GLYGIMET-SR 1GM TAB

Uses of GLYGIMET-SR 1GM TAB

GLYGIMET-SR 1GM TAB is primarily indicated for the following conditions:

• Type 2 Diabetes Mellitus

  GLYGIMET-SR 1GM TAB is used to improve blood sugar control in adults with Type 2 Diabetes Mellitus. It is often prescribed as a first-line therapy, especially in overweight or obese patients, when diet and exercise alone are not enough to manage blood glucose levels. It helps to reduce the risk of diabetes-related complications by maintaining stable glucose readings.

• Polycystic Ovary Syndrome (PCOS)

  While not its primary indication, Metformin is sometimes used off-label in women with Polycystic Ovary Syndrome (PCOS). It can help improve insulin resistance, regulate menstrual cycles, and reduce androgen levels, thereby assisting with fertility issues and other symptoms associated with PCOS. This use should always be under strict medical supervision.

• Prevention of Type 2 Diabetes

  In some cases, GLYGIMET-SR 1GM TAB may be prescribed to individuals at high risk of developing Type 2 Diabetes, such as those with prediabetes, especially if they are overweight and have a history of gestational diabetes or a family history of diabetes. It helps to delay or prevent the onset of the disease when combined with lifestyle modifications.

Side Effects of GLYGIMET-SR 1GM TAB

Like all medicines, GLYGIMET-SR 1GM TAB can cause side effects, although not everybody gets them. Most side effects are mild and temporary, but some can be serious.

Serious but rare side effects include:

If any of these side effects bother you or do not go away, please consult your doctor. Seek immediate medical attention if you experience symptoms of lactic acidosis such as severe tiredness, unusual muscle pain, trouble breathing, stomach pain, dizziness, or a very slow or irregular heartbeat.

How to use GLYGIMET-SR 1GM TAB

• Adults:

  The usual starting dose for GLYGIMET-SR 1GM TAB is 500 mg once daily with the evening meal. The dose may be gradually increased by 500 mg weekly, up to a maximum of 2000 mg (2 tablets of 1GM) once daily, taken with the evening meal. It is crucial to follow your doctor's instructions regarding dosage and administration. Swallow the tablet whole; do not crush, chew, or break it.

• Children:

  GLYGIMET-SR 1GM TAB is generally not recommended for use in children under 10 years of age. For adolescents (10-17 years) with Type 2 Diabetes, the dosage should be determined by a specialist, starting with a lower dose and gradually titrating upwards under strict medical supervision. Always consult a pediatrician for appropriate dosing.

• Elderly:

  Elderly patients should be monitored closely for renal function due to the increased risk of lactic acidosis. A lower starting dose may be considered, and the dosage should be adjusted based on renal function assessment. Regular kidney function tests are recommended. Always consult a doctor for personalized advice.

• Missed Dose:

  If you miss a dose of GLYGIMET-SR 1GM TAB, take it as soon as you remember, unless it is almost time for your next dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one, as this can increase the risk of side effects.

How GLYGIMET-SR 1GM TAB works

Metformin, the active ingredient in GLYGIMET-SR 1GM TAB, works through multiple mechanisms to lower blood glucose levels. Its primary action involves reducing glucose production by the liver (hepatic gluconeogenesis). It achieves this by inhibiting enzymes involved in glucose synthesis, leading to a significant decrease in the amount of glucose released into the bloodstream, particularly during fasting states. Additionally, Metformin improves insulin sensitivity in peripheral tissues, such as muscle and fat cells. This allows these cells to absorb and utilize glucose more effectively from the blood, even when insulin levels are not optimal. It also slightly decreases glucose absorption from the gastrointestinal tract. The sustained-release (SR) formulation ensures a gradual and consistent release of Metformin, maintaining therapeutic concentrations over an extended period. This steady action helps in better glycemic control throughout the day and night, contributing to improved patient compliance and reduced incidence of gastrointestinal discomfort often associated with immediate-release Metformin.

Precautions

• Inform your doctor if you have kidney or liver problems before starting this medication.
• Avoid excessive alcohol consumption while taking GLYGIMET-SR 1GM TAB, as it increases the risk of lactic acidosis.
• Inform your doctor if you are scheduled for any surgery or diagnostic procedures involving iodinated contrast agents, as Metformin may need to be temporarily stopped.
• Maintain a healthy diet and regular exercise regimen as advised by your doctor.
• Regularly monitor your blood glucose levels and kidney function as recommended by your healthcare provider.
• Do not stop taking GLYGIMET-SR 1GM TAB without consulting your doctor, even if you feel well.

Safety Advice

Alcohol

UNSAFE

Consumption of alcohol while taking GLYGIMET-SR 1GM TAB is unsafe. Alcohol can increase the risk of a rare but serious side effect called lactic acidosis, which can be life-threatening. It is best to avoid alcohol entirely or consume it in very limited quantities only after consulting your doctor.

Pregnancy

CONSULT YOUR DOCTOR

GLYGIMET-SR 1GM TAB is generally not recommended during pregnancy unless clearly necessary and prescribed by a doctor. Uncontrolled diabetes during pregnancy can lead to complications for both mother and baby. Your doctor will weigh the benefits against the risks and may suggest alternative treatments or insulin therapy.

Breastfeeding

CONSULT YOUR DOCTOR

Small amounts of Metformin may pass into breast milk. While generally considered safe for the infant at therapeutic doses, it is crucial to consult your doctor before breastfeeding while taking GLYGIMET-SR 1GM TAB. Your doctor will assess the potential risks and benefits for your baby.

Driving

SAFE

GLYGIMET-SR 1GM TAB usually does not cause hypoglycemia (low blood sugar) when taken alone, so it is generally safe to drive. However, if taken with other antidiabetic medications or if you experience symptoms like dizziness or blurred vision, avoid driving and operating machinery.

Kidney

CAUTION

GLYGIMET-SR 1GM TAB should be used with caution in patients with kidney impairment. It is contraindicated in severe kidney disease due to the increased risk of lactic acidosis. Your doctor will assess your kidney function before and during treatment and adjust the dosage accordingly.

Liver

CAUTION

Patients with liver disease should use GLYGIMET-SR 1GM TAB with caution. Impaired liver function can increase the risk of lactic acidosis, a serious complication. Regular monitoring of liver function tests may be required. Always consult your doctor for personalized advice regarding liver health.

Fact Box

Frequently asked questions by patients

Frequently Asked Questions

Additional Information