ONDETAS-8 MG TAB

Uses of ONDETAS-8 MG TAB

ONDETAS-8 MG TAB is primarily used to prevent and treat nausea and vomiting associated with various medical conditions and treatments.

• Chemotherapy-Induced Nausea and Vomiting (CINV)

  This medication is highly effective in preventing and treating severe nausea and vomiting caused by cancer chemotherapy. It helps patients tolerate their treatment better and reduces distress, allowing them to complete their therapeutic regimen with greater comfort and fewer side effects.

• Radiotherapy-Induced Nausea and Vomiting (RINV)

  ONDETAS-8 MG TAB is also indicated for the prevention of nausea and vomiting induced by radiation therapy, particularly when the radiation targets the abdomen. It helps manage the gastrointestinal side effects of radiation, improving patient compliance and overall treatment experience.

• Post-Operative Nausea and Vomiting (PONV)

  Administered before or after surgery, ONDETAS-8 MG TAB effectively prevents and treats nausea and vomiting that commonly occur after surgical procedures and anesthesia. This helps in a smoother recovery, reduces the risk of complications like wound dehiscence, and enhances patient satisfaction.

Side Effects of ONDETAS-8 MG TAB

Like all medicines, ONDETAS-8 MG TAB can cause side effects, although not everybody gets them. Most side effects are mild and temporary.

Serious side effects are rare but require immediate medical attention.

If you experience any severe or persistent side effects, or if you notice any other unusual symptoms, consult your doctor immediately. Do not self-medicate or alter your dosage without medical advice.

How to use ONDETAS-8 MG TAB

• Adults:

  For chemotherapy-induced nausea, typically 8 mg orally 30 minutes before chemotherapy, followed by 8 mg every 8-12 hours for up to 5 days. For radiotherapy-induced nausea, 8 mg orally 1-2 hours before radiation, then 8 mg every 8 hours. For post-operative nausea, 16 mg orally one hour before anesthesia, or 8 mg orally after surgery as directed by your physician.

• Children:

  Dosage for children depends on their body surface area (BSA) or weight and the specific condition being treated. For CINV, typically 4-8 mg orally 30 minutes before chemotherapy, repeated as needed. Always follow the pediatrician's instructions precisely regarding dosage and frequency.

• Elderly:

  No specific dose adjustment is generally required for elderly patients unless there is severe liver impairment. However, caution is advised, and a doctor should assess individual patient conditions. Close monitoring for side effects is recommended.

• Missed Dose:

  If you miss a dose of ONDETAS-8 MG TAB, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.

How ONDETAS-8 MG TAB works

Ondansetron, the active ingredient in ONDETAS-8 MG TAB, works by selectively blocking serotonin 5-HT3 receptors. Serotonin is a natural substance in the body that can cause nausea and vomiting. These 5-HT3 receptors are found in the gastrointestinal tract and in the chemoreceptor trigger zone (CTZ) in the brain, which is responsible for initiating the vomiting reflex. When certain stimuli, such as chemotherapy, radiation, or surgery, trigger the release of serotonin, it binds to these 5-HT3 receptors, leading to nausea and vomiting. By blocking these receptors, Ondansetron prevents serotonin from exerting its effects, thereby inhibiting the signals that lead to emesis. This targeted action makes ONDETAS-8 MG TAB highly effective in controlling various forms of nausea and vomiting.

Precautions

• Inform your doctor if you have liver disease, as dose adjustment may be necessary.
• Patients with heart problems, including a history of QT prolongation, should use with caution.
• Monitor electrolyte levels, especially potassium and magnesium, as imbalances can increase cardiac risk.
• Use with caution in patients with signs of subacute intestinal obstruction, as Ondansetron can decrease gut motility.
• Individuals with phenylketonuria should be aware that some formulations may contain aspartame.
• Avoid use in patients with known hypersensitivity to Ondansetron or any component of the tablet.

Safety Advice

Alcohol

CAUTION

Consuming alcohol while taking ONDETAS-8 MG TAB may increase the risk of side effects such as dizziness or drowsiness. It is advisable to limit or avoid alcohol intake during treatment to ensure optimal efficacy and safety.

Pregnancy

CONSULT YOUR DOCTOR

ONDETAS-8 MG TAB should be used during pregnancy only if clearly needed and after careful consideration of the benefits and risks by a doctor. While studies have shown varying results, it's crucial to consult your healthcare provider before use.

Breastfeeding

CONSULT YOUR DOCTOR

It is not known whether Ondansetron passes into breast milk. Therefore, breastfeeding mothers should consult their doctor before taking ONDETAS-8 MG TAB to weigh the potential risks to the infant against the benefits to the mother.

Driving

CAUTION

ONDETAS-8 MG TAB may cause dizziness or fatigue in some individuals. If you experience these symptoms, avoid driving or operating heavy machinery until you are sure you can perform such activities safely.

Kidney

SAFE IF PRESCRIBED

Dose adjustment for ONDETAS-8 MG TAB is generally not required for patients with kidney impairment. However, it is always best to inform your doctor about any kidney conditions you have before starting this medication.

Liver

CAUTION

Patients with moderate to severe liver impairment may require a reduced dose of ONDETAS-8 MG TAB. Your doctor will assess your liver function and adjust the dosage accordingly to prevent accumulation and potential side effects.

Fact Box

Frequently asked questions by patients

Frequently Asked Questions

Additional Information