Neurological

PREGABLEN-M CAP

Prescription Required

SALT COMPOSITION

PREGABALIN-75+METHYLCOBALAMIN 750MCG CAP

TYPE

CAPSULE

STORAGE

Store below 30°C in a cool, dry place, protected from light and moisture. Keep out of reach of children.

PRODUCT INTRODUCTION

PREGABLEN-M CAP is a combination medication specifically formulated to address neuropathic pain and support nerve health. It contains Pregabalin, an anticonvulsant and analgesic, and Methylcobalamin, an active form of Vitamin B12 essential for nerve regeneration. This powerful combination works synergistically to alleviate chronic nerve pain, reduce tingling and numbness, and promote the repair of damaged nerve cells. Often prescribed for conditions like diabetic neuropathy, post-herpetic neuralgia, and fibromyalgia, PREGABLEN-M CAP helps improve the quality of life for patients suffering from persistent nerve discomfort. It is an effective solution for managing symptoms associated with various neurological disorders.

Uses of PREGABLEN-M CAP

PREGABLEN-M CAP is primarily used to treat various forms of neuropathic pain and to support nerve health.

Diabetic Neuropathy
This medication effectively reduces nerve pain, burning, tingling, and numbness associated with nerve damage caused by diabetes. It helps improve nerve function and alleviate discomfort in affected areas.
Post-Herpetic Neuralgia
PREGABLEN-M CAP is prescribed to manage the persistent, severe nerve pain that can occur after a shingles (herpes zoster) infection has cleared. It helps to calm the overactive nerve signals responsible for this chronic pain.
Fibromyalgia
It is used to relieve widespread musculoskeletal pain, fatigue, and tenderness in specific areas of the body characteristic of fibromyalgia. The combination helps in managing both pain and associated neurological symptoms.

Side Effects of PREGABLEN-M CAP

Like all medicines, PREGABLEN-M CAP can cause side effects, although not everybody gets them. Most side effects are mild to moderate and temporary.

Common side effects

Dizziness
Drowsiness
Blurred vision
Weight gain
Swelling of hands or feet

Seek immediate medical attention if you experience any of the following rare but serious side effects:

Allergic reactions (rash, swelling, difficulty breathing)
Mood changes or suicidal thoughts
Muscle pain or weakness
Severe skin reactions

If any side effect bothers you or persists, please consult your doctor. Do not stop taking the medication without consulting your healthcare provider.

How to use PREGABLEN-M CAP

Adults:
Typically, one capsule once or twice daily, as directed by a physician. The dosage may be adjusted based on the patient's response and tolerability. It should be taken with or without food.
Children:
The safety and efficacy of PREGABLEN-M CAP in children and adolescents below 18 years of age have not been established. Use in this age group is generally not recommended unless specifically advised by a specialist.
Elderly:
Elderly patients may require a lower starting dose due to potential age-related decline in renal function. Close monitoring for side effects like dizziness and drowsiness is recommended.
Missed Dose:
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.

How PREGABLEN-M CAP works

Pregabalin, a key component of PREGABLEN-M CAP, exerts its action by binding to the alpha-2-delta subunit of voltage-gated calcium channels in the central nervous system. This binding modulates the influx of calcium into nerve terminals, thereby reducing the release of several excitatory neurotransmitters such as glutamate, noradrenaline, and substance P. This reduction in neurotransmitter release helps to calm overactive nerve signals, which are often responsible for neuropathic pain, leading to significant pain relief. Methylcobalamin, the active form of Vitamin B12, plays a crucial role in nerve health and regeneration. It is essential for the synthesis of myelin, the protective sheath around nerve fibers, and for the proper functioning of the nervous system. Methylcobalamin aids in the repair of damaged nerve cells, promotes nerve regeneration, and helps in the production of red blood cells, which carry oxygen to nerves. Its neuroprotective properties complement Pregabalin's pain-relieving effects, offering a comprehensive approach to managing neuropathic conditions and improving overall nerve function.

Precautions

Inform your doctor if you have kidney disease, as dose adjustment may be necessary.
Be cautious if you have a history of heart problems or diabetes.
Avoid sudden discontinuation of the medication, as it may lead to withdrawal symptoms.
Report any changes in mood, behavior, or suicidal thoughts to your doctor immediately.
Use with caution in patients with a history of drug abuse or dependence.
May cause dizziness and drowsiness, so avoid driving or operating heavy machinery until you know how it affects you.

Safety Advice

Alcohol

UNSAFE

Consumption of alcohol with PREGABLEN-M CAP can increase the risk of dizziness, drowsiness, and impaired judgment. It is strongly advised to avoid alcohol during treatment.

Pregnancy

CONSULT YOUR DOCTOR

PREGABLEN-M CAP is generally not recommended during pregnancy unless clearly necessary. Consult your doctor to weigh the potential risks and benefits before use.

Breastfeeding

CONSULT YOUR DOCTOR

Pregabalin is known to pass into breast milk. It is advisable to consult your doctor before breastfeeding while taking this medication.

Driving

UNSAFE

PREGABLEN-M CAP can cause dizziness, drowsiness, and blurred vision. Avoid driving or operating heavy machinery until you are certain you can perform such activities safely.

Kidney

CAUTION

Patients with kidney disease may require a dose adjustment of PREGABLEN-M CAP. Consult your doctor for appropriate dosing based on your kidney function.

Liver

CAUTION

While Pregabalin is primarily excreted unchanged, Methylcobalamin is processed by the liver. Use with caution in patients with severe liver impairment and consult your doctor.

Fact Box

Chemical Class

Gamma-aminobutyric acid analogue (Pregabalin), Vitamin B12 (Methylcobalamin)

Habit Forming

Yes

Therapeutic Class

Anticonvulsant, Neuropathic Pain Agent, Vitamin B12 Supplement

Action Class

Pain modulator, Nerve regenerator

Frequently asked questions by patients

Q: Can PREGABLEN-M CAP be taken for general body pain?

A: PREGABLEN-M CAP is specifically formulated for neuropathic pain, which is pain caused by nerve damage. It is not typically used for general body aches or muscular pain. Consult your doctor for appropriate treatment for general pain.

Q: How long does it take for PREGABLEN-M CAP to show results?

A: The onset of action can vary among individuals. While some patients may experience relief within a few days, it often takes several weeks of consistent use to achieve the full therapeutic benefits, especially for nerve regeneration. Follow your doctor's prescribed duration.

Q: Is PREGABLEN-M CAP safe for long-term use?

A: PREGABLEN-M CAP can be prescribed for long-term management of chronic neuropathic pain under strict medical supervision. Regular follow-ups with your doctor are essential to monitor for side effects and assess the ongoing need for the medication.

Q: What should I do if I experience withdrawal symptoms after stopping PREGABLEN-M CAP?

A: Do not stop PREGABLEN-M CAP suddenly without consulting your doctor, as it can lead to withdrawal symptoms like anxiety, insomnia, nausea, or sweating. Your doctor will guide you on a gradual dose reduction schedule to minimize these effects.

Frequently Asked Questions

Q: What is PREGABLEN-M CAP used for?

PREGABLEN-M CAP is primarily used to treat neuropathic pain conditions such as diabetic neuropathy, post-herpetic neuralgia, and fibromyalgia. It combines Pregabalin for pain relief and Methylcobalamin for nerve health and regeneration, helping to reduce symptoms like burning, tingling, and numbness.

Q: Can PREGABLEN-M CAP cause weight gain?

Yes, weight gain is a known common side effect of Pregabalin, one of the active ingredients in PREGABLEN-M CAP. This can be due to increased appetite or fluid retention. If you are concerned about weight gain, discuss it with your doctor, who may suggest dietary adjustments or alternative treatments.

Q: Is PREGABLEN-M CAP habit-forming?

Yes, Pregabalin, a component of PREGABLEN-M CAP, has the potential for abuse and dependence, especially at higher doses or in individuals with a history of substance abuse. It is crucial to take this medication exactly as prescribed by your doctor and not to exceed the recommended dosage.

Q: Can I take PREGABLEN-M CAP with other pain relievers?

Combining PREGABLEN-M CAP with other pain relievers, especially those that cause drowsiness or affect the central nervous system, should only be done under medical supervision. Always inform your doctor about all medications you are taking to avoid potential drug interactions or enhanced side effects.

Q: What are the dietary considerations while taking PREGABLEN-M CAP?

There are no specific dietary restrictions directly related to PREGABLEN-M CAP, but maintaining a balanced diet is always beneficial for overall health. However, it is important to avoid alcohol consumption as it can intensify side effects like dizziness and drowsiness. Discuss any dietary concerns with your healthcare provider.