NORFAX TZ TAB

Uses of NORFAX TZ TAB

NORFAX TZ TAB is prescribed for the treatment of various bacterial and protozoal infections. It is particularly effective in conditions where both types of pathogens may be involved.

• Bacterial Diarrhea and Dysentery

  This medication is highly effective in treating acute bacterial diarrhea and dysentery caused by susceptible organisms. Norfloxacin targets bacterial pathogens, while Tinidazole helps manage any co-existing protozoal infections, providing comprehensive relief from symptoms like loose stools, abdominal cramps, and fever.

• Amoebiasis

  NORFAX TZ TAB is used to treat amoebic infections, including intestinal amoebiasis (amoebic dysentery) and hepatic amoebiasis (amoebic liver abscess). Tinidazole, a key component, is particularly effective against Entamoeba histolytica, the parasite responsible for these conditions, helping to eradicate the infection.

• Giardiasis

  Giardiasis, an intestinal infection caused by the parasite Giardia lamblia, can be effectively managed with NORFAX TZ TAB. Tinidazole targets and eliminates the Giardia parasites, reducing symptoms such as abdominal pain, bloating, nausea, and watery diarrhea, leading to a faster recovery.

Side Effects of NORFAX TZ TAB

Like all medications, NORFAX TZ TAB can cause side effects, although not everyone experiences them. Most side effects are mild to moderate and temporary.

Less common but potentially serious side effects require immediate medical attention. If you experience any of these, contact your doctor promptly.

If any side effect persists or worsens, or if you experience any other unusual symptoms, consult your doctor immediately. Do not discontinue the medication without medical advice.

How to use NORFAX TZ TAB

• Adults:

  Typically, one tablet of NORFAX TZ TAB is taken twice daily, preferably after meals, or as directed by the physician. The duration of treatment usually ranges from 5 to 7 days, depending on the type and severity of the infection. It is crucial to complete the entire prescribed course even if symptoms improve.

• Children:

  The use of NORFAX TZ TAB in children should be strictly under medical supervision. Pediatric dosage will be determined by a doctor based on the child's age, weight, and the specific infection being treated. Self-medication in children is not recommended.

• Elderly:

  Elderly patients may require dose adjustments, especially if they have impaired kidney or liver function. A doctor should assess the patient's overall health and co-existing conditions before prescribing NORFAX TZ TAB to ensure safety and efficacy.

• Missed Dose:

  If you miss a dose of NORFAX TZ TAB, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.

How NORFAX TZ TAB works

NORFAX TZ TAB exerts its therapeutic effects through the distinct yet complementary mechanisms of its two active components. Norfloxacin, a potent fluoroquinolone antibiotic, works by inhibiting bacterial DNA gyrase and topoisomerase IV, essential enzymes involved in bacterial DNA replication, transcription, repair, and recombination. This leads to disruption of bacterial DNA synthesis and ultimately, bacterial cell death, making it bactericidal. Tinidazole, a nitroimidazole derivative, acts by entering microbial cells, where it is reduced to active metabolites. These metabolites then interact with and damage the DNA and other macromolecules of susceptible anaerobic bacteria and protozoa. This damage inhibits nucleic acid synthesis, leading to the death of the infectious organisms. The combination of Norfloxacin and Tinidazole provides broad-spectrum coverage against both aerobic and anaerobic bacteria, as well as various protozoal parasites, making NORFAX TZ TAB highly effective against complex infections.

Precautions

• Avoid alcohol consumption during and for at least 3 days after treatment with Tinidazole due to disulfiram-like reaction.
• Use with caution in patients with a history of central nervous system (CNS) disorders like epilepsy or seizures.
• Patients should avoid excessive exposure to sunlight or artificial UV light as Norfloxacin can cause photosensitivity.
• Exercise caution in patients with kidney or liver impairment; dose adjustment may be necessary.
• Discontinue treatment if you experience pain, swelling, or inflammation of a tendon, especially in the elderly or those on corticosteroids.
• Inform your doctor about all other medications you are taking to avoid potential drug interactions.

Safety Advice

Alcohol

UNSAFE

It is unsafe to consume alcohol while taking NORFAX TZ TAB and for at least 3 days after the last dose. Tinidazole can cause a disulfiram-like reaction, leading to symptoms like flushing, nausea, vomiting, and headache.

Pregnancy

UNSAFE

NORFAX TZ TAB is generally considered unsafe during pregnancy, especially in the first trimester. Consult your doctor immediately if you are pregnant or planning a pregnancy. The doctor will weigh the benefits against the potential risks.

Breastfeeding

UNSAFE

NORFAX TZ TAB is not recommended during breastfeeding as both Norfloxacin and Tinidazole can pass into breast milk and may harm the infant. Consult your doctor for alternative treatment options or advice on breastfeeding.

Driving

CAUTION

NORFAX TZ TAB may cause dizziness, lightheadedness, or visual disturbances in some individuals. If you experience these symptoms, avoid driving or operating heavy machinery until you know how the medication affects you.

Kidney

CAUTION

Patients with kidney disease should use NORFAX TZ TAB with caution. Dose adjustment may be necessary based on kidney function. Always consult your doctor before taking this medication if you have any kidney issues.

Liver

CAUTION

Individuals with liver disease should use NORFAX TZ TAB with caution. The liver metabolizes medications, and impaired liver function may affect drug clearance. Your doctor may adjust the dosage or recommend alternative treatments.

Fact Box

Frequently asked questions by patients

Frequently Asked Questions

Additional Information