periodically thereafter, due to the Metformin component.
- Avoid excessive alcohol intake while on this medication, as it can increase the risk of lactic acidosis.
- Inform your doctor if you have a history of pancreatitis or liver disease.
- Discontinue VILDAGET-M temporarily before any surgical procedure or imaging tests involving iodinated contrast agents.
- Be aware of symptoms of hypoglycemia (low blood sugar), especially when combined with other antidiabetic agents.
- Report any unexplained muscle pain, nausea, vomiting, or rapid breathing, as these could be signs of lactic acidosis.
Safety Advice
Alcohol
UNSAFEConsumption of alcohol while taking VILDAGET-M-50MG/500MG is unsafe. Alcohol can increase the risk of lactic acidosis, a rare but serious side effect of Metformin, and may also affect blood sugar levels.
Pregnancy
CONSULT YOUR DOCTORVILDAGET-M-50MG/500MG is generally not recommended during pregnancy. Consult your doctor if you are pregnant, planning to become pregnant, or suspect you might be pregnant, as they will assess the risks and benefits.
Breastfeeding
CONSULT YOUR DOCTORIt is unknown if Vildagliptin passes into breast milk, while Metformin is known to be excreted in small amounts. Therefore, VILDAGET-M-50MG/500MG should be used with caution during breastfeeding. Discuss with your doctor.
Driving
CAUTIONVILDAGET-M-50MG/500MG generally does not cause hypoglycemia when used alone. However, if used in combination with other antidiabetic agents, it may cause dizziness or low blood sugar, which could affect your ability to drive or operate machinery. Exercise caution.
Kidney
CAUTIONVILDAGET-M-50MG/500MG should be used with caution in patients with kidney disease. Metformin is primarily excreted by the kidneys, and impaired renal function can lead to its accumulation and increase the risk of lactic acidosis. Regular monitoring of kidney function is essential.
Liver
CONSULT YOUR DOCTORPatients with severe liver impairment should consult their doctor before taking VILDAGET-M-50MG/500MG. While Vildagliptin is metabolized in the liver, Metformin is contraindicated in severe hepatic dysfunction due to an increased risk of lactic acidosis. Liver function tests should be monitored.
Fact Box
Frequently asked questions by patients
Q: How quickly does VILDAGET-M-50MG/500MG start working?
A: VILDAGET-M starts working to lower blood sugar levels within a few hours of the first dose. However, the full therapeutic effect and significant improvements in HbA1c levels are typically observed after several weeks of consistent use, as part of a comprehensive diabetes management plan.
Q: Can I stop taking VILDAGET-M-50MG/500MG if my blood sugar is normal?
A: No, you should not stop taking VILDAGET-M-50MG/500MG without consulting your doctor, even if your blood sugar levels appear normal. Diabetes is a chronic condition, and stopping medication can lead to a rapid increase in blood sugar, potentially causing serious health complications. Your doctor will advise on any dosage adjustments or discontinuation.
Q: What should I do if I experience severe stomach upset?
A: If you experience severe stomach upset, such as persistent nausea, vomiting, or diarrhea, while taking VILDAGET-M-50MG/500MG, contact your doctor immediately. These symptoms can sometimes indicate a more serious condition like lactic acidosis, especially if accompanied by muscle pain or rapid breathing. Your doctor will evaluate your condition.
Q: Is VILDAGET-M-50MG/500MG suitable for all types of diabetes?
A: No, VILDAGET-M-50MG/500MG is specifically indicated for the treatment of Type 2 Diabetes Mellitus in adults. It is not suitable for Type 1 Diabetes, diabetic ketoacidosis, or for patients with severe kidney impairment. Always ensure your diagnosis is confirmed by a healthcare professional before starting this medication.
Frequently Asked Questions
Q: What is VILDAGET-M-50MG/500MG used for?
VILDAGET-M-50MG/500MG is an oral antidiabetic medication used to improve blood sugar control in adults with Type 2 Diabetes Mellitus. It is typically prescribed when diet and exercise alone, or Metformin monotherapy, are insufficient to manage blood glucose levels effectively. This combination helps to lower both fasting and post-meal blood sugar.
Q: How should I take VILDAGET-M-50MG/500MG?
Take VILDAGET-M-50MG/500MG exactly as prescribed by your doctor. It is usually taken once or twice daily, preferably with meals to minimize gastrointestinal side effects. Swallow the tablet whole with a glass of water; do not crush or chew it. Consistency in taking the medication at the same time each day is important for optimal results.
Q: What are the common side effects of VILDAGET-M-50MG/500MG?
Common side effects may include gastrointestinal disturbances such as nausea, diarrhea, abdominal pain, and indigestion. Other possible side effects are headache and dizziness. These are usually mild and tend to resolve as your body adjusts to the medication. If they persist or worsen, consult your doctor.
Q: Can VILDAGET-M-50MG/500MG cause weight loss?
Metformin, one of the components in VILDAGET-M-50MG/500MG, is often associated with modest weight loss or weight neutrality in patients with Type 2 Diabetes. Vildagliptin is generally weight-neutral. Therefore, this combination medication is less likely to cause weight gain compared to some other antidiabetic drugs, and may even contribute to slight weight reduction in some individuals.
Q: What lifestyle changes should I make while taking VILDAGET-M-50MG/500MG?
To maximize the benefits of VILDAGET-M-50MG/500MG, it is crucial to maintain a healthy lifestyle. This includes following a balanced diet low in sugar and refined carbohydrates, engaging in regular physical activity, and maintaining a healthy weight. Regular monitoring of blood sugar levels and adherence to your doctor's advice are also essential for effective diabetes management.
Additional Information
VILDAGET-M-50MG/500MG offers a robust and effective treatment option for adults managing Type 2 Diabetes Mellitus. By combining the distinct yet complementary mechanisms of Vildagliptin and Metformin, this medication provides comprehensive blood sugar control, helping patients achieve their glycemic targets and reduce the risk of long-term diabetes complications. Its dual action addresses both insulin secretion and insulin sensitivity, making it a valuable addition to a personalized diabetes management plan. It is imperative that VILDAGET-M-50MG/500MG is used under the guidance of a healthcare professional, alongside a healthy diet and regular exercise. Regular monitoring of blood glucose levels, kidney function, and adherence to prescribed dosages are crucial for safe and effective treatment. Patients should be aware of potential side effects and precautions, ensuring open communication with their doctor for any concerns. This medication empowers individuals to take an active role in managing their diabetes and improving their overall health.