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Cardiovascular
LOSARVAS-50 TAB
SALT COMPOSITION
LOSARTAN POTASSIUM 50MGTYPE
TABLET
STORAGE
Store LOSARVAS-50 TAB below 30°C in a cool, dry place, away from direct sunlight and moisture. Keep out of reach of children and pets.
PRODUCT INTRODUCTION
LOSARVAS-50 TAB, containing Losartan Potassium 50mg, is a widely prescribed medication in India for managing high blood pressure (hypertension). As an Angiotensin Receptor Blocker (ARB), it works by relaxing blood vessels, allowing blood to flow more easily. This not only helps in lowering elevated blood pressure but also significantly reduces the risk of serious cardiovascular events such as heart attacks and strokes. It is also beneficial for patients with heart failure and those with type 2 diabetes who have kidney problems (diabetic nephropathy). Always consult your doctor for proper diagnosis and dosage, as LOSARVAS-50 TAB is a prescription-only medicine.
Uses of LOSARVAS-50 TAB
LOSARVAS-50 TAB is prescribed for several cardiovascular conditions to improve patient outcomes and quality of life.
- Hypertension (High Blood Pressure)
LOSARVAS-50 TAB is highly effective in treating essential hypertension. It helps to lower elevated blood pressure, reducing the strain on the heart and blood vessels. Regular use, as prescribed, can prevent complications such as stroke, heart attack, and kidney damage associated with chronic high blood pressure.
- Heart Failure
This medication is also used in the management of heart failure, particularly when ACE inhibitors are not tolerated. By reducing the workload on the heart and improving blood flow, LOSARVAS-50 TAB helps to alleviate symptoms like shortness of breath and swelling, enhancing the heart's pumping efficiency and improving overall patient well-being.
- Diabetic Nephropathy
LOSARVAS-50 TAB is indicated for the protection of kidney function in patients with type 2 diabetes and hypertension, especially those with evidence of microalbuminuria or proteinuria. It helps to slow the progression of kidney disease, preserving renal function and reducing the risk of end-stage renal disease.
Side Effects of LOSARVAS-50 TAB
Like all medicines, LOSARVAS-50 TAB can cause side effects, although not everybody gets them. Most side effects are mild and temporary.
Common side effects
- Dizziness
- Fatigue
- Low blood pressure (hypotension)
- Mild increase in blood potassium levels (hyperkalemia)
- Headache
Serious side effects are rare but require immediate medical attention.
- Angioedema (swelling of the face, lips, throat)
- Severe hyperkalemia (high potassium levels)
- Severe kidney problems or acute renal failure
If you experience any persistent or severe side effects, or notice any other unusual symptoms, contact your doctor immediately. Do not stop taking the medication without consulting your healthcare provider.
How to use LOSARVAS-50 TAB
- Adults:
The usual starting dose for hypertension is 50 mg once daily. The dose may be increased to 100 mg once daily based on blood pressure response. For heart failure or diabetic nephropathy, the dosage will be determined by your doctor, often starting lower and gradually increasing.
- Children:
Losartan is generally not recommended for children under 6 years of age. For children aged 6 years and older, the dosage should be determined by a pediatrician based on body weight and specific condition, usually starting at a lower dose and carefully titrating.
- Elderly:
No initial dosage adjustment is generally required for elderly patients. However, caution should be exercised, and blood pressure should be monitored closely, especially in those with potential volume depletion or impaired renal function.
- Missed Dose:
If you miss a dose of LOSARVAS-50 TAB, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.
How LOSARVAS-50 TAB works
Losartan Potassium, the active ingredient in LOSARVAS-50 TAB, belongs to a class of drugs known as Angiotensin Receptor Blockers (ARBs). Its primary mechanism of action involves selectively blocking the binding of angiotensin II to the AT1 receptor, which is found in various tissues, including vascular smooth muscle and the adrenal glands. Angiotensin II is a potent vasoconstrictor and a key hormone in the Renin-Angiotensin-Aldosterone System (RAAS) that contributes to increased blood pressure and fluid retention. By blocking the AT1 receptor, Losartan prevents angiotensin II from exerting its effects, leading to vasodilation (widening of blood vessels), decreased aldosterone secretion, and reduced sympathetic nervous system activity. This results in a significant reduction in peripheral vascular resistance and, consequently, a lowering of blood pressure. The selective blockade also helps to protect target organs like the kidneys and heart from the damaging effects of chronic hypertension and high angiotensin II levels.
Precautions
- Inform your doctor if you are pregnant, planning to conceive, or breastfeeding.
- Exercise caution if you have kidney disease, especially renal artery stenosis, or liver impairment.
- Monitor potassium levels regularly, especially if you are taking potassium-sparing diuretics or potassium supplements.
- Avoid dehydration; drink plenty of fluids unless advised otherwise by your doctor.
- Inform your doctor about all other medications you are taking, including over-the-counter drugs and herbal supplements.
- Patients with a history of angioedema should use Losartan with extreme caution.
Safety Advice
Alcohol
CAUTIONConsuming alcohol while taking LOSARVAS-50 TAB may increase the blood pressure-lowering effect, leading to dizziness or lightheadedness. It is advisable to limit or avoid alcohol intake.
Pregnancy
UNSAFELOSARVAS-50 TAB is unsafe to use during pregnancy, especially in the second and third trimesters, as it can cause serious harm or death to the unborn baby. Consult your doctor immediately if you become pregnant while on this medication.
Breastfeeding
CONSULT YOUR DOCTORIt is not known whether Losartan passes into breast milk. Therefore, it is advisable to consult your doctor before taking LOSARVAS-50 TAB if you are breastfeeding. Your doctor will weigh the benefits against the potential risks.
Driving
CAUTIONLOSARVAS-50 TAB may cause dizziness or lightheadedness, especially when you first start taking it or when the dose is increased. Avoid driving or operating heavy machinery until you know how the medication affects you.
Kidney
CONSULT YOUR DOCTORLOSARVAS-50 TAB should be used with caution in patients with kidney disease. Your doctor may need to adjust the dosage and monitor your kidney function regularly. It is contraindicated in severe renal impairment.
Liver
CONSULT YOUR DOCTORPatients with liver impairment should use LOSARVAS-50 TAB with caution. Your doctor may prescribe a lower starting dose and monitor liver function tests regularly to ensure safety and efficacy.
Fact Box
Frequently asked questions by patients
Q: How long does it take for LOSARVAS-50 TAB to work?
A: You may start to see a reduction in your blood pressure within a few hours of taking the first dose. However, the full blood pressure-lowering effect typically develops over 3 to 6 weeks of consistent use. It's important to continue taking it regularly as prescribed.
Q: Can I stop taking LOSARVAS-50 TAB if my blood pressure is normal?
A: No, you should not stop taking LOSARVAS-50 TAB without consulting your doctor, even if your blood pressure appears normal. Hypertension is often a chronic condition, and stopping the medication abruptly can lead to a sudden increase in blood pressure, potentially causing serious health risks. Your doctor will guide you on the appropriate duration of treatment.
Q: Does LOSARVAS-50 TAB cause weight gain?
A: Weight gain is not a commonly reported side effect of Losartan Potassium. If you experience unexplained weight changes, it's advisable to discuss this with your doctor, as it might be related to other factors or underlying conditions.
Q: Is it safe to take LOSARVAS-50 TAB with other medications?
A: It is crucial to inform your doctor about all other medications, including over-the-counter drugs, herbal supplements, and vitamins, you are currently taking. Some medications, like NSAIDs, potassium supplements, or certain diuretics, can interact with Losartan. Your doctor can assess potential interactions and adjust your treatment plan accordingly.
Frequently Asked Questions
Q: What should I do if I experience dizziness after taking LOSARVAS-50 TAB?
Dizziness is a common side effect, especially when you first start the medication or when the dose is increased. If you feel dizzy, sit or lie down until the feeling passes. Avoid sudden movements. If dizziness is severe or persistent, inform your doctor, as a dosage adjustment might be necessary.
Q: Can LOSARVAS-50 TAB affect my kidney function?
While LOSARVAS-50 TAB can protect kidneys in diabetic patients, it can also affect kidney function in certain individuals, especially those with pre-existing kidney conditions or dehydration. Your doctor will monitor your kidney function regularly through blood tests to ensure it's safe for you.
Q: What lifestyle changes should I adopt while taking LOSARVAS-50 TAB?
Adopting a healthy lifestyle is crucial for managing high blood pressure. This includes following a low-salt, balanced diet, engaging in regular physical activity, maintaining a healthy weight, limiting alcohol intake, and quitting smoking. These changes can enhance the effectiveness of LOSARVAS-50 TAB.
Q: Are there any dietary restrictions while on LOSARVAS-50 TAB?
While there are no strict dietary restrictions, it's generally advised to limit foods high in potassium (like bananas, oranges, leafy greens) if your doctor has concerns about hyperkalemia. Also, reducing sodium intake is beneficial for blood pressure management. Always follow your doctor's specific dietary advice.
Q: What are the signs of an allergic reaction to LOSARVAS-50 TAB?
Signs of a severe allergic reaction (angioedema) include swelling of the face, lips, tongue, or throat, difficulty breathing or swallowing, and severe itching or rash. If you experience any of these symptoms, seek immediate medical attention as it can be life-threatening.
Additional Information
LOSARVAS-50 TAB (Losartan Potassium 50mg) is a vital medication for effectively managing high blood pressure, reducing the risk of cardiovascular events like stroke and heart attack, and supporting heart and kidney health. Its mechanism of action as an Angiotensin Receptor Blocker provides a targeted approach to blood pressure control, making it a cornerstone in the treatment of hypertension and related conditions. Consistent adherence to your doctor's prescribed dosage and regular monitoring of your blood pressure are crucial for achieving the best therapeutic outcomes. Remember that medication works best when combined with a healthy lifestyle, including a balanced diet, regular exercise, and avoiding harmful habits. Always communicate any concerns or side effects with your healthcare provider to ensure your treatment plan remains safe and effective. Your doctor is your best resource for personalized medical advice and care.
