GABANEC-100 TAB

Uses of GABANEC-100 TAB

GABANEC-100 TAB is prescribed for various conditions involving nerve pain and seizure management. Below are its primary therapeutic uses:

• Neuropathic Pain

  GABANEC-100 TAB is highly effective in treating various forms of neuropathic pain, including post-herpetic neuralgia (nerve pain following shingles) and peripheral neuropathies, such as diabetic neuropathy. It works by modulating nerve activity, thereby reducing burning, shooting, or tingling sensations associated with nerve damage. Regular use as prescribed helps improve quality of life for individuals suffering from chronic nerve pain.

• Partial Seizures

  As an adjunctive therapy, GABANEC-100 TAB is used to control partial seizures (also known as focal seizures) in adults and children aged 3 years and older. It helps to stabilize electrical activity in the brain, reducing the frequency and severity of seizures. It is typically used in combination with other anti-epileptic medications when monotherapy is insufficient to achieve adequate seizure control.

• Restless Legs Syndrome (RLS)

  GABANEC-100 TAB is also indicated for the symptomatic treatment of moderate to severe primary Restless Legs Syndrome (RLS) in adults. RLS is a neurological disorder characterized by an irresistible urge to move the legs, often accompanied by uncomfortable sensations. Gabapentin helps to alleviate these symptoms, particularly those that occur at night, leading to improved sleep quality.

Side Effects of GABANEC-100 TAB

Like all medicines, GABANEC-100 TAB can cause side effects, although not everybody gets them. Most side effects are mild to moderate and often diminish with continued use as your body adjusts to the medication.

While less common, some serious side effects can occur. Seek immediate medical attention if you experience any of the following:

If any side effect bothers you or persists, please consult your doctor. Do not stop the medication abruptly without medical advice, as this can lead to withdrawal symptoms or worsening of your condition.

How to use GABANEC-100 TAB

• Adults:

  For neuropathic pain, the starting dose is typically 300mg once daily on day 1, 300mg twice daily on day 2, and 300mg three times daily on day 3. The dose can be gradually increased up to a maximum of 3600mg/day in three divided doses, based on individual response and tolerability. For partial seizures, the usual effective dose is 900mg to 3600mg per day in three divided doses. For RLS, the dose is usually 300mg once daily at bedtime, increasing to 1800mg/day if needed.

• Children:

  For partial seizures, in children aged 3-12 years, the starting dose is 10-15 mg/kg/day in three divided doses, titrated up to an effective dose of 25-35 mg/kg/day. For children 12 years and older, adult dosing guidelines apply. Dosage adjustments may be necessary based on weight, age, and renal function. Always follow the pediatrician's specific instructions.

• Elderly:

  Elderly patients may require lower doses due to potential age-related decline in renal function. Starting doses should be conservative, and titration should be slow to minimize side effects. Close monitoring for adverse reactions such as dizziness and somnolence is recommended. Renal function should be assessed before initiating treatment and monitored regularly.

• Missed Dose:

  If you miss a dose of GABANEC-100 TAB, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up. If you frequently miss doses, consult your doctor or pharmacist for advice.

How GABANEC-100 TAB works

Gabapentin, the active ingredient in GABANEC-100 TAB, is structurally related to the neurotransmitter gamma-aminobutyric acid (GABA), but its mechanism of action differs from that of other GABAergic agents. It is believed to exert its effects primarily by binding with high affinity to the alpha-2-delta subunit of voltage-gated calcium channels located in the central nervous system. This binding modulates the release of several excitatory neurotransmitters, including glutamate, noradrenaline, and substance P, which are implicated in pain transmission and seizure activity. By reducing the release of these neurotransmitters, Gabapentin helps to stabilize neuronal membranes and decrease neuronal excitability. This action contributes to its effectiveness in alleviating neuropathic pain by dampening abnormal nerve signals and in controlling partial seizures by preventing excessive electrical activity in the brain. It does not directly bind to GABA receptors, nor does it inhibit GABA reuptake or degradation.

Precautions

• Patients with kidney disease may require a dose adjustment; consult your doctor.
• Monitor for changes in mood or behavior, including suicidal thoughts, especially at the beginning of treatment or after dose changes.
• Avoid abrupt discontinuation of GABANEC-100 TAB, as it can lead to withdrawal symptoms or increased seizure frequency.
• May cause dizziness and drowsiness; avoid driving or operating heavy machinery until you know how it affects you.
• Use with caution in elderly patients due to increased risk of side effects like dizziness and falls.
• Inform your doctor about all other medications you are taking to avoid potential drug interactions.

Safety Advice

Alcohol

UNSAFE

Consumption of alcohol with GABANEC-100 TAB is unsafe. It can significantly increase drowsiness, dizziness, and impair your judgment and coordination. Avoid alcohol entirely during your treatment.

Pregnancy

CONSULT YOUR DOCTOR

GABANEC-100 TAB should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Limited data suggest potential risks. Always consult your doctor to weigh the benefits and risks before taking this medication if you are pregnant or planning pregnancy.

Breastfeeding

CONSULT YOUR DOCTOR

Gabapentin passes into breast milk in small amounts. While generally considered low risk, consult your doctor before breastfeeding. Your doctor will assess the potential risks to the infant versus the benefits of treatment for the mother.

Driving

UNSAFE

GABANEC-100 TAB can cause dizziness, drowsiness, and impaired concentration. It is unsafe to drive or operate heavy machinery until you are certain how this medication affects your ability to perform such tasks safely.

Kidney

CAUTION

GABANEC-100 TAB is primarily eliminated by the kidneys. Patients with kidney disease or impaired renal function require careful dose adjustments. Consult your doctor for appropriate dosing based on your kidney function tests.

Liver

SAFE IF PRESCRIBED

GABANEC-100 TAB is generally considered safe for use in patients with liver disease, as it is not significantly metabolized by the liver. However, always inform your doctor about any pre-existing liver conditions, and follow their advice.

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Frequently asked questions by patients

Frequently Asked Questions

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