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Neurological
GABANEC-300 CAP
SALT COMPOSITION
GABAPENTIN 300MGTYPE
CAPSULE
STORAGE
Store GABANEC-300 CAP below 30°C in a cool, dry place. Protect from light and moisture. Keep out of the reach and sight of children.
PRODUCT INTRODUCTION
GABANEC-300 CAP, containing Gabapentin 300mg, is a widely prescribed medication in India for the management of various neurological conditions. It is primarily used to treat neuropathic pain, a type of pain caused by nerve damage, and as an adjunctive therapy for partial seizures in epilepsy. This medication helps improve the quality of life for patients suffering from chronic pain and seizure disorders by reducing the frequency and intensity of symptoms. Always consult a healthcare professional before starting or stopping GABANEC-300 CAP to ensure it is appropriate for your specific condition and to understand proper dosage and potential side effects.
Uses of GABANEC-300 CAP
GABANEC-300 CAP is prescribed for various conditions, primarily focusing on neurological disorders.
- Neuropathic Pain
It is highly effective in treating neuropathic pain, which arises from nerve damage. This includes conditions like post-herpetic neuralgia (nerve pain after shingles), diabetic neuropathy, and other forms of chronic nerve pain. Gabapentin helps reduce burning, shooting, and stabbing sensations, significantly improving patient comfort and daily functioning.
- Epilepsy (Partial Seizures)
GABANEC-300 CAP is used as an add-on therapy for the treatment of partial seizures with or without secondary generalization in adults and children aged 12 years and above. It helps to stabilize electrical activity in the brain, thereby reducing the frequency and severity of epileptic seizures and improving seizure control when used with other antiepileptic drugs.
- Restless Legs Syndrome (RLS)
Although not its primary indication, Gabapentin is sometimes prescribed off-label for the symptomatic treatment of moderate to severe primary Restless Legs Syndrome. It helps alleviate the uncomfortable sensations and irresistible urge to move the legs, particularly at night, leading to improved sleep quality for affected individuals.
Side Effects of GABANEC-300 CAP
Like all medicines, GABANEC-300 CAP can cause side effects, although not everybody gets them. Most side effects are mild to moderate and often decrease over time as your body adjusts to the medication.
Common side effects
- Dizziness
- Drowsiness
- Fatigue
- Ataxia (impaired coordination)
- Blurred vision
Less common but more serious side effects require immediate medical attention.
- Suicidal thoughts or behavior
- Severe skin reactions (e.g., Stevens-Johnson syndrome)
- Angioedema (swelling of face, lips, tongue)
If any side effect bothers you or persists, please consult your doctor. Do not stop taking the medicine without medical advice.
How to use GABANEC-300 CAP
- Adults:
For neuropathic pain, the usual starting dose is 300mg once daily on day 1, 300mg twice daily on day 2, and 300mg three times daily on day 3. The dose can then be gradually increased up to a maximum of 1800-3600mg per day in divided doses, based on individual response and tolerability. For epilepsy, the initial dose is typically 300mg three times daily, which can be titrated up to 900-3600mg per day in three divided doses.
- Children:
GABANEC-300 CAP is generally not recommended for children under 12 years for epilepsy, and its use for neuropathic pain in children should be under strict medical supervision. Dosing for children aged 12 years and above for epilepsy is similar to adults, starting with 300mg three times daily and titrating as needed under a doctor's guidance.
- Elderly:
Elderly patients may require a lower starting dose and slower titration due to potential age-related decrease in renal function. Dosage adjustments should be made based on creatinine clearance. Close monitoring for side effects like dizziness and drowsiness is crucial in this population.
- Missed Dose:
If you miss a dose of GABANEC-300 CAP, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one, as this can increase the risk of side effects. Consult your doctor if you are unsure.
How GABANEC-300 CAP works
Gabapentin, the active ingredient in GABANEC-300 CAP, is an anticonvulsant and neuropathic pain agent. While its exact mechanism of action is not fully understood, it is believed to exert its effects by modulating the release of several neurotransmitters. It selectively binds to the alpha-2-delta subunit of voltage-gated calcium channels in the central nervous system, which is thought to reduce the influx of calcium into nerve terminals. This action decreases the release of excitatory neurotransmitters, thereby stabilizing nerve activity. This modulation of neurotransmitter release contributes to its anticonvulsant properties by reducing neuronal excitability and its analgesic effects by dampening hypersensitive nerve responses responsible for neuropathic pain. Gabapentin does not bind to GABA-A or GABA-B receptors, nor does it inhibit GABA uptake or degradation, distinguishing its mechanism from traditional GABAergic drugs. Its unique action helps to alleviate symptoms without directly affecting GABA levels.
Precautions
- Do not stop taking GABANEC-300 CAP abruptly, as this can lead to withdrawal symptoms or increased seizure frequency.
- Exercise caution while driving or operating machinery, as it may cause dizziness, drowsiness, or blurred vision.
- Inform your doctor if you have kidney problems, as dose adjustments may be necessary.
- Monitor for changes in mood or behavior, including suicidal thoughts, especially at the beginning of treatment or after dose changes.
- Avoid alcohol consumption while on this medication, as it can intensify central nervous system side effects.
- Inform your doctor about all other medications you are taking to avoid potential drug interactions.
Safety Advice
Alcohol
UNSAFEConsumption of alcohol with GABANEC-300 CAP is not recommended. Alcohol can increase the sedative effects of Gabapentin, leading to enhanced dizziness, drowsiness, and impaired coordination. This combination can significantly impair your ability to perform tasks requiring mental alertness.
Pregnancy
CONSULT YOUR DOCTORGABANEC-300 CAP should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Animal studies have shown adverse effects, and human data is limited. Always discuss the risks and benefits with your doctor if you are pregnant or planning to conceive.
Breastfeeding
CONSULT YOUR DOCTORGabapentin is known to be excreted into human breast milk. While the effects on a nursing infant are generally considered low, it is crucial to consult your doctor before breastfeeding. Your doctor will weigh the benefits of treatment for you against the potential risks to your baby.
Driving
UNSAFEGABANEC-300 CAP can cause dizziness, drowsiness, and blurred vision, which may impair your ability to drive or operate heavy machinery safely. It is advisable to avoid such activities until you know how the medication affects you. Always prioritize your safety and the safety of others.
Kidney
CAUTIONGabapentin is primarily excreted unchanged by the kidneys. Patients with impaired kidney function may require dose adjustments to prevent accumulation and increased side effects. Regular monitoring of kidney function and consultation with a doctor are essential for safe use.
Liver
SAFE IF PRESCRIBEDGabapentin is not significantly metabolized by the liver, so dose adjustments are generally not required for patients with liver disease. However, if you have severe liver impairment or co-existing conditions, it is always best to consult your doctor for personalized advice.
Fact Box
Frequently asked questions by patients
Q: How long does it take for GABANEC-300 CAP to start working?
A: The effects of GABANEC-300 CAP may not be immediately noticeable. For neuropathic pain, it might take a few days to a few weeks to experience significant relief as the dose is gradually increased. For epilepsy, seizure control can improve over several weeks of consistent use.
Q: Can I stop taking GABANEC-300 CAP if I feel better?
A: No, you should not stop taking GABANEC-300 CAP suddenly, even if you feel better. Abrupt discontinuation can lead to withdrawal symptoms, such as anxiety, insomnia, nausea, pain, and sweating, or even an increase in seizure frequency. Always consult your doctor for a gradual dose reduction plan.
Q: Does GABANEC-300 CAP cause weight gain?
A: Weight gain is a reported side effect of Gabapentin, though it does not affect everyone. If you are concerned about weight changes, discuss this with your doctor. Maintaining a balanced diet and regular exercise can help manage potential weight fluctuations.
Q: Is GABANEC-300 CAP addictive?
A: Gabapentin is not considered habit-forming in the same way as opioids or benzodiazepines. However, some individuals may experience withdrawal symptoms upon abrupt cessation, indicating a physical dependence. It should always be used as prescribed by a doctor.
Frequently Asked Questions
Q: What should I do if I experience severe dizziness or drowsiness?
If you experience severe dizziness or drowsiness while taking GABANEC-300 CAP, avoid driving or operating heavy machinery. Rest in a safe place and contact your doctor. They may suggest adjusting your dose or recommend alternative strategies to manage these side effects.
Q: Can GABANEC-300 CAP interact with other medications?
Yes, GABANEC-300 CAP can interact with certain medications, including antacids (which can reduce absorption), opioids (increasing CNS depression), and other CNS depressants. Always inform your doctor or pharmacist about all prescription, over-the-counter, and herbal supplements you are taking to prevent potential interactions.
Q: Is GABANEC-300 CAP safe for long-term use?
GABANEC-300 CAP is often prescribed for long-term management of chronic conditions like neuropathic pain and epilepsy. When used under medical supervision, with regular monitoring and appropriate dosing, it is generally considered safe for extended periods. Your doctor will periodically assess your need for continued therapy.
Q: What are the signs of an allergic reaction to GABANEC-300 CAP?
Signs of an allergic reaction may include rash, itching, swelling (especially of the face, tongue, or throat), severe dizziness, or trouble breathing. If you experience any of these symptoms, seek immediate medical attention. These reactions are rare but can be serious.
Q: Can GABANEC-300 CAP be taken with food?
GABANEC-300 CAP can be taken with or without food. Taking it with food may help reduce stomach upset in some individuals. Consistency in how you take it (always with food or always without) is often recommended to maintain stable drug levels.
Additional Information
GABANEC-300 CAP, powered by Gabapentin 300mg, offers significant relief for individuals battling neuropathic pain and partial seizures. Its targeted action helps stabilize nerve activity, leading to improved symptom control and a better quality of life. As a prescription medication, its usage requires careful medical guidance to ensure optimal efficacy and safety. Patients are encouraged to adhere strictly to their prescribed dosage and not to discontinue the medication abruptly. Regular follow-ups with a healthcare provider are essential for monitoring progress, managing potential side effects, and making any necessary dose adjustments. By understanding its benefits, proper administration, and precautions, patients can effectively manage their neurological conditions with GABANEC-300 CAP, contributing to overall well-being and symptom alleviation.
