PRODUCT INTRODUCTION

LOSARVAS-25 TAB, containing Losartan Potassium 25mg, is a widely prescribed medication in India for managing high blood pressure (hypertension). As an Angiotensin Receptor Blocker (ARB), it effectively relaxes blood vessels, allowing blood to flow more easily and reducing the workload on the heart. This medication is crucial in preventing serious cardiovascular events such as strokes, heart attacks, and kidney problems. It is also used to protect the kidneys in patients with type 2 diabetes and high blood pressure, helping to slow the progression of kidney disease. Always consult a healthcare professional for proper diagnosis and dosage to ensure optimal health outcomes.

Uses of LOSARVAS-25 TAB

LOSARVAS-25 TAB is primarily used to treat various cardiovascular conditions, helping to improve heart health and prevent complications.

  • Hypertension (High Blood Pressure)

    LOSARVAS-25 TAB is highly effective in lowering elevated blood pressure, reducing the risk of heart attacks, strokes, and kidney damage. It helps to relax blood vessels, making it easier for the heart to pump blood throughout the body, thus maintaining healthy blood pressure levels and promoting overall cardiovascular well-being.

  • Diabetic Nephropathy

    For patients with type 2 diabetes and high blood pressure, LOSARVAS-25 TAB helps to slow the progression of kidney disease. It protects the kidneys by reducing the pressure within the small blood vessels of the kidneys, thereby preserving kidney function and delaying the need for dialysis or kidney transplantation in affected individuals.

  • Heart Failure

    In certain cases of heart failure, LOSARVAS-25 TAB may be prescribed to improve symptoms and reduce the risk of hospitalization. It helps to decrease the workload on the heart by relaxing blood vessels and reducing fluid retention, allowing the heart to pump more efficiently and improving the patient's quality of life.

Side Effects of LOSARVAS-25 TAB

Like all medicines, LOSARVAS-25 TAB can cause side effects, although not everybody gets them. Most side effects are mild and temporary and may subside as your body adjusts to the medication.

Common side effects

  • Dizziness
  • Fatigue
  • Low blood pressure (hypotension)
  • Headache
  • Diarrhea

Less common or rare but potentially serious side effects include:

  • Angioedema (swelling of face, lips, throat)
  • Hyperkalemia (high potassium levels)
  • Kidney problems
  • Liver problems
  • Allergic reactions

If any of these side effects persist or worsen, or if you experience any other unusual symptoms, consult your doctor immediately. Do not stop taking the medication without medical advice, even if you feel unwell.

How to use LOSARVAS-25 TAB

  • Adults:

    The usual starting dose of LOSARVAS-25 TAB for hypertension is 50 mg once daily. The dose can be adjusted by your doctor based on blood pressure response, typically ranging from 25 mg to 100 mg once daily. For diabetic nephropathy, the usual starting dose is 50 mg once daily, titrated up to 100 mg once daily as needed. Take the tablet with or without food, at the same time each day.

  • Children:

    The safety and efficacy of Losartan Potassium in children under 6 years of age have not been established. For children aged 6 years and older with hypertension, the starting dose is usually 0.7 mg/kg once daily (up to a maximum of 50 mg). Dosage adjustments should be made under strict medical supervision by a pediatrician.

  • Elderly:

    No initial dosage adjustment is generally required for elderly patients with normal renal and hepatic function. However, a lower starting dose of 25 mg once daily may be considered for very elderly patients or those with potential volume depletion, as they may be more sensitive to the effects of the medication. Close monitoring is recommended by a healthcare professional.

  • Missed Dose:

    If you miss a dose of LOSARVAS-25 TAB, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one, as this can increase the risk of side effects. Consult your doctor if you frequently miss doses.

How LOSARVAS-25 TAB works

Losartan Potassium, the active ingredient in LOSARVAS-25 TAB, works by selectively blocking the binding of angiotensin II to the AT1 receptor, which is found in many tissues, including vascular smooth muscle and the adrenal gland. Angiotensin II is a potent vasoconstrictor and a primary hormone of the renin-angiotensin system, playing a significant role in the pathophysiology of hypertension and heart failure. By blocking these receptors, Losartan prevents angiotensin II from exerting its effects, leading to vasodilation (widening of blood vessels), decreased aldosterone secretion, and reduced sodium and water reabsorption. These actions collectively lower blood pressure and reduce the strain on the heart, thereby improving cardiovascular outcomes. Its selective action minimizes side effects often associated with ACE inhibitors, such as a dry cough.

Precautions

  • Avoid during pregnancy and breastfeeding due to potential harm to the fetus/infant.
  • Inform your doctor about any history of kidney disease or liver impairment.
  • Monitor potassium levels regularly, especially if you have kidney problems or are taking potassium-sparing diuretics.
  • Avoid potassium supplements or salt substitutes containing potassium without medical consultation.
  • May cause dizziness; avoid driving or operating heavy machinery until you know how it affects you.
  • Inform your doctor about all other medications you are taking, including OTC drugs, herbal supplements, and other blood pressure medicines.

Safety Advice

Alcohol

Alcohol

CAUTION

Consumption of alcohol while taking LOSARVAS-25 TAB may increase the blood pressure-lowering effect and can cause dizziness or lightheadedness. It is advisable to limit or avoid alcohol intake during treatment. Consult your doctor for personalized advice.

Pregnancy

Pregnancy

UNSAFE

LOSARVAS-25 TAB is not recommended during pregnancy, especially during the second and third trimesters, as it can cause serious harm or even death to the developing fetus. Women of childbearing potential should use effective contraception. Consult your doctor immediately if you become pregnant while on this medication.

Breastfeeding

Breastfeeding

CONSULT YOUR DOCTOR

It is not known whether Losartan Potassium passes into breast milk. Due to the potential for adverse effects on a nursing infant, breastfeeding is generally not recommended while taking LOSARVAS-25 TAB. Discuss the risks and benefits with your healthcare provider before initiating or continuing treatment.

Driving

Driving

CAUTION

LOSARVAS-25 TAB may cause dizziness or lightheadedness, especially when you first start taking it or when the dose is increased. If you experience these symptoms, avoid driving or operating heavy machinery until you know how the medication affects you. Be cautious when standing up from a sitting or lying position.

Kidney

Kidney

CAUTION

Patients with pre-existing kidney disease should use LOSARVAS-25 TAB with caution, as it may affect kidney function. Regular monitoring of kidney function tests (creatinine, BUN) and potassium levels is essential. Your doctor may adjust the dose based on your kidney health and individual response.

Liver

Liver

CAUTION

LOSARVAS-25 TAB should be used with caution in patients with liver impairment. The liver metabolizes Losartan, and impaired liver function can lead to increased levels of the drug in the body. Close monitoring and dose adjustments may be necessary. Consult your doctor if you have liver disease or experience any symptoms of liver dysfunction.

Fact Box

Chemical Class
Angiotensin II Receptor Blocker (ARB)
Habit Forming
No
Therapeutic Class
Antihypertensive
Action Class
Vasodilator, Blood Pressure Lowering Agent

Frequently asked questions by patients

Q: What should I do if my blood pressure remains high after taking LOSARVAS-25 TAB?

A: If your blood pressure does not respond adequately to LOSARVAS-25 TAB, do not increase the dose on your own. Consult your doctor, who may adjust your dosage, add another medication, or investigate other underlying causes. Consistent monitoring and adherence to the prescribed regimen are key for effective blood pressure control.

Q: Can I take LOSARVAS-25 TAB with other blood pressure medications?

A: LOSARVAS-25 TAB can often be taken with other antihypertensive medications, but this should only be done under the guidance of your doctor. Combining certain blood pressure medications requires careful monitoring to avoid excessive blood pressure drops or adverse interactions. Always inform your doctor about all medications you are taking.

Q: How long does it take for LOSARVAS-25 TAB to show its full effect?

A: While some blood pressure reduction may be seen within a few hours of the first dose, the full blood pressure-lowering effect of LOSARVAS-25 TAB typically develops over 3-6 weeks of consistent use. It is crucial to continue taking the medication as prescribed, even if you feel well, to achieve optimal control and long-term benefits.

Q: Is LOSARVAS-25 TAB safe for long-term use?

A: Yes, LOSARVAS-25 TAB is generally considered safe and effective for long-term management of hypertension and related conditions. Regular follow-ups with your doctor are important to monitor your blood pressure, kidney function, and potassium levels to ensure continued safety and efficacy over time. Do not discontinue without consulting your doctor.

Frequently Asked Questions

Q: What is LOSARVAS-25 TAB used for?

LOSARVAS-25 TAB is primarily used to treat high blood pressure (hypertension) and to protect the kidneys in patients with type 2 diabetes and high blood pressure. It helps prevent serious conditions like strokes, heart attacks, and kidney failure by relaxing blood vessels and improving blood flow throughout the body.

Q: How should I take LOSARVAS-25 TAB?

Take LOSARVAS-25 TAB exactly as prescribed by your doctor, usually once daily, with or without food. Try to take it at the same time each day to maintain consistent levels in your body. Do not crush, chew, or break the tablet; swallow it whole with water. Adhere strictly to your doctor's instructions.

Q: What are the common side effects of LOSARVAS-25 TAB?

Common side effects include dizziness, fatigue, headache, and low blood pressure. These are usually mild and temporary. If they persist or worsen, or if you experience any severe symptoms like swelling of the face or throat (angioedema), seek immediate medical attention from your healthcare provider.

Q: Can LOSARVAS-25 TAB affect my kidney function?

LOSARVAS-25 TAB can protect kidney function in patients with diabetic nephropathy. However, in some cases, especially in patients with pre-existing kidney issues or dehydration, it might affect kidney function. Your doctor will monitor your kidney health regularly while you are on this medication to ensure its safe use.

Q: What should I avoid while taking LOSARVAS-25 TAB?

Avoid potassium supplements or salt substitutes containing potassium without consulting your doctor, as this can lead to high potassium levels. Limit alcohol consumption. Do not take this medication if you are pregnant or breastfeeding without medical advice. Inform your doctor about all other medications you are taking to prevent interactions.

Additional Information

Category
Cardiovascular
FORM
TABLET
Tag
Angiotensin Receptor Blocker (ARB)
Packing
10x10
Composition
LOSARTAN POTASSIUM 25MG
Disclaimer: This information is provided for educational purposes only and should not replace professional medical advice. Always consult your healthcare provider before starting, stopping, or changing any medication. Individual results may vary. Keep this and all medications out of reach of children.

LOSARVAS-25 TAB, containing Losartan Potassium 25mg, is a vital medication for the effective management of hypertension and the prevention of its associated cardiovascular and renal complications. By acting as an Angiotensin Receptor Blocker, it offers a well-tolerated and potent solution for patients seeking to control their blood pressure and protect their vital organs. Its role in diabetic nephropathy underscores its importance in comprehensive patient care within the Indian healthcare landscape, contributing significantly to improved patient outcomes. Adherence to the prescribed dosage and regular medical follow-ups are crucial to maximize the therapeutic benefits and ensure patient safety. While generally safe, awareness of potential side effects and necessary precautions, especially regarding pregnancy and interactions with other medications, is paramount. Always consult your healthcare provider for personalized advice and to address any concerns regarding your treatment plan with LOSARVAS-25 TAB. This medication empowers patients to take an active role in managing their cardiovascular health effectively and responsibly.

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