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Neurological
LEVICETAM-500MG TAB
SALT COMPOSITION
LEVETIRACETAM-500MGTYPE
TABLET
STORAGE
Store below 25°C in a dry place, protected from light and moisture. Keep out of reach of children.
PRODUCT INTRODUCTION
LEVICETAM-500MG TAB is a crucial medication designed to manage and control various types of epileptic seizures. Containing Levetiracetam 500mg, this tablet is widely prescribed by neurologists in India to help patients achieve better seizure control and improve their overall quality of life. It works by stabilizing electrical activity in the brain, thereby reducing the frequency and severity of seizures. LEVICETAM-500MG TAB is an essential part of epilepsy management, offering a reliable therapeutic option for both adults and children with epilepsy. Always consult your doctor for proper diagnosis and dosage.
Uses of LEVICETAM-500MG TAB
LEVICETAM-500MG TAB is primarily used in the treatment of epilepsy, a neurological disorder characterized by recurrent seizures. It is effective in managing various forms of seizures.
- Partial-Onset Seizures
This medication is indicated for the treatment of partial-onset seizures with or without secondary generalization in adults and children aged 4 years and older. It helps to reduce the frequency and intensity of these seizures, which originate in a specific area of the brain.
- Myoclonic Seizures
LEVICETAM-500MG TAB is also used as adjunctive therapy in the treatment of myoclonic seizures in adults and adolescents aged 12 years and older with juvenile myoclonic epilepsy. It helps to control the sudden, brief jerking or twitching movements characteristic of these seizures.
- Primary Generalized Tonic-Clonic Seizures
For adults and adolescents aged 6 years and older with primary generalized tonic-clonic seizures, LEVICETAM-500MG TAB can be prescribed as adjunctive therapy. These seizures affect both sides of the brain and involve loss of consciousness and muscle stiffening followed by jerking.
Side Effects of LEVICETAM-500MG TAB
Like all medicines, LEVICETAM-500MG TAB can cause side effects, although not everybody gets them. Most side effects are mild to moderate and often improve with continued use.
Common side effects
- Drowsiness or sleepiness
- Dizziness
- Weakness or fatigue
- Headache
- Nausea or vomiting
Less common or rare side effects can be more serious and may require medical attention. Contact your doctor immediately if you experience any of these:
- Mood changes or aggression
- Suicidal thoughts or behavior
- Severe skin reactions (e.g., rash, blistering)
- Unusual bleeding or bruising
If any side effect bothers you or does not go away, please consult your doctor. Do not stop taking the medication without consulting your healthcare provider.
How to use LEVICETAM-500MG TAB
- Adults:
The usual starting dose for adults is 500 mg twice daily. The dose may be increased by 500 mg twice daily every 2 weeks, up to a maximum of 1500 mg twice daily, based on individual response and tolerability. Always follow your doctor's instructions precisely.
- Children:
For children, dosing is typically weight-based and depends on the specific seizure type and age. It is crucial to consult a pediatrician for accurate dosage instructions. The medication is usually started at a lower dose and gradually increased.
- Elderly:
Elderly patients may require a lower starting dose and slower titration due to potential age-related decreases in kidney function. Close monitoring for side effects is recommended. Dosage adjustments should always be made under medical supervision.
- Missed Dose:
If you miss a dose of LEVICETAM-500MG TAB, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.
How LEVICETAM-500MG TAB works
Levetiracetam, the active ingredient in LEVICETAM-500MG TAB, exerts its anticonvulsant effects through a unique mechanism that differs from other antiepileptic drugs. Its primary mode of action involves binding to the synaptic vesicle protein 2A (SV2A) in the brain. This binding is believed to modulate neurotransmitter release, specifically by inhibiting the release of excitatory neurotransmitters and promoting the release of inhibitory ones. This action helps to normalize the hyperexcitable neuronal activity characteristic of epileptic seizures. By selectively targeting SV2A, Levetiracetam helps to prevent the excessive electrical discharges that lead to seizures without directly affecting ion channels or neurotransmitter receptors in a broad manner. This distinct mechanism contributes to its efficacy across a broad spectrum of seizure types and its relatively favorable side effect profile compared to some older antiepileptic medications. It helps to restore the balance of electrical activity in the brain, thereby reducing the likelihood of seizure occurrence.
Precautions
- Do not stop taking LEVICETAM-500MG TAB suddenly, as this may increase seizure frequency.
- Inform your doctor if you have kidney disease, as dose adjustment may be necessary.
- Monitor for any changes in mood or behavior, including thoughts of self-harm.
- Avoid driving or operating heavy machinery until you know how the medicine affects you.
- Inform your doctor about all other medications you are taking, including herbal supplements.
- Use with caution in patients with a history of psychiatric disorders.
Safety Advice
Alcohol
CAUTIONConsuming alcohol while taking LEVICETAM-500MG TAB may increase side effects such as dizziness, drowsiness, and difficulty concentrating. It is advisable to limit or avoid alcohol intake.
Pregnancy
CONSULT YOUR DOCTORLEVICETAM-500MG TAB should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. It is crucial to discuss the risks and benefits with your doctor if you are pregnant or planning a pregnancy.
Breastfeeding
CONSULT YOUR DOCTORLevetiracetam is known to pass into breast milk. Therefore, breastfeeding while taking LEVICETAM-500MG TAB is generally not recommended. Discuss the best feeding option with your healthcare provider.
Driving
UNSAFELEVICETAM-500MG TAB can cause dizziness, drowsiness, and blurred vision, which may impair your ability to drive or operate machinery safely. It is advised to avoid such activities until you are certain how the medication affects you.
Kidney
CAUTIONPatients with kidney disease should use LEVICETAM-500MG TAB with caution. Dose adjustments may be necessary based on renal function. Regular monitoring of kidney parameters may be advised by your doctor.
Liver
CONSULT YOUR DOCTORWhile LEVICETAM-500MG TAB is primarily metabolized by the kidneys, caution is advised in patients with severe liver impairment. Consult your doctor for appropriate guidance and monitoring if you have liver issues.
Fact Box
Frequently asked questions by patients
Q: Can LEVICETAM-500MG TAB be stopped suddenly?
A: No, it is crucial not to stop taking LEVICETAM-500MG TAB suddenly without consulting your doctor. Abrupt discontinuation can lead to an increase in seizure frequency or severity. Your doctor will guide you on how to gradually reduce the dose if needed.
Q: How long do I need to take LEVICETAM-500MG TAB?
A: The duration of treatment with LEVICETAM-500MG TAB varies depending on your condition, response to treatment, and your doctor's assessment. Epilepsy is often a long-term condition, and medication may be required for an extended period. Follow your doctor's advice.
Q: Does LEVICETAM-500MG TAB cause weight gain?
A: Weight changes are not commonly reported as a significant side effect of Levetiracetam. Some patients may experience minor fluctuations, but it is generally considered weight-neutral compared to some other antiepileptic drugs. Discuss any concerns with your doctor.
Q: What if I experience mood changes while on this medication?
A: Levetiracetam can sometimes cause mood changes, irritability, or even suicidal thoughts. It is important to inform your doctor immediately if you notice any significant changes in your mood, behavior, or thoughts. They can assess the situation and adjust your treatment plan if necessary.
Frequently Asked Questions
Q: Is LEVICETAM-500MG TAB safe for children?
Yes, LEVICETAM-500MG TAB is approved for use in children for certain types of seizures, typically from 4 years of age for partial-onset seizures and 6 or 12 years for other seizure types, depending on the specific indication. The dosage for children is carefully determined by a pediatrician based on their weight and condition. Always ensure strict adherence to the prescribed pediatric dosage.
Q: Can LEVICETAM-500MG TAB interact with other medicines?
Levetiracetam has a relatively low potential for drug interactions compared to many other antiepileptic drugs. However, it's essential to inform your doctor about all medications, including over-the-counter drugs, herbal supplements, and vitamins, to avoid any potential interactions. Your doctor can review your complete medication list to ensure safety.
Q: What should I do if I forget to take a dose?
If you miss a dose of LEVICETAM-500MG TAB, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a forgotten one, as this can increase the risk of side effects. Consistency is key in epilepsy management.
Q: Does LEVICETAM-500MG TAB require regular blood tests?
Unlike some other antiepileptic drugs, Levetiracetam generally does not require routine therapeutic drug monitoring (blood tests to check drug levels) because its efficacy is not directly correlated with plasma concentrations in the same way. However, your doctor may order blood tests to monitor kidney function, especially if you have pre-existing kidney conditions, as the drug is primarily excreted through the kidneys.
Q: Can I consume grapefruit juice while taking this medication?
There are no known significant interactions between grapefruit juice and Levetiracetam. Unlike some other medications that are metabolized by specific liver enzymes that grapefruit can inhibit, Levetiracetam's metabolism is different. Therefore, consuming grapefruit juice is generally considered safe with LEVICETAM-500MG TAB. Always consult your doctor if you have specific dietary concerns.
Additional Information
LEVICETAM-500MG TAB, containing Levetiracetam, stands as a vital antiepileptic medication offering effective control over various seizure types, including partial-onset, myoclonic, and primary generalized tonic-clonic seizures. Its unique mechanism of action, involving the modulation of neurotransmitter release, contributes to its efficacy and generally favorable tolerability profile. This medication plays a crucial role in improving the quality of life for individuals living with epilepsy by reducing seizure frequency and severity. Adherence to the prescribed dosage and administration schedule is paramount for optimal therapeutic outcomes. Patients are encouraged to maintain open communication with their healthcare providers regarding any side effects, concerns, or potential interactions with other medications. Regular follow-ups ensure that the treatment plan remains tailored to individual needs, promoting long-term seizure management and overall well-being. Always prioritize professional medical advice for your health journey.
