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Antibiotics
ANOXINCLAV 375 TAB
SALT COMPOSITION
AMOXICILLIN 200MG + CLAVULANIC ACID 175MGTYPE
TABLET
STORAGE
Store below 25°C in a cool, dry place, protected from direct sunlight and moisture. Keep out of reach of children.
PRODUCT INTRODUCTION
ANOXINCLAV 375 TAB is a potent antibiotic medication widely used in India to combat various bacterial infections. This combination medicine contains Amoxicillin 200mg and Clavulanic Acid 175mg, working synergistically to provide a broad spectrum of antibacterial activity. It is prescribed by doctors for conditions affecting the respiratory tract, urinary tract, skin, and other parts of the body. ANOXINCLAV 375 TAB helps in effectively treating infections that might be resistant to amoxicillin alone, ensuring a faster recovery and improved patient outcomes. Always use this medication under medical supervision to ensure proper dosage and duration of treatment.
Uses of ANOXINCLAV 375 TAB
ANOXINCLAV 375 TAB is a versatile antibiotic combination indicated for the treatment of various bacterial infections.
- Respiratory Tract Infections
Effective in treating bacterial infections of the lungs and airways such as bronchitis, pneumonia, and sinusitis. It targets bacteria commonly responsible for these conditions, helping to clear infection and relieve symptoms like cough and difficulty breathing.
- Urinary Tract Infections (UTIs)
Prescribed for UTIs caused by susceptible bacteria. It helps eliminate bacteria from the bladder and kidneys, reducing symptoms like painful urination, frequent urges, and abdominal discomfort, leading to a quick recovery.
- Skin and Soft Tissue Infections
Used for various skin infections including cellulitis, wound infections, and abscesses. The combination effectively penetrates infected tissues, combating the bacteria responsible for inflammation, redness, and pus formation, promoting healing.
Side Effects of ANOXINCLAV 375 TAB
Like all medicines, ANOXINCLAV 375 TAB can cause side effects, although not everybody gets them. Most side effects are mild and temporary.
Common side effects
- Diarrhea
- Nausea
- Vomiting
- Skin rash
- Headache
- Abdominal pain
Less commonly, some individuals may experience more serious side effects that require immediate medical attention.
- Allergic reactions (hives, swelling, difficulty breathing)
- Liver problems (jaundice, dark urine)
- Clostridium difficile-associated diarrhea (severe, persistent diarrhea)
- Seizures
If you experience any severe or persistent side effects, or any signs of an allergic reaction, stop taking the medicine and consult your doctor immediately.
How to use ANOXINCLAV 375 TAB
- Adults:
The typical adult dosage is one ANOXINCLAV 375 TAB (Amoxicillin 200mg + Clavulanic Acid 175mg) taken orally every 8-12 hours, or as directed by a physician. It should be taken with food to minimize gastrointestinal upset. The exact duration of treatment depends on the severity and type of infection.
- Children:
Pediatric dosing should be determined by a doctor based on the child's weight, age, and the severity of the infection. It is crucial to follow the pediatrician's instructions precisely. For younger children, a suspension form might be more appropriate.
- Elderly:
Elderly patients may require dose adjustments, especially if they have impaired kidney function. A doctor will assess kidney function and prescribe the appropriate dosage to prevent accumulation and potential side effects. Close monitoring is recommended.
- Missed Dose:
If a dose is missed, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.
How ANOXINCLAV 375 TAB works
Amoxicillin is a penicillin-type antibiotic that works by inhibiting the synthesis of bacterial cell walls. It binds to penicillin-binding proteins (PBPs) located inside the bacterial cell wall, which are essential for the synthesis of peptidoglycan, a key component of the bacterial cell wall. This binding prevents the cross-linking of peptidoglycan units, leading to a weakened cell wall and ultimately causing the bacterial cell to lyse and die. However, many bacteria have developed resistance to amoxicillin by producing an enzyme called beta-lactamase, which inactivates amoxicillin. This is where Clavulanic Acid plays a crucial role. Clavulanic Acid is a beta-lactamase inhibitor that irreversibly binds to and inactivates beta-lactamase enzymes. By protecting amoxicillin from degradation, Clavulanic Acid extends the antibacterial spectrum of amoxicillin, making ANOXINCLAV 375 TAB effective against a broader range of bacteria, including those that produce beta-lactamase.
Precautions
- Inform your doctor if you have a history of allergic reactions to penicillin or other antibiotics.
- Use with caution in patients with liver disease or kidney impairment; dose adjustment may be necessary.
- Prolonged use of this antibiotic may lead to the growth of non-susceptible organisms, including fungi.
- Patients with mononucleosis should avoid this medication as it may cause a skin rash.
- It may interfere with certain laboratory tests, such as urine glucose tests.
- Complete the full course of treatment as prescribed, even if you feel better, to prevent recurrence and antibiotic resistance.
Safety Advice
Alcohol
CAUTIONAlcohol consumption during treatment with ANOXINCLAV 375 TAB is generally not recommended. While it may not directly interact with the antibiotic, it can exacerbate side effects like nausea or dizziness and may hinder your body's ability to fight the infection.
Pregnancy
CONSULT YOUR DOCTORANOXINCLAV 375 TAB should be used during pregnancy only if clearly needed and prescribed by a doctor. Animal studies have not shown harm, but human data is limited. Your doctor will weigh the benefits against potential risks.
Breastfeeding
CONSULT YOUR DOCTORAmoxicillin and Clavulanic Acid can pass into breast milk in small amounts. While generally considered safe, it can cause diarrhea or thrush in the infant. Consult your doctor to discuss the risks and benefits.
Driving
SAFEANOXINCLAV 375 TAB typically does not impair your ability to drive or operate machinery. However, if you experience side effects like dizziness or headache, avoid driving until you feel well.
Kidney
CAUTIONPatients with kidney disease should use ANOXINCLAV 375 TAB with caution. Dose adjustments may be necessary based on the severity of renal impairment. Regular monitoring of kidney function is advised by your doctor.
Liver
CAUTIONPatients with a history of liver problems should use this medication with caution. Although rare, liver injury can occur. Your doctor may recommend liver function tests during treatment.
Fact Box
Frequently asked questions by patients
Q: Can ANOXINCLAV 375 TAB be taken on an empty stomach?
A: It is generally recommended to take ANOXINCLAV 375 TAB with food to reduce the chances of stomach upset and improve absorption. Follow your doctor's specific instructions regarding meal timing.
Q: How long does it take for ANOXINCLAV 375 TAB to show effect?
A: You might start feeling better within a few days of starting ANOXINCLAV 375 TAB. However, it is crucial to complete the entire prescribed course of medication to ensure the infection is fully cleared and to prevent antibiotic resistance.
Q: Is ANOXINCLAV 375 TAB effective against viral infections?
A: No, ANOXINCLAV 375 TAB is an antibiotic and is only effective against bacterial infections. It will not work for viral infections like the common cold or flu. Using antibiotics for viral infections can lead to antibiotic resistance.
Q: What should I do if I experience severe diarrhea after taking this medicine?
A: If you experience severe or persistent diarrhea, especially if it's watery or bloody, while taking or after taking ANOXINCLAV 375 TAB, contact your doctor immediately. This could be a sign of a more serious condition called Clostridium difficile-associated diarrhea.
Frequently Asked Questions
Q: What is ANOXINCLAV 375 TAB used for?
ANOXINCLAV 375 TAB is an antibiotic used to treat a wide range of bacterial infections. These include infections of the respiratory tract (like bronchitis, pneumonia), urinary tract, skin and soft tissues, and ear, nose, and throat infections. It combines Amoxicillin with Clavulanic Acid to overcome bacterial resistance.
Q: How should I take ANOXINCLAV 375 TAB?
Take ANOXINCLAV 375 TAB exactly as prescribed by your doctor. It is usually taken orally, with food, every 8 or 12 hours. Do not crush or chew the tablet; swallow it whole with a glass of water. Always complete the full course of treatment, even if your symptoms improve.
Q: What are the common side effects of ANOXINCLAV 375 TAB?
Common side effects include nausea, vomiting, diarrhea, and skin rash. These are usually mild and temporary. If any of these side effects persist or worsen, or if you experience any severe reactions like an allergic rash, swelling, or difficulty breathing, seek immediate medical attention.
Q: Can I stop taking ANOXINCLAV 375 TAB if I feel better?
No, you should not stop taking ANOXINCLAV 375 TAB even if your symptoms improve and you start feeling better. Completing the full course of antibiotics is crucial to ensure all bacteria are eliminated and to prevent the infection from returning or developing antibiotic resistance.
Q: What if I am allergic to penicillin?
If you have a known allergy to penicillin or any other beta-lactam antibiotics, you must inform your doctor before starting ANOXINCLAV 375 TAB. This medication contains amoxicillin, which is a penicillin-type antibiotic, and could cause a severe allergic reaction. Your doctor will prescribe an alternative if necessary.
Additional Information
ANOXINCLAV 375 TAB, a combination of Amoxicillin and Clavulanic Acid, stands as a reliable and effective broad-spectrum antibiotic for treating various bacterial infections. Its unique formulation helps overcome antibiotic resistance, making it a powerful tool against challenging pathogens. By targeting bacterial cell wall synthesis and inhibiting resistance enzymes, it ensures comprehensive antibacterial action. It is crucial to adhere strictly to the prescribed dosage and complete the full course of treatment to achieve optimal results and prevent the development of antibiotic resistance. While generally well-tolerated, awareness of potential side effects and necessary precautions, especially regarding allergies, kidney, and liver health, is important. Always consult your healthcare provider for personalized medical advice and to address any concerns regarding your treatment with ANOXINCLAV 375 TAB.
