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Neurological
LEVICETAM-750 TAB
SALT COMPOSITION
LEVETIRACETAM 750MGTYPE
TABLET
STORAGE
Store LEVICETAM-750 TAB below 25°C, in a cool, dry place. Protect from light and moisture. Keep out of reach of children and pets.
PRODUCT INTRODUCTION
LEVICETAM-750 TAB, containing Levetiracetam 750mg, is an advanced antiepileptic medication widely used in India for the management of various seizure disorders. It is prescribed for adults and children to control partial-onset seizures, myoclonic seizures in juvenile myoclonic epilepsy, and primary generalized tonic-clonic seizures. This medication helps to stabilize electrical activity in the brain, thereby reducing the frequency and severity of epileptic fits. As a crucial component of epilepsy treatment regimens, LEVICETAM-750 TAB offers patients a reliable option for improving their quality of life by providing effective seizure control.
Uses of LEVICETAM-750 TAB
LEVICETAM-750 TAB is primarily used to treat and prevent various types of epileptic seizures. It can be used alone or in combination with other antiepileptic medications.
- Partial-Onset Seizures
This medication is highly effective in treating partial-onset seizures, with or without secondary generalization, in adults and children aged 4 years and older. It helps to reduce the frequency and intensity of these seizures, which originate in a specific area of the brain.
- Myoclonic Seizures
LEVICETAM-750 TAB is indicated for the treatment of myoclonic seizures in adults and adolescents aged 12 years and older with juvenile myoclonic epilepsy. It helps to control the sudden, brief, shock-like jerks or twitches of a muscle or a group of muscles.
- Primary Generalized Tonic-Clonic Seizures
It is also prescribed for the treatment of primary generalized tonic-clonic seizures in adults and adolescents aged 12 years and older with idiopathic generalized epilepsy. This helps manage seizures that affect both sides of the brain from the outset, often involving loss of consciousness and convulsions.
Side Effects of LEVICETAM-750 TAB
Like all medications, LEVICETAM-750 TAB can cause side effects, although not everybody gets them. Most side effects are mild to moderate and temporary.
Common side effects
- Drowsiness
- Dizziness
- Fatigue
- Weakness
- Irritability
- Aggression
- Nausea
- Headache
- Infection
Less common but more serious side effects may occur. Seek immediate medical attention if you experience any of these:
- Suicidal thoughts or behavior
- Severe skin reactions (e.g., Stevens-Johnson syndrome)
- Blood dyscrasias (e.g., neutropenia, thrombocytopenia)
If any side effect bothers you or persists, please consult your doctor. Do not stop the medication without medical advice.
How to use LEVICETAM-750 TAB
- Adults:
The usual starting dose is 500 mg twice daily. The dose may be increased by 500 mg twice daily every 2 to 4 weeks, up to a maximum of 1500 mg twice daily, based on clinical response and tolerability. It can be taken with or without food.
- Children:
For children aged 4 years and older, dosing is typically weight-based. Initial dose is usually 10 mg/kg twice daily, increasing up to 30 mg/kg twice daily. Always follow the pediatrician's specific instructions and dose adjustments.
- Elderly:
No specific dose adjustment is required solely based on age. However, dose adjustments may be necessary for elderly patients with impaired renal function. Close monitoring of renal parameters is recommended.
- Missed Dose:
If you miss a dose of LEVICETAM-750 TAB, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.
How LEVICETAM-750 TAB works
Levetiracetam, the active ingredient in LEVICETAM-750 TAB, exerts its anticonvulsant effects through a unique mechanism of action distinct from other antiepileptic drugs. It selectively binds to the synaptic vesicle protein 2A (SV2A) found in the brain and spinal cord. While the precise mechanism by which SV2A binding contributes to antiepileptic activity is not fully understood, it is believed to modulate neurotransmitter release, particularly GABAergic and glutamatergic transmission, without directly affecting ion channels or benzodiazepine receptors. This modulation helps to normalize the hyperexcitability of neurons, which is characteristic of epileptic seizures. By stabilizing neuronal membranes and preventing excessive synchronized firing, Levetiracetam effectively reduces the propagation of seizure activity. Its novel mechanism minimizes interactions with other antiepileptic drugs, making it a valuable option for adjunctive therapy.
Precautions
- Patients with kidney problems may require a lower dose; consult your doctor for adjustment.
- Monitor for changes in mood or behavior, including suicidal thoughts, especially at the beginning of treatment or during dose changes.
- Avoid abrupt discontinuation of the medication, as it may increase seizure frequency. Taper off gradually under medical supervision.
- Use with caution in patients with a history of psychiatric disorders.
- May cause dizziness and drowsiness; avoid driving or operating heavy machinery until you know how it affects you.
- Inform your doctor about all other medications you are taking to avoid potential drug interactions.
Safety Advice
Alcohol
CAUTIONConsuming alcohol while taking LEVICETAM-750 TAB can increase the risk of central nervous system side effects such as dizziness, drowsiness, and impaired concentration. It is advisable to limit or avoid alcohol intake.
Pregnancy
CONSULT YOUR DOCTORLEVICETAM-750 TAB should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. It is crucial to discuss the risks and benefits with your doctor if you are pregnant or planning a pregnancy.
Breastfeeding
CONSULT YOUR DOCTORLevetiracetam is excreted into human breast milk. Therefore, breastfeeding is not recommended while taking LEVICETAM-750 TAB unless the potential benefits outweigh the potential risks to the infant. Consult your doctor for guidance.
Driving
UNSAFELEVICETAM-750 TAB can cause dizziness, drowsiness, and blurred vision, which may impair your ability to drive or operate machinery safely. It is advised to avoid driving or engaging in activities requiring mental alertness until you know how the medication affects you.
Kidney
CONSULT YOUR DOCTORDose adjustment of LEVICETAM-750 TAB is necessary for patients with impaired renal function, as the drug is primarily eliminated by the kidneys. Your doctor will assess your kidney function and adjust the dosage accordingly.
Liver
SAFE IF PRESCRIBEDLevetiracetam is minimally metabolized by the liver, so dose adjustment is generally not required in patients with mild to moderate hepatic impairment. However, caution is advised in severe hepatic impairment, and your doctor will monitor your condition.
Fact Box
Frequently asked questions by patients
Q: How quickly does LEVICETAM-750 TAB start working?
A: The effects of LEVICETAM-750 TAB can be noticed within a few days to weeks as the drug concentration builds up in your system. Full therapeutic benefits may take longer, and consistent use as prescribed is key for optimal seizure control.
Q: Can I stop taking LEVICETAM-750 TAB if I feel better?
A: No, you should never stop taking LEVICETAM-750 TAB abruptly, even if your seizures are well-controlled. Sudden discontinuation can lead to an increase in seizure frequency or severity. Always consult your doctor for a gradual tapering plan.
Q: Does LEVICETAM-750 TAB interact with other medications?
A: LEVICETAM-750 TAB has a relatively low potential for drug interactions compared to other antiepileptics. However, it's crucial to inform your doctor about all prescription, over-the-counter, and herbal supplements you are taking to avoid any unforeseen interactions.
Q: What if I experience mood changes while on this medication?
A: Mood changes, irritability, aggression, or even suicidal thoughts are rare but serious side effects. If you or your family notice any significant changes in mood or behavior, contact your doctor immediately for advice and evaluation.
Frequently Asked Questions
Q: Is LEVICETAM-750 TAB safe for long-term use?
Yes, LEVICETAM-750 TAB is generally considered safe for long-term use in managing epilepsy. Regular follow-ups with your doctor are important to monitor its effectiveness, potential side effects, and to make any necessary dose adjustments over time. Adherence to prescribed dosage and lifestyle recommendations is crucial for sustained seizure control.
Q: Can LEVICETAM-750 TAB affect my diet or specific foods?
Generally, LEVICETAM-750 TAB does not have specific dietary restrictions and can be taken with or without food. However, maintaining a balanced diet and avoiding excessive caffeine or stimulants may complement your epilepsy management. Always discuss any dietary concerns with your healthcare provider.
Q: What should I do in case of an overdose?
In case of an overdose of LEVICETAM-750 TAB, seek immediate medical attention or contact an emergency service. Symptoms of overdose may include severe drowsiness, agitation, aggression, decreased consciousness, respiratory depression, and coma. Prompt medical intervention is essential.
Q: How should I store LEVICETAM-750 TAB?
Store LEVICETAM-750 TAB at room temperature, ideally below 25°C, in a dry place away from direct light and moisture. Keep the tablets in their original packaging to protect them. Ensure the medication is kept out of reach and sight of children and pets to prevent accidental ingestion.
Q: Does LEVICETAM-750 TAB cause weight gain?
Weight changes are not commonly reported as a significant side effect of LEVICETAM-750 TAB. However, individual responses to medication can vary. If you notice any unexpected weight changes, it is advisable to discuss them with your doctor, who can evaluate if it's related to the medication or other factors.
Additional Information
LEVICETAM-750 TAB, with its active ingredient Levetiracetam 750mg, stands as a cornerstone in the effective management of various epileptic seizure types in India. Its unique mechanism of action, targeting the SV2A protein, offers a reliable and generally well-tolerated option for both monotherapy and adjunctive treatment. By helping to stabilize neuronal activity, it significantly contributes to reducing seizure frequency and improving the overall quality of life for patients. Adherence to the prescribed dosage and regular medical consultation are paramount for achieving optimal therapeutic outcomes and minimizing potential side effects. Patients are encouraged to maintain open communication with their healthcare providers regarding any concerns, side effects, or changes in their health status. LEVICETAM-750 TAB empowers individuals living with epilepsy to lead more stable and productive lives, underscoring its importance in neurological care.
