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Neurological
PREGABLEN-75 CAP
SALT COMPOSITION
PREGABALIN-75 MG CAPTYPE
CAPSULE
STORAGE
Store PREGABLEN-75 CAP below 30°C in a cool, dry place, protected from direct light and moisture. Keep this and all medications out of the sight and reach of children.
PRODUCT INTRODUCTION
PREGABLEN-75 CAP is a widely prescribed medication containing Pregabalin 75 mg, primarily utilized for the effective management of neuropathic pain, epilepsy, and generalized anxiety disorder. This medication offers significant relief from chronic nerve pain caused by conditions such as diabetes, shingles, or spinal cord injury. It also serves as an important adjunctive therapy for adults experiencing partial-onset seizures and helps alleviate the debilitating symptoms of generalized anxiety. By calming overactive nerve signals, PREGABLEN-75 CAP aims to improve patients' overall quality of life and daily functioning.
Uses of PREGABLEN-75 CAP
PREGABLEN-75 CAP is a versatile medication prescribed for several conditions where nerve pain, seizures, or anxiety are prominent clinical challenges.
- Neuropathic Pain
PREGABLEN-75 CAP is highly effective in treating various forms of neuropathic pain, which results from nerve damage. This includes diabetic neuropathy, post-herpetic neuralgia (pain after shingles), and pain associated with spinal cord injury. It works by calming the damaged nerves, significantly reducing burning, shooting, tingling, and numbness sensations, thereby improving patient comfort and mobility.
- Epilepsy
As an adjunctive therapy, PREGABLEN-75 CAP is used to help control partial-onset seizures in adults. When added to other antiepileptic drugs, it reduces the frequency and severity of seizures by stabilizing abnormal electrical activity in the brain. This provides better seizure control and enhances the overall management plan for patients with epilepsy.
- Generalized Anxiety Disorder (GAD)
This medication is also indicated for the management of generalized anxiety disorder in adults. It helps alleviate persistent and excessive worry, restlessness, irritability, muscle tension, and sleep disturbances associated with GAD. By modulating brain chemicals, PREGABLEN-75 CAP contributes to a calming effect, leading to a noticeable improvement in anxiety symptoms and overall well-being.
Side Effects of PREGABLEN-75 CAP
Like all medicines, PREGABLEN-75 CAP can cause side effects, although not everyone experiences them. Most side effects are mild to moderate and tend to be temporary as your body adjusts to the medication.
Common side effects
- Dizziness
- Drowsiness
- Blurred vision
- Weight gain
- Swelling of hands/feet (peripheral edema)
Seek immediate medical attention if you experience any of these rare but potentially serious side effects:
- Allergic reactions (rash, hives, swelling of face/lips/tongue/throat)
- Thoughts of self-harm or suicide
- Muscle pain, tenderness, or weakness (especially if accompanied by fever)
If any side effect bothers you, persists, or worsens, please consult your doctor promptly. Do not discontinue the medication without consulting your healthcare provider, as this may lead to withdrawal symptoms.
How to use PREGABLEN-75 CAP
- Adults:
The typical starting dose for adults is 75 mg twice daily. Your doctor may gradually increase the dose based on your response and tolerability, usually up to a maximum of 300 mg twice daily. Always follow your doctor's specific instructions regarding dosage and duration of treatment. Take the capsule with or without food.
- Children:
The safety and efficacy of PREGABLEN-75 CAP in children and adolescents below 17 years of age have not been definitively established. Therefore, it is generally not recommended for pediatric use unless specifically advised and monitored by a specialist physician.
- Elderly:
Elderly patients (over 65 years) may require a lower starting dose and slower dose titration due to potential age-related decline in kidney function. Close monitoring for side effects is crucial in this population. Your doctor will adjust the dose based on your kidney function.
- Missed Dose:
If you miss a dose of PREGABLEN-75 CAP, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to compensate for a missed one.
How PREGABLEN-75 CAP works
Pregabalin, the active ingredient in PREGABLEN-75 CAP, exerts its therapeutic effects by binding to the alpha-2-delta subunit of voltage-gated calcium channels located in the central nervous system. This specific binding modulates the influx of calcium ions, which in turn reduces the release of several excitatory neurotransmitters, including glutamate, noradrenaline, and substance P. These neurotransmitters are crucial mediators in the pathways of pain transmission, seizure generation, and anxiety. By diminishing the excessive release of these neurochemicals, Pregabalin helps to stabilize neuronal hyperexcitability. In neuropathic pain, it dampens the abnormal firing of damaged nerves. For epilepsy, it contributes to preventing the spread of seizure activity within the brain. In generalized anxiety disorder, this modulatory action leads to a calming effect, thereby reducing the physiological and psychological manifestations of anxiety.
Precautions
- Do not stop taking PREGABLEN-75 CAP suddenly without consulting your doctor, as it may lead to withdrawal symptoms.
- Inform your doctor if you have kidney problems, as dose adjustment may be necessary based on your renal function.
- Exercise caution while driving or operating heavy machinery, as this medicine can cause dizziness, drowsiness, and blurred vision.
- Report any mood changes, depression, or suicidal thoughts to your doctor immediately, especially during early treatment.
- Inform your doctor about all other medications you are taking, including over-the-counter drugs, herbal supplements, and vitamins.
- Avoid alcohol consumption while on this medication as it can significantly increase drowsiness and dizziness, impairing your coordination.
Safety Advice
Alcohol
UNSAFEAlcohol can significantly enhance the sedative effects of PREGABLEN-75 CAP, leading to severe dizziness, drowsiness, and impaired coordination. It is strongly advised to avoid alcohol consumption during your treatment with this medication.
Pregnancy
CONSULT YOUR DOCTORPREGABLEN-75 CAP is generally not recommended during pregnancy unless the potential benefits clearly outweigh the potential risks to the fetus. Always consult your doctor to discuss the risks and benefits before taking this medicine if you are pregnant or planning a pregnancy.
Breastfeeding
CONSULT YOUR DOCTORPregabalin is known to pass into breast milk. Therefore, it is advisable to consult your doctor before breastfeeding while on PREGABLEN-75 CAP. Your doctor will help you weigh the potential risks to the infant against the benefits of continuing treatment.
Driving
UNSAFEPREGABLEN-75 CAP can cause dizziness, drowsiness, and blurred vision, which can significantly impair your ability to drive or operate heavy machinery safely. It is strongly advised to avoid such activities until you are certain how the medication affects you.
Kidney
CAUTIONDose adjustment of PREGABLEN-75 CAP is often required for patients with kidney impairment. Your doctor will determine the appropriate dosage based on your kidney function tests to prevent accumulation and potential side effects.
Liver
SAFE IF PRESCRIBEDPregabalin is primarily excreted unchanged by the kidneys, with minimal metabolism by the liver. Therefore, severe liver disease is generally not a major concern. However, always consult your doctor if you have any pre-existing liver conditions.
Fact Box
Frequently asked questions by patients
Q: Can PREGABLEN-75 CAP be stopped suddenly?
A: No, PREGABLEN-75 CAP should not be stopped suddenly without consulting your doctor. Abrupt discontinuation can lead to withdrawal symptoms such as insomnia, headache, nausea, anxiety, and sweating. Your doctor will advise a gradual dose reduction schedule to safely discontinue the medication.
Q: Does PREGABLEN-75 CAP cause weight gain?
A: Yes, weight gain is a common side effect associated with PREGABLEN-75 CAP. This is often attributed to increased appetite and fluid retention. Monitoring your diet, maintaining a healthy lifestyle, and engaging in regular physical activity can help manage this potential side effect.
Q: Is PREGABLEN-75 CAP addictive?
A: PREGABLEN-75 CAP has a potential for abuse and dependence, especially at higher doses or in individuals with a history of substance abuse. It is crucial to take this medication strictly as prescribed by your doctor and to report any concerns about dependence or misuse.
Q: How long does it take for PREGABLEN-75 CAP to work?
A: The onset of action for PREGABLEN-75 CAP can vary depending on the condition being treated. For neuropathic pain, some relief may be felt within a week, but full therapeutic effects might take several weeks. For anxiety, improvement can often be noticed relatively quickly, sometimes within a few days to a week.
Frequently Asked Questions
Q: What is PREGABLEN-75 CAP primarily used for?
PREGABLEN-75 CAP is primarily used to treat neuropathic pain, which is nerve pain caused by conditions like diabetes, shingles, or spinal cord injury. It also serves as an add-on therapy for partial-onset seizures in adults and is effective in managing generalized anxiety disorder, helping to calm overactive nerve signals.
Q: What are the most common side effects of PREGABLEN-75 CAP?
The most common side effects associated with PREGABLEN-75 CAP include dizziness, drowsiness, blurred vision, weight gain, and swelling in the hands or feet (peripheral edema). These effects are usually mild and tend to resolve as your body adjusts to the medication. If they persist or worsen, consult your doctor.
Q: Can I drive or operate machinery while taking PREGABLEN-75 CAP?
No, it is generally not recommended to drive or operate heavy machinery after taking PREGABLEN-75 CAP, especially when you first start the medication or after a dose increase. This medication can cause significant dizziness, drowsiness, and blurred vision, which can impair your ability to perform such tasks safely and increase the risk of accidents.
Q: Is PREGABLEN-75 CAP safe during pregnancy or breastfeeding?
PREGABLEN-75 CAP should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus, and only under strict medical supervision. It passes into breast milk, so it is crucial to consult your doctor before breastfeeding while on this medication to discuss the potential risks and benefits for both mother and infant.
Q: What should I do if I accidentally take more than the prescribed dose?
If you accidentally take more than the prescribed dose of PREGABLEN-75 CAP, seek immediate medical attention. Overdose symptoms may include severe drowsiness, confusion, agitation, and seizures. Contact your doctor or the nearest emergency room without delay, even if you do not feel unwell.
Additional Information
PREGABLEN-75 CAP, containing Pregabalin 75 mg, stands as a crucial therapeutic option for individuals grappling with chronic neuropathic pain, partial-onset seizures, and generalized anxiety disorder. Its targeted action on voltage-gated calcium channels effectively modulates neurotransmitter release, thereby calming overactive nerve signals and providing significant symptomatic relief, ultimately enhancing the patient's quality of life. Adherence to the prescribed dosage and a gradual discontinuation process, under medical guidance, are paramount to ensure treatment efficacy and prevent potential withdrawal symptoms. While generally well-tolerated, awareness of common side effects such as dizziness and drowsiness, alongside strict adherence to safety precautions, is essential for safe and effective management. Patients are always encouraged to maintain open communication with their healthcare provider for personalized advice and to address any concerns regarding their treatment with PREGABLEN-75 CAP.
