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Pain Relievers
ZOXOPAN PLUS TAB BLISTER
SALT COMPOSITION
ACECLOFENAC 100+PCM 325MGTYPE
TABLET
STORAGE
Store below 25°C, protect from light and moisture. Keep out of reach of children.
PRODUCT INTRODUCTION
ZOXOPAN PLUS TAB BLISTER is a powerful combination medication designed to provide effective relief from pain, inflammation, and fever. Each tablet contains Aceclofenac 100mg, a non-steroidal anti-inflammatory drug (NSAID), and Paracetamol (PCM) 325mg, a well-known analgesic and antipyretic. This synergistic formulation targets various types of pain, including those associated with musculoskeletal conditions like osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis, as well as general body aches, dental pain, and post-operative discomfort. ZOXOPAN PLUS is an essential choice for managing acute and chronic painful inflammatory conditions, helping patients regain comfort and improve their quality of life.
Uses of ZOXOPAN PLUS TAB BLISTER
ZOXOPAN PLUS TAB BLISTER is prescribed for the effective management of various painful and inflammatory conditions.
- Rheumatoid Arthritis
This medication provides significant relief from the pain, inflammation, and tenderness characteristic of rheumatoid arthritis, an autoimmune inflammatory disorder. By targeting the inflammatory pathways, it helps manage flare-ups and improve the quality of life for individuals with RA.
- Ankylosing Spondylitis
ZOXOPAN PLUS is used to alleviate the chronic pain and inflammation in the spine and large joints caused by ankylosing spondylitis. It helps in reducing stiffness, particularly in the morning, and improves spinal mobility, contributing to better posture and reduced discomfort.
Side Effects of ZOXOPAN PLUS TAB BLISTER
Like all medicines, ZOXOPAN PLUS can cause side effects, although not everybody gets them. Most side effects are mild and temporary.
Common side effects
- Nausea
- Vomiting
- Stomach pain
- Indigestion
- Diarrhea
- Dizziness
- Headache
- Heartburn
Less commonly, some individuals may experience more serious side effects. Seek immediate medical attention if any severe symptoms occur.
- Gastrointestinal bleeding
- Liver damage
- Kidney problems
- Allergic reactions (rash, itching, swelling)
If any side effect bothers you or persists, please consult your doctor. Do not stop taking the medicine without consulting your healthcare provider.
How to use ZOXOPAN PLUS TAB BLISTER
- Adults:
Typically, one tablet twice daily, preferably after meals, or as directed by a physician. Do not exceed the recommended dose.
- Children:
Not recommended for children under 18 years of age without specific medical advice. Pediatric dosing should be determined by a specialist.
- Elderly:
Elderly patients should use with caution and may require a lower dose due to increased risk of side effects, especially gastrointestinal and renal issues. Consult a doctor for appropriate dosing.
- Missed Dose:
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
How ZOXOPAN PLUS TAB BLISTER works
ZOXOPAN PLUS works through a dual mechanism to alleviate pain and inflammation. Aceclofenac, an NSAID, primarily acts by inhibiting the production of prostaglandins, which are chemical mediators responsible for pain, inflammation, and fever. It achieves this by blocking the cyclooxygenase (COX) enzymes, particularly COX-2, leading to reduced inflammatory responses and pain signals. Paracetamol, on the other hand, exerts its analgesic and antipyretic effects mainly through central action. While its exact mechanism is not fully understood, it is believed to inhibit prostaglandin synthesis in the central nervous system and act on thermoregulatory centers in the brain, thereby reducing fever and pain perception without significant anti-inflammatory effects in the periphery. The combination ensures comprehensive relief by tackling both inflammatory pain and general discomfort.
Precautions
- Inform your doctor if you have a history of stomach ulcers, bleeding disorders, or inflammatory bowel disease.
- Use with caution in patients with kidney or liver impairment.
- Avoid concomitant use with other NSAIDs or paracetamol-containing products to prevent overdose.
- Patients with a history of asthma, allergic reactions, or cardiovascular disease should use this medication under strict medical supervision.
- Do not exceed the prescribed dose or duration of treatment.
- Discontinue use and consult a doctor if you experience any signs of liver damage (e.g., dark urine, yellowing of skin/eyes).
Safety Advice
Alcohol
UNSAFEConsumption of alcohol while taking ZOXOPAN PLUS is unsafe. It can increase the risk of stomach bleeding and liver damage, especially due to the paracetamol component. Avoid alcohol during treatment.
Pregnancy
UNSAFEZOXOPAN PLUS is generally not recommended during pregnancy, especially in the third trimester, as Aceclofenac can harm the developing baby and complicate delivery. Consult your doctor immediately if you are pregnant or planning pregnancy.
Breastfeeding
CONSULT YOUR DOCTORBoth Aceclofenac and Paracetamol pass into breast milk. While paracetamol is generally considered safe, NSAIDs should be used with caution. Consult your doctor to weigh the benefits against potential risks before breastfeeding.
Driving
CAUTIONZOXOPAN PLUS may cause dizziness, drowsiness, or visual disturbances in some individuals. If you experience these symptoms, avoid driving or operating heavy machinery until you feel well enough.
Kidney
CAUTIONUse ZOXOPAN PLUS with caution in patients with kidney disease. Aceclofenac can affect kidney function, especially with prolonged use or in dehydrated individuals. Regular monitoring of kidney function may be required.
Liver
CAUTIONZOXOPAN PLUS should be used with caution in patients with liver disease. Paracetamol, in particular, can cause liver damage in high doses or with pre-existing liver conditions. Close medical supervision and dose adjustments may be necessary.
Fact Box
Frequently asked questions by patients
Q: Can ZOXOPAN PLUS be taken on an empty stomach?
A: It is generally recommended to take ZOXOPAN PLUS after meals or with food to minimize the risk of stomach upset and irritation, which can be a common side effect of NSAIDs like Aceclofenac. Always follow your doctor's advice.
Q: How long can I take ZOXOPAN PLUS?
A: The duration of treatment with ZOXOPAN PLUS should be as short as possible and at the lowest effective dose. Prolonged use, especially of NSAIDs, can increase the risk of side effects. Your doctor will determine the appropriate duration based on your condition.
Q: Is ZOXOPAN PLUS safe for individuals with heart conditions?
A: Patients with pre-existing heart conditions, such as heart failure or a history of heart attack, should use ZOXOPAN PLUS with extreme caution and under strict medical supervision. NSAIDs can increase the risk of cardiovascular events. Consult your cardiologist.
Q: What should I do if I experience severe stomach pain after taking ZOXOPAN PLUS?
A: If you experience severe stomach pain, black or tarry stools, or vomit that looks like coffee grounds, stop taking ZOXOPAN PLUS immediately and seek urgent medical attention. These could be signs of serious gastrointestinal bleeding.
Frequently Asked Questions
Q: What is ZOXOPAN PLUS TAB BLISTER used for?
ZOXOPAN PLUS TAB BLISTER is primarily used to relieve various types of pain, reduce inflammation, and bring down fever. It is commonly prescribed for conditions like osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, dental pain, and general body aches. Its dual action helps manage both acute and chronic discomfort effectively.
Q: How does ZOXOPAN PLUS work to relieve pain?
ZOXOPAN PLUS contains Aceclofenac and Paracetamol. Aceclofenac works by blocking the production of certain natural substances in the body (prostaglandins) that cause inflammation and pain. Paracetamol acts centrally in the brain to raise the pain threshold and reduce fever. Together, they provide comprehensive pain and inflammation relief.
Q: Are there any specific dietary restrictions while taking ZOXOPAN PLUS?
While there are no strict dietary restrictions, it is advisable to take ZOXOPAN PLUS with food or milk to reduce the chances of stomach upset. Avoiding alcohol is crucial as it can increase the risk of liver damage and gastrointestinal bleeding when combined with this medication. Always follow your doctor's specific advice.
Q: Can ZOXOPAN PLUS be taken with other pain medications?
It is generally not recommended to take ZOXOPAN PLUS with other NSAIDs or paracetamol-containing medications without consulting your doctor. Combining them can lead to an overdose of either component, increasing the risk of severe side effects, especially liver or kidney damage. Always inform your doctor about all medications you are taking.
Q: What are the common side effects of ZOXOPAN PLUS?
Common side effects of ZOXOPAN PLUS include nausea, vomiting, stomach pain, indigestion, diarrhea, dizziness, and headache. These are usually mild and temporary. If any of these effects persist or worsen, or if you experience any severe or unusual symptoms, it is important to consult your doctor immediately.
Additional Information
ZOXOPAN PLUS TAB BLISTER offers a robust solution for individuals grappling with pain, inflammation, and fever. Combining the potent anti-inflammatory action of Aceclofenac with the analgesic and antipyretic properties of Paracetamol, this medication provides comprehensive relief for a wide range of conditions, from chronic joint disorders like osteoarthritis and rheumatoid arthritis to acute musculoskeletal pain. Its carefully balanced formulation aims to improve patient comfort and mobility, facilitating a better quality of life. While highly effective, it is crucial to adhere strictly to the prescribed dosage and duration of treatment to minimize potential side effects. Patients should be mindful of precautions, especially concerning gastrointestinal health, kidney, and liver function, and always consult their healthcare provider for personalized advice. ZOXOPAN PLUS represents a valuable therapeutic option in pain management, empowering patients to manage their symptoms effectively under medical guidance.
