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Antifungals
ITRACORN 200 MG CAP
SALT COMPOSITION
ITRACONAZOLE 200MGTYPE
CAPSULE
STORAGE
Store ITRACORN 200 MG CAP below 25°C in a cool, dry place, protected from light and moisture. Keep out of reach of children and pets. Do not use after the expiry date printed on the packaging.
PRODUCT INTRODUCTION
ITRACORN 200 MG CAP is a potent antifungal medication widely used in India to treat a variety of fungal infections affecting different parts of the body. Containing Itraconazole 200mg, a triazole antifungal, it effectively combats systemic and superficial fungal diseases. This medication is crucial for managing conditions like candidiasis, aspergillosis, and dermatophytoses, offering relief and promoting recovery. Its broad-spectrum activity makes it a preferred choice for dermatologists and general physicians alike. Always consult a healthcare professional for proper diagnosis and treatment.
Uses of ITRACORN 200 MG CAP
ITRACORN 200 MG CAP is prescribed for the treatment of various fungal infections, both superficial and systemic.
- Onychomycosis (Fungal Nail Infections)
Itraconazole is highly effective in treating fungal infections of the fingernails and toenails. It works by eradicating the fungus embedded within the nail plate and nail bed, promoting the growth of healthy, clear nails over time. Treatment duration varies depending on the severity and location of the infection, often requiring several weeks to months for complete clearance.
- Systemic Fungal Infections
This medication is used to treat serious systemic fungal infections such as aspergillosis, blastomycosis, and histoplasmosis, which can affect the lungs, blood, and other organs. Itraconazole helps to control the spread of these infections throughout the body, reducing symptoms and preventing life-threatening complications. Close medical supervision is essential during treatment.
- Candidiasis (Yeast Infections)
ITRACORN 200 MG CAP is effective against various forms of candidiasis, including oral thrush (oropharyngeal candidiasis), esophageal candidiasis, and vulvovaginal candidiasis. It targets the Candida species responsible for these infections, providing symptomatic relief and preventing recurrence. It's also used in immunocompromised patients to prevent candidal infections.
Side Effects of ITRACORN 200 MG CAP
Like all medicines, ITRACORN 200 MG CAP can cause side effects, although not everybody gets them. Most side effects are mild to moderate and temporary.
Common side effects
- Nausea
- Abdominal pain
- Diarrhea
- Headache
- Dizziness
Less common but potentially serious side effects include:
- Liver problems (yellowing of skin/eyes, dark urine)
- Heart failure symptoms (shortness of breath, swelling)
- Allergic reactions (rash, itching, swelling)
If any side effect persists or worsens, or if you experience any severe symptoms, seek immediate medical attention. Do not discontinue the medication without consulting your doctor.
How to use ITRACORN 200 MG CAP
- Adults:
Dosage varies based on the type and severity of fungal infection. For Onychomycosis, a common regimen is 200 mg once daily for 3 months, or pulse therapy (200 mg twice daily for 1 week, followed by 3 weeks off, repeated for 2-3 cycles). For systemic infections, doses may range from 100-400 mg daily, often divided into two doses. Always take with a full meal for optimal absorption. Follow your doctor's instructions precisely.
- Children:
The use of Itraconazole in pediatric patients should be carefully considered and is generally not recommended unless the potential benefits outweigh the risks, especially for severe or life-threatening infections. Dosage will be determined by a specialist based on weight and the specific infection. Close monitoring for side effects is crucial.
- Elderly:
No specific dose adjustment is generally required for elderly patients, but caution is advised due to potential age-related decrease in renal or hepatic function. Monitoring of liver function tests may be more frequent. Always consult a doctor, as individual health conditions may necessitate dosage modifications.
- Missed Dose:
If you miss a dose of ITRACORN 200 MG CAP, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one, as this can increase the risk of side effects. Consult your doctor if you are unsure.
How ITRACORN 200 MG CAP works
Itraconazole, the active ingredient in ITRACORN 200 MG CAP, exerts its antifungal action by inhibiting the fungal cytochrome P450-dependent enzyme lanosterol 14-alpha-demethylase. This enzyme is vital for the biosynthesis of ergosterol, a key component of the fungal cell membrane. By blocking ergosterol synthesis, Itraconazole disrupts the integrity and permeability of the fungal cell membrane, leading to leakage of cellular contents and ultimately, fungal cell death. This fungistatic to fungicidal action effectively stops the growth and spread of various fungal pathogens. The selective inhibition ensures minimal impact on human cells, which primarily use cholesterol instead of ergosterol for their cell membranes. This targeted mechanism makes ITRACORN 200 MG CAP a highly effective treatment against a wide range of fungal infections.
Precautions
- Inform your doctor about all your medical conditions, especially liver or heart problems, before starting treatment.
- Avoid taking antacids, H2-blockers, or proton pump inhibitors within 2 hours of taking Itraconazole capsules, as they can reduce absorption.
- Regular monitoring of liver function tests is recommended during prolonged treatment.
- Report any symptoms of heart failure (e.g., shortness of breath, swelling of ankles) to your doctor immediately.
- Itraconazole interacts with many other medications; inform your doctor about all prescription and non-prescription drugs you are taking.
- Do not crush or chew the capsules; swallow them whole with a full meal.
Safety Advice
Alcohol
CAUTIONIt is advisable to limit or avoid alcohol consumption while taking ITRACORN 200 MG CAP. Alcohol can increase the risk of liver side effects, which is a known concern with Itraconazole. Consult your doctor for personalized advice.
Pregnancy
UNSAFEITRACORN 200 MG CAP is generally not recommended during pregnancy due to potential risks to the developing fetus. It should only be used if the potential benefits justify the potential risk to the fetus, as determined by a specialist. Always consult your doctor before taking this medicine if you are pregnant or planning a pregnancy.
Breastfeeding
UNSAFEItraconazole is excreted into breast milk and may cause harm to a nursing infant. Therefore, breastfeeding is not recommended while taking ITRACORN 200 MG CAP. Discuss the risks and benefits with your doctor to make an informed decision.
Driving
CAUTIONITRACORN 200 MG CAP may cause dizziness or visual disturbances in some individuals. If you experience these side effects, avoid driving or operating heavy machinery. It is important to know how you react to the medication before engaging in activities that require alertness.
Kidney
CAUTIONPatients with kidney disease should use ITRACORN 200 MG CAP with caution. Dose adjustments may be necessary based on the severity of renal impairment. Your doctor will assess your kidney function and determine the appropriate dosage to prevent accumulation and potential side effects.
Liver
CAUTIONITRACORN 200 MG CAP should be used with extreme caution in patients with pre-existing liver disease. Itraconazole can cause liver damage, and regular monitoring of liver function tests is essential during treatment. Report any signs of liver problems to your doctor immediately.
Fact Box
Frequently asked questions by patients
Q: Can I stop taking ITRACORN 200 MG CAP once my symptoms improve?
A: No, it is crucial to complete the full course of ITRACORN 200 MG CAP as prescribed by your doctor, even if your symptoms improve. Stopping early can lead to a recurrence of the infection and may make it harder to treat in the future. Always follow your doctor's instructions.
Q: What should I do if I experience severe stomach pain after taking this medicine?
A: Severe stomach pain, especially if accompanied by nausea, vomiting, or yellowing of the skin/eyes, could indicate a serious side effect like liver problems. You should seek immediate medical attention and inform your doctor about these symptoms without delay.
Q: Is ITRACORN 200 MG CAP effective against all types of fungal infections?
A: ITRACORN 200 MG CAP is effective against a broad spectrum of fungal infections caused by susceptible fungi, including yeasts and dermatophytes. However, it may not be effective against all fungal species. Your doctor will determine if this medication is appropriate for your specific infection based on diagnosis.
Q: Can I take ITRACORN 200 MG CAP with other medications?
A: Itraconazole interacts with numerous medications, including certain antacids, heart medications, cholesterol-lowering drugs, and sedatives. These interactions can alter the effectiveness of either drug or increase the risk of side effects. Always inform your doctor about all medications, supplements, and herbal products you are currently taking to avoid potential interactions.
Frequently Asked Questions
Q: How long does it take for ITRACORN 200 MG CAP to show results?
The time it takes for ITRACORN 200 MG CAP to show results varies depending on the type and severity of the fungal infection. For superficial infections like ringworm, improvement might be seen within a few weeks. For nail infections (onychomycosis) or systemic infections, it can take several months to see significant improvement, as the medication needs time to eradicate the fungus and allow healthy tissue to grow. Consistency in taking the medication as prescribed is key for effective results.
Q: Can ITRACORN 200 MG CAP be taken on an empty stomach?
No, ITRACORN 200 MG CAP should always be taken immediately after a full meal. Taking it with food significantly increases its absorption into the bloodstream, making it more effective. Taking it on an empty stomach can lead to reduced absorption and diminished efficacy. Always follow this instruction for optimal treatment outcomes.
Q: What are the signs of liver problems I should watch out for while taking this medicine?
While taking ITRACORN 200 MG CAP, it's important to be aware of potential signs of liver problems. These include unusual tiredness, severe stomach pain, dark urine, pale stools, yellowing of the skin or eyes (jaundice), and persistent nausea or vomiting. If you experience any of these symptoms, contact your doctor immediately, as prompt medical attention is crucial.
Q: Is ITRACORN 200 MG CAP safe for long-term use?
ITRACORN 200 MG CAP can be prescribed for long-term use, especially for chronic or severe fungal infections. However, prolonged use requires careful medical supervision, including regular monitoring of liver function tests and other relevant parameters, to detect and manage any potential side effects. Your doctor will assess the benefits versus risks for extended treatment durations.
Q: What if I accidentally take more than the prescribed dose?
If you accidentally take more than the prescribed dose of ITRACORN 200 MG CAP, seek immediate medical attention. Overdosing can increase the risk and severity of side effects, including potential liver toxicity or cardiac issues. Bring the medication packaging with you to the hospital or clinic to provide complete information to the healthcare professionals.
Additional Information
ITRACORN 200 MG CAP, containing Itraconazole 200mg, stands as a vital antifungal treatment in the Indian pharmaceutical landscape. Its efficacy against a wide array of fungal infections, from superficial skin and nail conditions to more serious systemic diseases, makes it a cornerstone in antifungal therapy. By inhibiting ergosterol synthesis, it effectively disrupts fungal cell membranes, leading to their eradication and promoting patient recovery. The importance of adhering to prescribed dosages and completing the full course of treatment cannot be overstated to ensure complete eradication of the infection and prevent recurrence. Patients are encouraged to take the capsule with a full meal to maximize absorption and therapeutic effect. While generally well-tolerated, awareness of potential side effects, especially those related to liver function, is crucial. Regular communication with a healthcare provider about any pre-existing conditions or concurrent medications is essential to ensure safe and effective use. ITRACORN 200 MG CAP offers a reliable solution for managing fungal infections, contributing significantly to public health by combating these often persistent and challenging conditions.