Neurological

OLENZATAS-5 TAB

Prescription Required

SALT COMPOSITION

OLANZAPINE 5MG

TYPE

TABLET

STORAGE

Store below 25°C, protect from light and moisture. Keep out of reach of children.

PRODUCT INTRODUCTION

OLENZATAS-5 TAB, containing Olanzapine 5mg, is a crucial medication primarily used in the management of schizophrenia and bipolar disorder. As an atypical antipsychotic, it helps restore the balance of certain natural substances in the brain, thereby improving mood, thinking, and behavior. This medication is widely prescribed in India for its efficacy in controlling psychotic symptoms and stabilizing mood swings. It is an essential tool for long-term management, aiming to enhance the quality of life for patients by reducing the severity and frequency of episodes.

Uses of OLENZATAS-5 TAB

OLENZATAS-5 TAB is prescribed for various mental health conditions, offering relief from distressing symptoms.

Schizophrenia
OLENZATAS-5 TAB is highly effective in treating schizophrenia, a chronic mental disorder characterized by distorted thinking, hallucinations, delusions, and severe impairments in daily functioning. It helps manage both positive and negative symptoms, improving thought processes and emotional responses. Regular use helps prevent relapses and maintains mental stability.
Bipolar Mania
This medication is used for the acute treatment of manic or mixed episodes associated with bipolar I disorder. It helps to stabilize mood, reduce hyperactivity, irritability, and racing thoughts often seen during manic phases. It can be used alone or in combination with other mood stabilizers to achieve optimal therapeutic outcomes.
Bipolar Maintenance
OLENZATAS-5 TAB is also indicated for the long-term maintenance treatment of bipolar I disorder. By preventing the recurrence of manic, mixed, or depressive episodes, it helps patients maintain a stable mood and improves their overall quality of life, reducing the frequency and severity of mood swings and promoting sustained well-being.

Side Effects of OLENZATAS-5 TAB

Like all medications, OLENZATAS-5 TAB can cause side effects, although not everybody gets them. Most side effects are mild to moderate and temporary.

Common side effects

Drowsiness
Weight gain
Dizziness
Dry mouth
Constipation
Increased appetite
Orthostatic hypotension

While less common, some serious side effects may occur and require immediate medical attention.

Neuroleptic Malignant Syndrome (NMS)
Tardive Dyskinesia
High blood sugar (hyperglycemia)
Seizures
Blood dyscrasias

If you experience any persistent or severe side effects, or notice any unusual symptoms, contact your doctor immediately. Do not stop the medication without consulting your healthcare provider.

How to use OLENZATAS-5 TAB

Adults:
The usual starting dose for schizophrenia is 5-10 mg once daily, adjusted based on clinical response and tolerability, typically ranging from 5-20 mg/day. For bipolar mania, the starting dose is usually 10-15 mg once daily. Always follow your doctor's instructions precisely.
Children:
The use of Olanzapine in children and adolescents should be carefully considered and is generally not recommended below 13 years of age, except under specialist guidance due to potential risks and benefits. Dosage must be determined by a pediatric psychiatrist based on individual assessment.
Elderly:
Elderly patients may require a lower starting dose and slower titration due to increased sensitivity to side effects, particularly orthostatic hypotension and sedation. Close monitoring for adverse reactions and overall tolerability is essential in this population.
Missed Dose:
If you miss a dose of OLENZATAS-5 TAB, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one, as this can increase side effects.

How OLENZATAS-5 TAB works

Olanzapine, the active ingredient in OLENZATAS-5 TAB, exerts its therapeutic effects by acting on multiple neurotransmitter receptors in the brain. It primarily functions as an antagonist at dopamine D2 receptors and serotonin 5-HT2A receptors. By blocking these receptors, it helps to reduce the positive symptoms of schizophrenia, such as hallucinations and delusions, and also alleviates negative symptoms like social withdrawal and lack of motivation. Furthermore, Olanzapine also interacts with other receptors, including muscarinic M1, histamine H1, and alpha1-adrenergic receptors, contributing to its broader therapeutic profile and some of its side effects. This multi-receptor action helps in stabilizing mood in bipolar disorder and managing agitation, making it a versatile agent in neuropsychiatric care.

Precautions

Do not stop taking this medicine suddenly without consulting your doctor.
Monitor blood sugar levels regularly, especially if you have diabetes or risk factors for it.
Be cautious when driving or operating machinery as it may cause drowsiness or dizziness.
Avoid alcohol consumption as it can increase sedation and other central nervous system depressant effects.
Inform your doctor about all other medications you are taking to avoid potential drug interactions.
Report any unusual muscle movements, fever, or changes in mental status to your doctor immediately.

Safety Advice

Alcohol

UNSAFE

Avoid consuming alcohol while taking OLENZATAS-5 TAB. Alcohol can significantly increase the sedative effects of Olanzapine, leading to excessive drowsiness, dizziness, and impaired judgment, potentially worsening your condition.

Pregnancy

CONSULT YOUR DOCTOR

OLENZATAS-5 TAB should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Discuss with your doctor if you are pregnant or planning pregnancy, as careful consideration is required.

Breastfeeding

CONSULT YOUR DOCTOR

Olanzapine passes into breast milk and may affect the infant. It is advisable to consult your doctor to weigh the benefits of breastfeeding against the potential risks to the baby, and explore alternative feeding options if necessary.

Driving

UNSAFE

OLENZATAS-5 TAB can cause drowsiness, dizziness, and blurred vision, which may impair your ability to drive or operate heavy machinery safely. Avoid such activities until you know how the medicine affects you and are sure you can perform them safely.

Kidney

CAUTION

Patients with kidney disease should use OLENZATAS-5 TAB with caution. Dose adjustments may be necessary, and regular monitoring of kidney function is recommended by your doctor to ensure safe and effective treatment.

Liver

CAUTION

OLENZATAS-5 TAB should be used with caution in patients with liver impairment. Your doctor may need to adjust the dosage and monitor liver function tests regularly to prevent accumulation and potential adverse effects.

Fact Box

Chemical Class

Thienobenzodiazepine

Habit Forming

Therapeutic Class

Antipsychotic

Action Class

Dopamine and Serotonin Receptor Antagonist

Frequently asked questions by patients

Q: Can OLENZATAS-5 TAB be stopped suddenly?

A: No, stopping OLENZATAS-5 TAB suddenly can lead to withdrawal symptoms or a relapse of your condition. Always consult your doctor before making any changes to your medication regimen, as gradual tapering is usually recommended.

Q: Does OLENZATAS-5 TAB cause weight gain?

A: Yes, weight gain is a common side effect associated with Olanzapine. Your doctor may advise monitoring your weight and adopting a healthy lifestyle with diet and exercise to manage this potential side effect effectively.

Q: How long does it take for OLENZATAS-5 TAB to work?

A: While some improvements in symptoms may be noticed within a few days, the full therapeutic effects of OLENZATAS-5 TAB may take several weeks to become apparent. Continue taking it as prescribed, even if you don't feel immediate relief.

Q: Is OLENZATAS-5 TAB addictive?

A: No, OLENZATAS-5 TAB is not considered habit-forming or addictive. However, sudden discontinuation can lead to withdrawal-like symptoms, hence gradual tapering under medical supervision is advised to prevent adverse reactions.

Frequently Asked Questions

Q: What is OLENZATAS-5 TAB used for?

OLENZATAS-5 TAB is primarily used to treat schizophrenia and bipolar disorder. It helps manage symptoms like hallucinations, delusions, mood swings, and agitation by balancing certain chemicals in the brain, improving overall mental health and stability.

Q: What are the common side effects of OLENZATAS-5 TAB?

Common side effects include drowsiness, weight gain, dizziness, dry mouth, and constipation. These are usually mild and temporary, but consult your doctor if they persist or worsen, or if you experience any concerning symptoms.

Q: Can OLENZATAS-5 TAB affect my blood sugar?

Yes, Olanzapine can cause an increase in blood sugar levels, even in patients without a history of diabetes. Regular monitoring of blood sugar is recommended, especially for those at risk, and lifestyle modifications may be advised.

Q: Is it safe to drive after taking OLENZATAS-5 TAB?

No, it is generally not safe to drive or operate heavy machinery after taking OLENZATAS-5 TAB as it can cause significant drowsiness, dizziness, and impaired concentration. It is best to avoid such activities until you are certain of its effects on you.

Q: How should I store OLENZATAS-5 TAB?

Store OLENZATAS-5 TAB at room temperature, below 25°C, away from direct light and moisture. Keep it out of reach of children and pets to prevent accidental ingestion, and do not use it past its expiry date.