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Antidiabetics
LINTAGLIP-5 TAB A/A
SALT COMPOSITION
LINAGLIPTIN 5MGTYPE
TABLET
STORAGE
Store LINTAGLIP-5 TAB A/A below 30°C in a dry place, protected from light and moisture. Keep it out of the reach and sight of children. Do not use after the expiry date.
PRODUCT INTRODUCTION
LINTAGLIP-5 TAB A/A, containing Linagliptin 5mg, is a crucial medication for managing Type 2 Diabetes Mellitus in adults. It helps to effectively lower high blood sugar levels, preventing serious complications associated with uncontrolled diabetes like kidney damage, nerve problems, blindness, and limb loss. As an oral antidiabetic, LINTAGLIP-5 works by enhancing the body's natural ability to reduce blood glucose, making it an important part of a comprehensive diabetes management plan alongside diet and exercise. This medication is designed to provide sustained glycemic control and improve overall patient well-being.
Uses of LINTAGLIP-5 TAB A/A
LINTAGLIP-5 TAB A/A is primarily used for the effective management of Type 2 Diabetes Mellitus.
- Type 2 Diabetes Mellitus
LINTAGLIP-5 is prescribed to adults with Type 2 Diabetes Mellitus to improve glycemic control. It is used either as monotherapy when diet and exercise alone are insufficient, or in combination with other antidiabetic agents like metformin, sulfonylureas, or insulin, when these agents do not provide adequate blood sugar control. It helps in maintaining stable blood glucose levels throughout the day.
Side Effects of LINTAGLIP-5 TAB A/A
Like all medicines, LINTAGLIP-5 can cause side effects, although not everybody gets them. Most side effects are mild and temporary.
Common side effects
- Nasopharyngitis (common cold symptoms)
- Cough
- Diarrhea
- Headache
- Hypoglycemia (when used with sulfonylureas or insulin)
Seek immediate medical attention if you experience any of the following rare but serious side effects:
- Pancreatitis (severe stomach pain, vomiting)
- Severe allergic reactions (rash, swelling of face/throat)
- Bullous pemphigoid (blisters on skin)
- Joint pain (arthralgia)
If any side effect bothers you or persists, please consult your doctor. Do not stop taking the medication without medical advice.
How to use LINTAGLIP-5 TAB A/A
- Adults:
The recommended dose of LINTAGLIP-5 is one 5mg tablet once daily, taken orally with or without food. It should be swallowed whole with water. Adherence to the prescribed dosage and schedule is crucial for optimal therapeutic outcomes. Do not crush or chew the tablet.
- Children:
LINTAGLIP-5 is not recommended for use in children and adolescents below 18 years of age due to insufficient data on safety and efficacy in this population. Consult a pediatrician for appropriate management of diabetes in children.
- Elderly:
No dose adjustment is required for elderly patients based on age alone. However, caution should be exercised, and renal function should be monitored, especially if co-morbidities are present. The physician will determine the most suitable dosage.
- Missed Dose:
If you miss a dose of LINTAGLIP-5, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.
How LINTAGLIP-5 TAB A/A works
Linagliptin, the active ingredient in LINTAGLIP-5, belongs to a class of drugs called Dipeptidyl Peptidase-4 (DPP-4) inhibitors. It works by selectively inhibiting the enzyme DPP-4, which is responsible for inactivating incretin hormones like Glucagon-Like Peptide-1 (GLP-1) and Glucose-Dependent Insulinotropic Polypeptide (GIP). By inhibiting DPP-4, Linagliptin increases the levels of active incretin hormones in the body. These elevated incretin levels lead to a glucose-dependent increase in insulin release from pancreatic beta cells and a decrease in glucagon secretion from pancreatic alpha cells. This dual action helps to reduce blood glucose levels, particularly after meals. Unlike some other antidiabetic medications, Linagliptin has a low risk of hypoglycemia when used as monotherapy, as its effects are glucose-dependent.
Precautions
- Inform your doctor about all your medical conditions, especially kidney or liver problems.
- Discuss any history of pancreatitis or gallstones with your doctor.
- Monitor blood sugar regularly as advised by your physician.
- Be aware of symptoms of hypoglycemia, especially if taking with sulfonylureas or insulin.
- Inform your doctor if you experience severe and persistent joint pain.
- Report any signs of allergic reactions or skin blistering immediately.
Safety Advice
Alcohol
CAUTIONAlcohol consumption can affect blood sugar levels, potentially leading to hypoglycemia or hyperglycemia. It is advisable to limit or avoid alcohol while taking LINTAGLIP-5 and consult your doctor regarding safe consumption.
Pregnancy
CONSULT YOUR DOCTORThere is limited data on the use of Linagliptin in pregnant women. It should only be used if the potential benefit justifies the potential risk to the fetus. Always consult your doctor before taking this medication during pregnancy.
Breastfeeding
CONSULT YOUR DOCTORIt is unknown whether Linagliptin is excreted in human milk. A decision must be made whether to discontinue breastfeeding or to discontinue the drug, taking into account the importance of the drug to the mother. Consult your doctor.
Driving
SAFELINTAGLIP-5 generally does not impair your ability to drive or operate machinery. However, if you experience symptoms of hypoglycemia (dizziness, weakness) when used in combination with other drugs, avoid driving.
Kidney
SAFE IF PRESCRIBEDNo dose adjustment is required for patients with renal impairment, including those with end-stage renal disease. This is a significant advantage of Linagliptin. However, always follow your doctor's specific instructions.
Liver
CONSULT YOUR DOCTORNo dose adjustment is required for patients with mild to moderate hepatic impairment. However, caution is advised in patients with severe hepatic impairment. Consult your doctor for personalized advice.
Fact Box
Frequently asked questions by patients
Q: Can LINTAGLIP-5 be taken with other diabetes medications?
A: Yes, LINTAGLIP-5 can be used as monotherapy or in combination with other antidiabetic agents like metformin, sulfonylureas, or insulin, as advised by your doctor. Always follow your physician's guidance for combination therapy.
Q: What should I do if I experience severe joint pain while taking LINTAGLIP-5?
A: While rare, severe and persistent joint pain has been reported with DPP-4 inhibitors. If you experience such symptoms, contact your doctor immediately for evaluation and advice.
Q: Is LINTAGLIP-5 suitable for patients with kidney problems?
A: A key advantage of Linagliptin (LINTAGLIP-5) is that no dose adjustment is required for patients with any degree of renal impairment, including those on dialysis. However, always consult your doctor.
Q: How quickly does LINTAGLIP-5 start working?
A: LINTAGLIP-5 starts working to lower blood sugar levels shortly after administration. However, the full therapeutic effect and sustained glycemic control are typically observed over several weeks of consistent use, alongside diet and exercise.
Frequently Asked Questions
Q: What is LINTAGLIP-5 used for?
LINTAGLIP-5 (Linagliptin 5mg) is an oral medication used to treat Type 2 Diabetes Mellitus in adults. It helps to lower high blood sugar levels by increasing the body's natural ability to produce insulin and reduce glucagon, thereby improving glycemic control and preventing diabetes-related complications.
Q: How should I take LINTAGLIP-5?
You should take one LINTAGLIP-5 tablet (5mg) once daily, with or without food, as prescribed by your doctor. Swallow the tablet whole with water. It is important to take it at the same time each day to maintain consistent blood levels and ensure optimal effectiveness.
Q: What are the common side effects of LINTAGLIP-5?
Common side effects may include nasopharyngitis (cold symptoms), cough, diarrhea, and headache. When used in combination with sulfonylureas or insulin, there might be an increased risk of hypoglycemia. If any side effects persist or worsen, consult your healthcare provider.
Q: Can LINTAGLIP-5 cause weight gain?
Unlike some other antidiabetic medications, Linagliptin (LINTAGLIP-5) is generally considered weight-neutral or may lead to slight weight loss. It is not typically associated with significant weight gain, making it a favorable option for many patients with Type 2 Diabetes.
Q: What lifestyle changes should I make while taking LINTAGLIP-5?
To maximize the benefits of LINTAGLIP-5, it is crucial to adopt a healthy lifestyle. This includes following a balanced diet low in sugar and saturated fats, engaging in regular physical activity, maintaining a healthy weight, and avoiding smoking. These measures complement the medication in managing Type 2 Diabetes effectively.
Additional Information
LINTAGLIP-5 TAB A/A, containing Linagliptin 5mg, offers an effective and well-tolerated option for adults managing Type 2 Diabetes Mellitus. By specifically targeting the DPP-4 enzyme, it helps to improve the body's natural glucose-regulating mechanisms, leading to better blood sugar control and a reduced risk of long-term diabetic complications. Its unique renal excretion profile means no dose adjustment is needed for kidney patients, adding to its versatility. Always remember that LINTAGLIP-5 should be used as part of a comprehensive diabetes management plan that includes a healthy diet, regular exercise, and consistent monitoring of blood glucose levels. Regular consultations with your healthcare provider are essential to ensure the medication is working effectively and to address any concerns or side effects. Adherence to the prescribed regimen is key to achieving optimal health outcomes and living a healthier life with diabetes.