Pain Relievers
ZOXOPAN-SP TAB A/A
SALT COMPOSITION
ACECLOFENAC 100+PCM 325MG+SERRATIOPEPTIDASE 10 MG TABTYPE
TABLET
STORAGE
Store below 25°C in a cool, dry place, protected from direct sunlight and moisture. Keep out of reach of children.
PRODUCT INTRODUCTION
ZOXOPAN-SP TAB A/A is a powerful combination medication widely prescribed in India for effective relief from pain and inflammation. This tablet combines Aceclofenac, a potent Non-Steroidal Anti-inflammatory Drug (NSAID), with Paracetamol (PCM), a well-known analgesic and antipyretic, and Serratiopeptidase, an enzyme with anti-inflammatory and anti-swelling properties. It is specifically formulated to address various painful conditions such as osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and post-operative pain, offering comprehensive relief and improved mobility.
Uses of ZOXOPAN-SP TAB A/A
ZOXOPAN-SP TAB A/A is indicated for the symptomatic treatment of various painful and inflammatory conditions.
- Osteoarthritis
Provides significant relief from joint pain, stiffness, and inflammation associated with osteoarthritis, improving joint function and quality of life. It targets the underlying inflammatory processes.
- Rheumatoid Arthritis
Effectively reduces pain, swelling, and morning stiffness in patients suffering from rheumatoid arthritis, helping to manage chronic inflammatory symptoms and improve daily activities.
- Ankylosing Spondylitis
Alleviates back pain and stiffness characteristic of ankylosing spondylitis, enhancing spinal mobility and reducing discomfort, thereby improving the patient's posture and movement.
- Post-operative Pain
Manages moderate to severe pain and inflammation following surgical procedures, aiding in faster recovery and patient comfort by reducing post-surgical swelling and pain signals.
- Musculoskeletal Pain
Useful in treating various musculoskeletal pains, including sprains, strains, and low back pain, by reducing inflammation and providing analgesic effects for quick relief.
Side Effects of ZOXOPAN-SP TAB A/A
Like all medicines, ZOXOPAN-SP TAB A/A can cause side effects, although not everybody gets them. Most side effects are mild and temporary.
Common side effects
- Nausea
- Vomiting
- Stomach pain
- Indigestion
- Diarrhea
- Dizziness
- Heartburn
Seek immediate medical attention if you experience any of the following rare but serious side effects.
- Severe allergic reactions (rash, itching, swelling)
- Liver problems (yellowing of skin/eyes)
- Kidney problems (changes in urine output)
- Gastrointestinal bleeding (black, tarry stools)
- Unusual bruising or bleeding
If any side effect persists or worsens, or if you notice any other side effects not listed here, please consult your doctor immediately for proper evaluation and management.
How to use ZOXOPAN-SP TAB A/A
- Adults:
Typically, one tablet twice daily, preferably after meals, or as directed by the physician. Do not exceed the prescribed dose or duration to avoid adverse effects.
- Children:
This medication is generally not recommended for children due to the specific dosage of its components. Consult a pediatrician for appropriate alternatives if needed for pediatric pain management.
- Elderly:
Elderly patients may be more susceptible to side effects. A lower dose or extended dosing interval may be considered by the physician, with close monitoring of kidney and liver function.
- Missed Dose:
If you miss a dose, take it as soon as you remember. If it's almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to compensate.
How ZOXOPAN-SP TAB A/A works
ZOXOPAN-SP TAB A/A works through a multi-pronged approach to combat pain and inflammation. Aceclofenac primarily acts by inhibiting the production of prostaglandins, chemical messengers in the body responsible for pain, inflammation, and fever. By blocking cyclooxygenase (COX) enzymes, it reduces swelling and pain effectively. Paracetamol, or Acetaminophen, works predominantly on the central nervous system to elevate the pain threshold and reduce fever, without significant anti-inflammatory action in the periphery. Serratiopeptidase, a proteolytic enzyme, helps in breaking down abnormal proteins at the site of inflammation, reducing swelling, improving fluid drainage, and promoting tissue repair. It also aids in reducing pain by decreasing the release of pain-inducing substances. The synergistic action of these three components provides superior pain relief and faster recovery compared to individual therapies, making ZOXOPAN-SP a comprehensive solution for inflammatory pain.
Precautions
- Inform your doctor about any existing medical conditions, especially liver, kidney, or heart disease, or a history of stomach ulcers.
- Avoid alcohol consumption while taking this medication to prevent increased risk of liver damage and stomach bleeding.
- Do not take this medicine if you are pregnant or breastfeeding without consulting your doctor, as it may pose risks.
- Inform your doctor about all other medications, including over-the-counter drugs and herbal supplements, to avoid potential drug interactions.
- Use with caution in patients with a history of gastrointestinal ulcers or bleeding, as NSAIDs can exacerbate these conditions.
- Discontinue use and consult a doctor if you experience any signs of allergic reaction (e.g., rash, difficulty breathing) or severe stomach pain.
Safety Advice
Alcohol
UNSAFEConsumption of alcohol with ZOXOPAN-SP TAB A/A can increase the risk of liver damage due to Paracetamol and heighten the risk of stomach bleeding associated with Aceclofenac. It is strongly advised to avoid alcohol during treatment.
Pregnancy
UNSAFEThis medication is generally not recommended during pregnancy, especially in the third trimester, as NSAIDs can harm the developing baby and complicate delivery. Always consult your doctor before use if you are pregnant or planning a pregnancy.
Breastfeeding
CONSULT YOUR DOCTORComponents of ZOXOPAN-SP TAB A/A may pass into breast milk and could potentially affect the nursing infant. It is crucial to consult your doctor to weigh the benefits against the risks before breastfeeding.
Driving
CAUTIONZOXOPAN-SP TAB A/A may cause dizziness or drowsiness in some individuals. If you experience these symptoms, avoid driving or operating heavy machinery until you are sure you can perform such activities safely.
Kidney
CAUTIONUse with caution in patients with kidney disease. Aceclofenac can affect kidney function, especially in patients with pre-existing conditions. Regular monitoring of kidney function may be required by your doctor.
Liver
CAUTIONPatients with liver impairment should use ZOXOPAN-SP TAB A/A with caution. Both Aceclofenac and Paracetamol are metabolized in the liver, and high doses or prolonged use can exacerbate liver conditions. Liver function tests may be advised.
Fact Box
Frequently asked questions by patients
Q: Can ZOXOPAN-SP TAB A/A be taken on an empty stomach?
A: It is generally recommended to take ZOXOPAN-SP TAB A/A after meals or with food to minimize the risk of stomach upset and irritation, which is common with NSAIDs like Aceclofenac. Always follow your doctor's advice for optimal safety.
Q: How long should I take ZOXOPAN-SP TAB A/A?
A: The duration of treatment with ZOXOPAN-SP TAB A/A depends on your medical condition and response to therapy. It should be used for the shortest possible duration and at the lowest effective dose. Do not exceed the prescribed period without consulting your doctor.
Q: Is ZOXOPAN-SP TAB A/A safe for long-term use?
A: Long-term use of ZOXOPAN-SP TAB A/A should be avoided due to potential risks of gastrointestinal bleeding, kidney issues, and cardiovascular side effects associated with NSAIDs and Paracetamol. Your doctor will assess the risks and benefits for prolonged therapy.
Q: Can I take other pain relievers with ZOXOPAN-SP TAB A/A?
A: It is not advisable to take other pain relievers, especially other NSAIDs or Paracetamol-containing medicines, concurrently with ZOXOPAN-SP TAB A/A. This can lead to an overdose of components and increase the risk of severe side effects. Always consult your doctor before combining medications.
Frequently Asked Questions
Q: What is ZOXOPAN-SP TAB A/A used for?
ZOXOPAN-SP TAB A/A is a combination medication used to relieve pain and inflammation associated with various conditions such as osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and post-operative pain. It helps reduce swelling, stiffness, and discomfort to improve mobility and quality of life.
Q: How does ZOXOPAN-SP TAB A/A work?
This tablet contains Aceclofenac, which reduces pain and inflammation by inhibiting prostaglandins; Paracetamol, which acts as an analgesic and antipyretic; and Serratiopeptidase, an enzyme that reduces swelling and aids tissue repair. Together, they provide comprehensive relief from inflammatory pain through a synergistic mechanism.
Q: What are the common side effects of ZOXOPAN-SP TAB A/A?
Common side effects may include nausea, vomiting, stomach pain, indigestion, diarrhea, dizziness, and heartburn. These are usually mild and temporary. If they persist or worsen, or if you experience any unusual symptoms, consult your doctor immediately for advice.
Q: Can ZOXOPAN-SP TAB A/A be given to children?
No, ZOXOPAN-SP TAB A/A is generally not recommended for children. The dosage and composition are formulated for adults. Always consult a pediatrician for appropriate pain relief options for children, as different formulations and dosages are required for pediatric patients.
Q: What precautions should I take while using ZOXOPAN-SP TAB A/A?
Inform your doctor about any existing liver, kidney, or heart conditions. Avoid alcohol consumption during treatment. Do not use if pregnant or breastfeeding without medical advice. Be cautious if you have a history of stomach ulcers or bleeding. Always disclose all other medications you are taking to prevent interactions.
Additional Information
ZOXOPAN-SP TAB A/A offers a robust solution for managing pain and inflammation, leveraging the combined power of Aceclofenac, Paracetamol, and Serratiopeptidase. This triple-action formula targets pain, reduces swelling, and promotes healing, making it highly effective for conditions like arthritis, spondylitis, and post-surgical discomfort. Its comprehensive approach aims to restore comfort and improve the quality of life for patients. However, like all potent medications, it is crucial to use ZOXOPAN-SP TAB A/A strictly under medical supervision. Adherence to prescribed dosages and duration is vital to minimize potential side effects and ensure optimal therapeutic outcomes. Always consult your healthcare provider for personalized advice and to address any concerns regarding its use, ensuring a safe and effective treatment experience.

