PRODUCT INTRODUCTION

CEFURACTUM-500 TAB, containing Cefuroxime Axetil 500mg, is a potent antibiotic widely used in India to combat a variety of bacterial infections. As a second-generation cephalosporin, it effectively targets and eliminates harmful bacteria, providing relief from symptoms and promoting recovery. This medication is crucial for treating conditions like respiratory tract infections, skin and soft tissue infections, and urinary tract infections. Its broad-spectrum activity makes it a reliable choice for healthcare professionals seeking to manage bacterial illnesses effectively. Always use CEFURACTUM-500 TAB under medical supervision to ensure optimal outcomes and prevent antibiotic resistance.

Uses of CEFURACTUM-500 TAB

CEFURACTUM-500 TAB is prescribed for the treatment of various bacterial infections affecting different parts of the body.

  • Respiratory Tract Infections

    Effective in treating bacterial infections of the respiratory system, including bronchitis, pneumonia, and sinusitis. It helps alleviate symptoms like cough, fever, and difficulty breathing by targeting the causative bacteria and promoting recovery.

  • Skin and Soft Tissue Infections

    Used for bacterial skin infections such as cellulitis, impetigo, and wound infections. It works by eliminating the bacteria responsible for inflammation, redness, and pain, promoting faster healing of affected areas and preventing spread.

  • Urinary Tract Infections

    Prescribed for uncomplicated urinary tract infections (UTIs) caused by susceptible bacteria. It helps clear the infection, reducing symptoms like painful urination, frequent urges, and lower abdominal discomfort, restoring urinary comfort.

  • Ear, Nose, and Throat Infections

    Beneficial in treating conditions like otitis media (middle ear infection) and pharyngitis/tonsillitis caused by bacterial pathogens. It helps reduce inflammation and pain, leading to quicker recovery and preventing complications in these sensitive areas.

Side Effects of CEFURACTUM-500 TAB

Like all medicines, CEFURACTUM-500 TAB can cause side effects, although not everybody gets them. Most side effects are mild and temporary.

Common side effects

  • Diarrhea
  • Nausea
  • Vomiting
  • Abdominal pain
  • Headache
  • Dizziness

Seek immediate medical attention if you experience any of the following rare but serious side effects.

  • Severe allergic reactions (rash, itching, swelling, severe dizziness, trouble breathing)
  • Clostridium difficile-associated diarrhea (severe or persistent diarrhea)
  • Liver problems (yellowing of skin/eyes)
  • Kidney problems

If any of these side effects persist or worsen, or if you notice any other unusual symptoms, please consult your doctor immediately for advice and management.

How to use CEFURACTUM-500 TAB

  • Adults:

    Typically, 250 mg to 500 mg twice daily, depending on the severity and type of infection. It should be taken after food for optimal absorption. The duration of treatment varies but is usually 5-10 days, as directed by the physician.

  • Children:

    Dosage is determined by body weight and the severity of the infection, usually 10-15 mg/kg twice daily, up to a maximum adult dose. Always consult a pediatrician for precise dosing instructions and administration guidance.

  • Elderly:

    No specific dose adjustment is usually required unless there is significant renal impairment. Close monitoring of kidney function is advised in elderly patients to ensure safe and effective use of the medication.

  • Missed Dose:

    If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up, as this may increase side effects.

How CEFURACTUM-500 TAB works

Cefuroxime Axetil, the active ingredient in CEFURACTUM-500 TAB, belongs to the cephalosporin class of antibiotics. Its primary mechanism of action involves inhibiting bacterial cell wall synthesis. Bacteria rely on a robust cell wall for their structural integrity and survival. Cefuroxime Axetil achieves its bactericidal effect by binding to penicillin-binding proteins (PBPs) located within the bacterial cell wall. By binding to these PBPs, Cefuroxime Axetil prevents the cross-linking of peptidoglycan units, which are essential components of the bacterial cell wall. This disruption leads to a weakened and permeable cell wall, ultimately causing the bacterial cell to lyse and die. Cefuroxime Axetil is effective against a wide range of gram-positive and gram-negative bacteria, making it a versatile option for treating diverse infections. Its axetil ester form enhances oral absorption, ensuring good bioavailability.

Precautions

  • Inform your doctor if you have a history of allergies to penicillin or other cephalosporin antibiotics.
  • Use with caution in patients with a history of gastrointestinal disease, especially colitis.
  • Prolonged use may result in the overgrowth of non-susceptible organisms, including fungi.
  • Monitor kidney function in patients with pre-existing renal impairment.
  • May interfere with certain laboratory tests, such as Coombs' test.
  • Complete the full course of treatment even if you feel better to prevent recurrence and antibiotic resistance.

Safety Advice

Alcohol

Alcohol

CAUTION

It is generally advisable to limit or avoid alcohol consumption while taking CEFURACTUM-500 TAB as it may increase the risk of side effects like dizziness and stomach upset. Consult your doctor for personalized advice.

Pregnancy

Pregnancy

CONSULT YOUR DOCTOR

CEFURACTUM-500 TAB should be used during pregnancy only if clearly needed and after consulting your doctor. Your doctor will weigh the potential benefits against the risks to the unborn baby before prescribing.

Breastfeeding

Breastfeeding

CONSULT YOUR DOCTOR

Small amounts of Cefuroxime Axetil may pass into breast milk. Consult your doctor before breastfeeding while taking this medication to assess potential risks to the infant and determine the best course of action.

Driving

Driving

SAFE

CEFURACTUM-500 TAB generally does not impair your ability to drive or operate machinery. However, if you experience dizziness or other side effects that affect your concentration, avoid such activities.

Kidney

Kidney

CAUTION

Dose adjustment may be necessary in patients with severe kidney impairment. Inform your doctor about any kidney problems, as they may need to modify your dosage and monitor kidney function closely.

Liver

Liver

SAFE IF PRESCRIBED

CEFURACTUM-500 TAB is generally safe for patients with liver disease. However, if you have severe liver conditions, consult your doctor for appropriate guidance and monitoring to ensure no adverse effects occur.

Fact Box

Chemical Class
Cephalosporin Antibiotic
Habit Forming
No
Therapeutic Class
Antibacterial
Action Class
Bactericidal

Frequently asked questions by patients

Q: Can I stop taking CEFURACTUM-500 TAB once my symptoms improve?

A: No, it is crucial to complete the full course of CEFURACTUM-500 TAB as prescribed by your doctor, even if your symptoms improve. Stopping early can lead to the infection returning and may contribute to antibiotic resistance, making future treatments less effective.

Q: What should I do if I experience an allergic reaction to CEFURACTUM-500 TAB?

A: If you experience signs of an allergic reaction such as rash, itching, swelling (especially of the face/throat), severe dizziness, or trouble breathing, seek immediate medical attention. Inform your doctor about any known allergies before starting treatment to prevent such reactions.

Q: Does CEFURACTUM-500 TAB cause stomach upset?

A: Yes, common side effects can include stomach upset, nausea, vomiting, or diarrhea. Taking the tablet with food can help minimize these gastrointestinal disturbances. If symptoms are severe or persistent, consult your doctor for advice.

Q: Is CEFURACTUM-500 TAB safe for children?

A: CEFURACTUM-500 TAB can be prescribed for children, but the dosage must be carefully determined by a pediatrician based on the child's weight and the specific infection. Always follow the doctor's instructions for pediatric dosing precisely.

Frequently Asked Questions

Q: How quickly does CEFURACTUM-500 TAB start working?

You may start to feel better within a few days of starting CEFURACTUM-500 TAB, but the full effects of the antibiotic may take longer. It's important to continue the medication for the entire prescribed duration to ensure complete eradication of the infection and prevent recurrence.

Q: Can CEFURACTUM-500 TAB be taken with other medications?

It's important to inform your doctor about all other medications you are currently taking, including over-the-counter drugs and herbal supplements, to avoid potential drug interactions. Certain medications, like antacids or oral contraceptives, may interact with Cefuroxime Axetil, affecting its efficacy or increasing side effects.

Q: What is the difference between Cefuroxime Axetil and other antibiotics?

Cefuroxime Axetil is a second-generation cephalosporin antibiotic, meaning it has a broader spectrum of activity against both Gram-positive and Gram-negative bacteria compared to first-generation cephalosporins. Its specific chemical structure gives it efficacy against certain resistant strains, making it suitable for a wider range of infections.

Q: Can CEFURACTUM-500 TAB be used for viral infections?

No, CEFURACTUM-500 TAB is an antibiotic and is specifically designed to treat bacterial infections. It is not effective against viral infections like the common cold or flu. Using antibiotics unnecessarily for viral infections can lead to antibiotic resistance, making them less effective when truly needed.

Q: What should I do if I forget to take a dose of CEFURACTUM-500 TAB?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a forgotten one, as this can increase the risk of side effects.

Additional Information

Category
Antibiotics
FORM
TABLET
Tag
Second-generation Cephalosporin, Broad-spectrum antibiotic
Packing
10x1x10
Composition
CEFUROXINE AXETIL 500MG
Disclaimer: This information is provided for educational purposes only and should not replace professional medical advice. Always consult your healthcare provider before starting, stopping, or changing any medication. Individual results may vary. Keep this and all medications out of reach of children.

CEFURACTUM-500 TAB, containing Cefuroxime Axetil 500mg, stands as a vital broad-spectrum antibiotic in the fight against various bacterial infections. Its efficacy in treating respiratory tract, skin, urinary tract, and ENT infections makes it a trusted choice for healthcare professionals across India. By inhibiting bacterial cell wall synthesis, it effectively eradicates harmful pathogens, leading to symptom relief and faster recovery. Patients are advised to adhere strictly to the prescribed dosage and complete the full course of treatment to ensure optimal outcomes and minimize the risk of antibiotic resistance. While generally well-tolerated, awareness of potential side effects and precautions is essential. Always consult your doctor for personalized medical advice, especially regarding dosage adjustments, potential interactions, and use during pregnancy or breastfeeding. CEFURACTUM-500 TAB plays a significant role in promoting public health by providing an effective solution for bacterial illnesses. This information is intended for general knowledge and informational purposes only, and does not constitute medical advice. Always consult with a qualified healthcare professional for any health concerns or before making any decisions related to your health or treatment.

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