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Antibiotics
METROTAS-400MG TAB
SALT COMPOSITION
METRONIDAZOLE 400MGTYPE
TABLET
STORAGE
Store METROTAS-400MG TAB below 30°C in a cool, dry place, protected from light and moisture. Keep out of reach of children and pets to prevent accidental ingestion.
PRODUCT INTRODUCTION
METROTAS-400MG TAB is a potent antimicrobial medication widely prescribed in India for treating a variety of bacterial and parasitic infections. Containing Metronidazole 400mg, this tablet is highly effective against anaerobic bacteria and certain protozoa, making it a crucial drug in combating conditions like amoebiasis, giardiasis, and bacterial vaginosis. It is a trusted choice for healthcare professionals due to its broad spectrum of activity and established efficacy. Always use METROTAS-400MG TAB under medical supervision to ensure proper dosage and treatment duration for optimal results and to prevent resistance.
Uses of METROTAS-400MG TAB
METROTAS-400MG TAB is primarily used to treat infections caused by anaerobic bacteria and certain parasites, offering relief from various conditions.
- Bacterial Vaginosis
A common vaginal infection caused by an overgrowth of certain bacteria. Metrotas-400mg effectively restores the natural balance of bacteria in the vagina, alleviating symptoms like unusual discharge, odor, and itching. Treatment typically involves a course of tablets as prescribed by a doctor to ensure complete eradication of the infection and prevent recurrence.
- Amoebiasis
An intestinal infection caused by the parasite Entamoeba histolytica. Metrotas-400mg targets and kills the amoebae in the intestines and other tissues, treating symptoms such as diarrhea, abdominal pain, and fever. It is crucial to complete the full course of treatment to prevent relapse and ensure the parasite is fully eliminated from the body.
- Giardiasis
An intestinal infection caused by the parasite Giardia lamblia. Metrotas-400mg is highly effective in eradicating Giardia, reducing symptoms like watery diarrhea, abdominal cramps, and nausea. This medication helps in clearing the parasitic load, improving digestive health, and preventing the spread of the infection to others, ensuring comprehensive recovery.
- Trichomoniasis
A sexually transmitted infection caused by the parasite Trichomonas vaginalis. Metrotas-400mg is a frontline treatment, effectively eliminating the parasite in both men and women, thereby resolving symptoms like itching, burning, and unusual discharge. Both partners should be treated simultaneously to prevent re-infection and ensure complete eradication of the parasite.
Side Effects of METROTAS-400MG TAB
Like all medicines, METROTAS-400MG TAB can cause side effects, although not everybody gets them. Most side effects are mild and temporary and usually resolve after treatment.
Common side effects
- Nausea
- Vomiting
- Diarrhea
- Metallic taste in mouth
- Headache
- Dizziness
- Abdominal cramps
Seek immediate medical attention if you experience any of these rare but serious side effects, as they may require urgent medical intervention.
- Severe allergic reactions (rash, itching, swelling)
- Seizures
- Peripheral neuropathy (numbness, tingling)
- Dark urine
If any side effect bothers you or persists, please consult your doctor promptly. Do not stop taking the medication without medical advice, as this could lead to a relapse of the infection.
How to use METROTAS-400MG TAB
- Adults:
The typical adult dosage for most infections is 400mg to 800mg, two to three times daily, depending on the severity and type of infection. Treatment duration usually ranges from 5 to 10 days. For specific conditions like amoebiasis, a higher dose or longer duration might be prescribed. Always follow your doctor's instructions precisely and do not alter the dosage.
- Children:
Dosage for children is determined by body weight and the specific infection being treated. It is crucial to consult a pediatrician for accurate dosing. Generally, it can range from 7.5mg/kg to 15mg/kg, three times a day. Do not self-medicate children with Metrotas-400mg; always seek professional medical advice for pediatric patients.
- Elderly:
Elderly patients may require dosage adjustments due to potential age-related decline in kidney or liver function. Close monitoring for side effects is recommended. Your doctor will assess your overall health and adjust the dose accordingly to minimize risks and ensure safe and effective treatment.
- Missed Dose:
If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one, as this can increase the risk of side effects and is not recommended.
How METROTAS-400MG TAB works
Metronidazole, the active ingredient in METROTAS-400MG TAB, works by entering the cells of susceptible anaerobic bacteria and protozoa. Once inside, it undergoes a chemical reduction, forming highly reactive nitro-free radicals. These free radicals disrupt the DNA structure of the pathogens, inhibiting nucleic acid synthesis and leading to cell death. This unique mechanism of action makes Metronidazole particularly effective against organisms that thrive in low-oxygen environments. Its selective toxicity ensures minimal harm to human cells while effectively eradicating the infection, making it a powerful tool against various microbial threats.
Precautions
- Avoid alcohol consumption during and for at least 3 days after treatment due to disulfiram-like reaction.
- Inform your doctor if you have liver disease, kidney disease, or Crohn's disease before starting treatment.
- Use with caution in patients with central nervous system disorders, as it may exacerbate symptoms.
- Prolonged use may lead to peripheral neuropathy or seizures; monitor symptoms and report to your doctor.
- May interfere with certain lab tests, so inform your doctor or lab personnel that you are taking Metronidazole.
- Complete the full course of treatment even if symptoms improve to prevent resistance and recurrence of the infection.
Safety Advice
Alcohol
UNSAFEAvoid alcohol completely during treatment with METROTAS-400MG TAB and for at least 3 days after stopping. Combining metronidazole with alcohol can cause severe reactions like nausea, vomiting, flushing, and headache, known as a disulfiram-like reaction.
Pregnancy
CONSULT YOUR DOCTORMETROTAS-400MG TAB should be used during pregnancy only if clearly needed and prescribed by a doctor, especially during the first trimester. Discuss the potential risks and benefits with your healthcare provider to ensure the best outcome for you and your baby.
Breastfeeding
CONSULT YOUR DOCTORMetronidazole passes into breast milk. It is advisable to consult your doctor before breastfeeding while taking METROTAS-400MG TAB. Your doctor may suggest temporarily stopping breastfeeding or an alternative treatment to ensure infant safety.
Driving
CAUTIONMETROTAS-400MG TAB may cause dizziness or drowsiness in some individuals. If you experience these symptoms, avoid driving or operating heavy machinery until you know how the medication affects you and are sure you can perform these activities safely.
Kidney
CAUTIONPatients with severe kidney disease may require a dose adjustment of METROTAS-400MG TAB. Consult your doctor, who will assess your kidney function and determine the appropriate dosage to prevent drug accumulation and potential adverse effects.
Liver
CAUTIONMETROTAS-400MG TAB is metabolized in the liver. Patients with severe liver impairment may need a reduced dose. Your doctor will monitor your liver function closely during treatment to ensure safety and adjust the dosage as necessary.
Fact Box
Frequently asked questions by patients
Q: Can I stop taking METROTAS-400MG TAB if I feel better?
A: No, it is crucial to complete the full course of METROTAS-400MG TAB as prescribed by your doctor, even if your symptoms improve. Stopping early can lead to the infection returning and potentially developing antibiotic resistance, making future treatments less effective.
Q: What should I do if I experience a metallic taste in my mouth?
A: A metallic taste is a common side effect of Metronidazole and is usually temporary. It typically resolves after you stop the medication. If it is bothersome, try chewing sugar-free gum or mints, or discuss it with your doctor for possible remedies or reassurance.
Q: Is METROTAS-400MG TAB effective against viral infections?
A: No, METROTAS-400MG TAB is an antibiotic and anti-protozoal medication. It is specifically designed to treat bacterial and parasitic infections and will not be effective against viral infections like the common cold or flu. Using it for viral infections can contribute to antibiotic resistance.
Q: Can METROTAS-400MG TAB be taken with food?
A: Yes, it is generally recommended to take METROTAS-400MG TAB with food or a glass of milk to minimize stomach upset, nausea, or abdominal discomfort. Always follow your doctor's specific instructions regarding administration for optimal absorption and reduced side effects.
Frequently Asked Questions
Q: What is METROTAS-400MG TAB used for?
METROTAS-400MG TAB, containing Metronidazole 400mg, is primarily used to treat a wide range of bacterial and parasitic infections. This includes conditions like bacterial vaginosis, amoebiasis, giardiasis, trichomoniasis, and various anaerobic bacterial infections affecting the gastrointestinal tract, skin, and other body systems. Always consult a doctor for proper diagnosis and treatment before use.
Q: How long does it take for METROTAS-400MG TAB to work?
The onset of action for METROTAS-400MG TAB can vary depending on the type and severity of the infection. Many patients start to feel better within a few days of starting treatment. However, it is essential to complete the entire prescribed course to ensure complete eradication of the infection and prevent recurrence or the development of drug resistance.
Q: Are there any dietary restrictions while taking METROTAS-400MG TAB?
The most important dietary restriction while taking METROTAS-400MG TAB is to strictly avoid alcohol and alcohol-containing products. Consuming alcohol can lead to a severe disulfiram-like reaction, causing symptoms like nausea, vomiting, flushing, and headaches. Otherwise, no specific food restrictions are typically advised, but taking it with food can reduce stomach upset.
Q: What if I am pregnant or breastfeeding and need to take METROTAS-400MG TAB?
If you are pregnant or breastfeeding, it is crucial to inform your doctor before taking METROTAS-400MG TAB. While it may be prescribed in certain situations, especially after the first trimester, your doctor will weigh the potential benefits against the risks and decide if it's the most appropriate treatment for you. They may also suggest alternative options or close monitoring.
Q: Can METROTAS-400MG TAB cause dark urine?
Yes, a harmless side effect of Metronidazole, the active ingredient in METROTAS-400MG TAB, can be a darkening of the urine. This is due to a metabolite of the drug and is generally not a cause for concern. If you notice other unusual changes in urine color or experience discomfort, pain, or fever, consult your doctor to rule out other issues.
Additional Information
METROTAS-400MG TAB, powered by Metronidazole 400mg, stands as a vital antimicrobial agent in the Indian pharmaceutical landscape, effectively combating a spectrum of bacterial and parasitic infections. Its targeted action against anaerobic bacteria and specific protozoa makes it indispensable for treating conditions ranging from gastrointestinal infections like amoebiasis and giardiasis to gynecological issues such as bacterial vaginosis and trichomoniasis. Adherence to the prescribed dosage and completion of the full treatment course are paramount to ensure optimal therapeutic outcomes and prevent the development of drug resistance, which is a growing concern in public health. Patients are advised to be aware of potential side effects, particularly the strong interaction with alcohol, and to consult their healthcare provider for any concerns or persistent symptoms. With its established efficacy and broad utility, METROTAS-400MG TAB continues to be a trusted choice for healthcare professionals seeking reliable solutions for infectious diseases, contributing significantly to public health in India. Always remember to use this medication under strict medical supervision and never self-medicate.
