PRODUCT INTRODUCTION

OLENZATAS-10 TAB, containing Olanzapine 10mg, is an effective medication primarily used in the management of neurological and psychiatric conditions. It belongs to a class of drugs known as atypical antipsychotics, specifically formulated to help individuals suffering from schizophrenia and bipolar disorder. This medication works by restoring the balance of certain natural substances in the brain, thereby alleviating symptoms such as hallucinations, delusions, and severe mood swings. OLENZATAS-10 TAB is a crucial part of a comprehensive treatment plan, aiming to improve mental clarity, mood, and overall quality of life for patients in India. Always consult a healthcare professional for proper diagnosis and dosage guidance.

Uses of OLENZATAS-10 TAB

OLENZATAS-10 TAB is prescribed for the treatment of various mental health conditions, providing relief from severe symptoms and helping patients regain stability.

  • Schizophrenia

    OLENZATAS-10 TAB is highly effective in treating schizophrenia, a chronic mental disorder characterized by distorted thoughts, perceptions, emotions, language, sense of self, and behavior. It helps to reduce positive symptoms like hallucinations and delusions, as well as negative symptoms such as social withdrawal and lack of motivation, improving overall cognitive function and daily living.

  • Bipolar Disorder (Manic or Mixed Episodes)

    This medication is used to manage acute manic or mixed episodes associated with bipolar I disorder. Manic episodes involve abnormally elevated mood, increased energy, racing thoughts, and decreased need for sleep, while mixed episodes involve symptoms of both mania and depression. OLENZATAS-10 TAB helps to stabilize mood and reduce the intensity of these episodes.

  • Maintenance Treatment of Bipolar Disorder

    OLENZATAS-10 TAB is also indicated for the long-term maintenance treatment of bipolar I disorder. By preventing the recurrence of manic, mixed, or depressive episodes, it helps patients maintain mood stability over time, significantly improving their quality of life and reducing the frequency of hospitalizations.

Side Effects of OLENZATAS-10 TAB

Like all medications, OLENZATAS-10 TAB can cause side effects, although not everybody gets them. Most side effects are mild to moderate and temporary. It's important to discuss any concerns with your doctor.

Common side effects

  • Weight gain
  • Drowsiness
  • Dry mouth
  • Dizziness
  • Constipation
  • Increased appetite
  • Orthostatic hypotension
  • Restlessness

While less common, some serious side effects can occur. Seek immediate medical attention if you experience any of these.

  • Tardive dyskinesia (involuntary movements)
  • Neuroleptic Malignant Syndrome (fever, muscle rigidity, altered mental status)
  • Hyperglycemia (high blood sugar)
  • Seizures
  • Pancreatitis

If any side effect bothers you or persists, please consult your doctor. Do not stop the medication without consulting your healthcare provider.

How to use OLENZATAS-10 TAB

  • Adults:

    For schizophrenia, the usual starting dose is 10 mg once daily. For bipolar mania, the starting dose is typically 10-15 mg once daily. Doses may be adjusted based on clinical response and tolerability, usually ranging from 5 mg to 20 mg per day. It can be taken with or without food.

  • Children:

    The safety and efficacy of Olanzapine in children and adolescents under 18 years of age have not been fully established. Its use in this population is generally not recommended unless specifically advised by a specialist, considering potential risks and benefits.

  • Elderly:

    A lower starting dose of 5 mg once daily may be considered for elderly patients, especially those with predisposing factors for adverse reactions. Close monitoring for side effects, particularly sedation and orthostatic hypotension, is crucial. Dose adjustments should be gradual and based on individual response.

  • Missed Dose:

    If you miss a dose of OLENZATAS-10 TAB, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one, as this can increase the risk of side effects.

How OLENZATAS-10 TAB works

Olanzapine, the active ingredient in OLENZATAS-10 TAB, exerts its therapeutic effects by acting on multiple neurotransmitter receptors in the brain. It primarily functions as an antagonist at dopamine D2 receptors and serotonin 5-HT2A receptors. By blocking these receptors, Olanzapine helps to regulate the activity of dopamine and serotonin, which are key neurotransmitters implicated in mood, cognition, and behavior. The antagonism of D2 receptors is believed to be responsible for its antipsychotic effects, reducing positive symptoms of schizophrenia like hallucinations and delusions. Simultaneously, its strong antagonism of 5-HT2A receptors, coupled with its action on other serotonin receptors (5-HT2C, 5-HT3, 5-HT6), contributes to its efficacy against negative symptoms of schizophrenia and its mood-stabilizing properties in bipolar disorder. Furthermore, Olanzapine also has antagonistic effects on alpha-1 adrenergic, histamine H1, and muscarinic M1 receptors, which contribute to some of its side effects such as orthostatic hypotension, sedation, and anticholinergic effects like dry mouth and constipation. This multi-receptor profile allows OLENZATAS-10 TAB to offer broad-spectrum relief for complex psychiatric conditions.

Precautions

  • Monitor for signs of hyperglycemia and diabetes, especially in patients with risk factors.
  • Use with caution in patients with known cardiovascular disease, cerebrovascular disease, or conditions predisposing to hypotension.
  • Patients with a history of seizures or conditions that lower the seizure threshold should be closely monitored.
  • Exercise caution in patients with hepatic or renal impairment; dose adjustment may be necessary.
  • Risk of tardive dyskinesia increases with long-term use; discontinue if symptoms appear.
  • Avoid sudden discontinuation of OLENZATAS-10 TAB, as it can lead to withdrawal symptoms or relapse.
  • May cause sedation and orthostatic hypotension; advise patients to be cautious when driving or operating machinery.
  • Regular monitoring of weight, blood glucose, and lipid profiles is recommended during treatment.

Safety Advice

Alcohol

Alcohol

UNSAFE

Consuming alcohol while taking OLENZATAS-10 TAB can significantly increase drowsiness and dizziness, impairing your judgment and coordination. It is strongly advised to avoid alcohol during treatment.

Pregnancy

Pregnancy

CONSULT YOUR DOCTOR

The use of OLENZATAS-10 TAB during pregnancy should only be considered if the potential benefit justifies the potential risk to the fetus. Consult your doctor to discuss the risks and benefits before taking this medication.

Breastfeeding

Breastfeeding

CONSULT YOUR DOCTOR

Olanzapine is excreted into breast milk and may cause adverse effects in a nursing infant. It is advisable to consult your doctor to weigh the benefits of breastfeeding against the potential risks to the baby.

Driving

Driving

UNSAFE

OLENZATAS-10 TAB can cause drowsiness, dizziness, and blurred vision, which may impair your ability to drive or operate machinery safely. Avoid driving or engaging in activities requiring mental alertness until you know how the medication affects you.

Kidney

Kidney

CAUTION

Patients with kidney impairment should use OLENZATAS-10 TAB with caution. Dose adjustments may be necessary based on the severity of renal dysfunction. Always consult your doctor for personalized advice.

Liver

Liver

CAUTION

OLENZATAS-10 TAB should be used with caution in patients with liver disease. Your doctor may need to adjust the dosage and monitor liver function regularly to prevent adverse effects.

Fact Box

Chemical Class
Thienobenzodiazepine
Habit Forming
No
Therapeutic Class
Antipsychotic
Action Class
Dopamine and Serotonin Receptor Antagonist

Frequently asked questions by patients

Q: How long does OLENZATAS-10 TAB take to show its effects?

A: While some improvement in symptoms like agitation or sleep may be noticed within a few days, the full therapeutic effects of OLENZATAS-10 TAB, especially for conditions like schizophrenia and bipolar disorder, may take several weeks to become apparent. Consistent use as prescribed is crucial for optimal results.

Q: Can I stop taking OLENZATAS-10 TAB if I feel better?

A: No, you should not stop taking OLENZATAS-10 TAB suddenly, even if you feel better. Abrupt discontinuation can lead to withdrawal symptoms or a relapse of your condition. Always consult your doctor before making any changes to your medication regimen.

Q: Will OLENZATAS-10 TAB make me gain weight?

A: Weight gain is a common side effect associated with Olanzapine. It's important to monitor your weight regularly and discuss strategies with your doctor or a dietitian to manage this, such as maintaining a balanced diet and engaging in regular physical activity.

Q: Is OLENZATAS-10 TAB safe for long-term use?

A: OLENZATAS-10 TAB is often prescribed for long-term management of chronic conditions like schizophrenia and bipolar disorder. Your doctor will regularly assess your condition and monitor for any long-term side effects, such as metabolic changes or tardive dyskinesia, to ensure its continued safety and efficacy.

Frequently Asked Questions

Q: What is OLENZATAS-10 TAB primarily used for?

OLENZATAS-10 TAB, containing Olanzapine 10mg, is primarily used to treat schizophrenia and bipolar disorder. It helps manage symptoms like hallucinations, delusions, and severe mood swings by balancing certain natural substances in the brain. It's an important medication for improving mental stability and quality of life.

Q: How should I take OLENZATAS-10 TAB?

You should take OLENZATAS-10 TAB exactly as prescribed by your doctor. It can be taken with or without food, usually once daily. Do not chew, crush, or break the tablet. Adhere strictly to the prescribed dosage and schedule for the best therapeutic outcomes.

Q: What are the common side effects of OLENZATAS-10 TAB?

Common side effects include weight gain, drowsiness, dry mouth, dizziness, increased appetite, and constipation. These are usually mild and temporary. If any of these persist or worsen, it is important to consult your doctor for advice and management.

Q: Can OLENZATAS-10 TAB be taken with other medications?

It is crucial to inform your doctor about all other medications, including over-the-counter drugs, herbal supplements, and vitamins, you are currently taking. OLENZATAS-10 TAB can interact with certain medications, potentially altering their effects or increasing the risk of side effects. Your doctor will assess potential interactions.

Q: What should I do if I experience severe side effects?

If you experience any severe or unusual side effects such as involuntary movements (tardive dyskinesia), high fever with muscle rigidity (neuroleptic malignant syndrome), or signs of severe allergic reaction, seek immediate medical attention. Do not hesitate to contact your doctor or emergency services.

Additional Information

Category
Neurological
FORM
TABLET
Tag
Atypical Antipsychotic
Packing
10*10
Composition
OLANZAPINE 10MG
Disclaimer: This information is provided for educational purposes only and should not replace professional medical advice. Always consult your healthcare provider before starting, stopping, or changing any medication. Individual results may vary. Keep this and all medications out of reach of children.

OLENZATAS-10 TAB, with its active ingredient Olanzapine 10mg, stands as a vital medication in the therapeutic landscape for managing complex neurological conditions such as schizophrenia and bipolar disorder. By carefully modulating dopamine and serotonin pathways in the brain, it effectively addresses symptoms like hallucinations, delusions, and mood instability, offering patients a path towards greater mental clarity and emotional equilibrium. Its role extends beyond acute symptom management to long-term maintenance, significantly enhancing the quality of life and reducing the likelihood of relapse for individuals living with these challenging conditions. Adherence to the prescribed dosage and regular follow-ups with a healthcare professional are paramount to ensure optimal therapeutic benefits and to monitor for any potential side effects. While common side effects like weight gain and drowsiness are manageable, awareness of rarer, more serious adverse events is crucial for timely intervention. OLENZATAS-10 TAB represents a significant advancement in psychiatric care, providing a reliable option for patients and clinicians dedicated to achieving sustained mental well-being. Always remember that this medication requires a prescription and should be used under strict medical supervision.

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