Pain Relievers
ZOXOPAN PLUS TAB A/A
SALT COMPOSITION
ACECLOFENAC 100+PCM 325MGTYPE
TABLET
STORAGE
Store ZOXOPAN PLUS TAB A/A below 25°C in a cool, dry place. Protect from direct sunlight and moisture. Keep out of reach of children and pets.
PRODUCT INTRODUCTION
ZOXOPAN PLUS TAB A/A is a powerful combination medication designed to provide effective relief from pain, inflammation, and fever. It contains Aceclofenac, a non-steroidal anti-inflammatory drug (NSAID), and Paracetamol (PCM), a well-known analgesic and antipyretic. This synergistic formulation targets multiple pathways of pain and inflammation, making it highly effective for conditions like osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and other painful musculoskeletal disorders. ZOXOPAN PLUS TAB A/A helps improve mobility and quality of life by reducing discomfort and swelling, allowing patients to resume daily activities with greater ease. Always consult your doctor for proper diagnosis and dosage.
Uses of ZOXOPAN PLUS TAB A/A
ZOXOPAN PLUS TAB A/A is indicated for the symptomatic treatment of various painful and inflammatory conditions. It is particularly useful in managing chronic inflammatory diseases and acute painful states.
- Osteoarthritis
This medication helps alleviate the pain, stiffness, and swelling associated with osteoarthritis, a degenerative joint disease. It improves joint mobility and reduces discomfort, allowing patients to perform daily activities with greater ease. Regular use under medical supervision can significantly enhance the quality of life for individuals suffering from this condition.
- Rheumatoid Arthritis
ZOXOPAN PLUS TAB A/A is effective in reducing the pain, inflammation, and morning stiffness characteristic of rheumatoid arthritis, a chronic autoimmune inflammatory disorder affecting joints. It helps in managing the symptoms, thereby improving joint function and overall comfort for patients. Adherence to prescribed dosage is crucial for optimal results.
- Ankylosing Spondylitis
For patients with ankylosing spondylitis, a chronic inflammatory disease primarily affecting the spine, this tablet provides significant relief from back pain and stiffness. It helps in reducing inflammation in the spinal joints, leading to improved flexibility and reduced discomfort. Consistent use as directed by a physician is recommended for long-term management.
Side Effects of ZOXOPAN PLUS TAB A/A
Like all medicines, ZOXOPAN PLUS TAB A/A can cause side effects, although not everybody gets them. Most side effects are mild and temporary, but some can be serious. If any of the side effects bother you or do not go away, please consult your doctor.
Common side effects
- Nausea
- Vomiting
- Stomach pain/Indigestion
- Diarrhea
- Dizziness
Less common or rare side effects may include more severe reactions. Seek immediate medical attention if you experience any of these:
- Gastrointestinal bleeding/Ulcers
- Liver or kidney problems
- Severe allergic reactions (rash, itching, swelling)
- Blood disorders (e.g., anemia)
- Heart problems (e.g., heart attack, stroke) with long-term high dose use
It is important to report any unusual or severe symptoms to your doctor immediately. Do not discontinue the medication without consulting your healthcare provider.
How to use ZOXOPAN PLUS TAB A/A
- Adults:
Typically, one tablet twice daily, preferably after meals, or as directed by your physician. Do not exceed the recommended dose. The duration of treatment should be as short as possible and not exceed the period necessary for symptom control.
- Children:
The use of ZOXOPAN PLUS TAB A/A in children is generally not recommended. Pediatric dosing should only be considered under strict medical supervision, and alternative medications may be preferred. Always consult a pediatrician before administering any medication to children.
- Elderly:
Elderly patients may be more susceptible to side effects, especially gastrointestinal bleeding and kidney impairment. A lower dosage or extended dosing interval may be required. Close monitoring by a healthcare professional is advisable. Use with caution and only as prescribed.
- Missed Dose:
If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.
How ZOXOPAN PLUS TAB A/A works
ZOXOPAN PLUS TAB A/A works through the combined actions of its two active ingredients. Aceclofenac, an NSAID, primarily functions by inhibiting the cyclooxygenase (COX) enzymes, specifically COX-2, which are responsible for the synthesis of prostaglandins. Prostaglandins are chemical mediators that play a crucial role in initiating and maintaining inflammation, pain, and fever. By reducing prostaglandin production, Aceclofenac effectively diminishes inflammatory responses and alleviates pain. Paracetamol (PCM), on the other hand, exerts its analgesic and antipyretic effects mainly through central mechanisms. It is believed to inhibit prostaglandin synthesis predominantly in the central nervous system, thereby raising the pain threshold and acting on the hypothalamic heat-regulating center to produce antipyresis (fever reduction). The combination of Aceclofenac and Paracetamol in ZOXOPAN PLUS TAB A/A provides a comprehensive approach to pain and inflammation management, offering enhanced efficacy compared to either component alone.
Precautions
- Inform your doctor if you have a history of stomach ulcers, bleeding disorders, or gastrointestinal problems.
- Use with caution in patients with kidney or liver impairment; dose adjustments may be necessary.
- Patients with heart conditions, high blood pressure, or a history of stroke should use this medication cautiously.
- Avoid concomitant use with other NSAIDs or paracetamol-containing products to prevent overdose.
- Inform your doctor about all other medications you are taking, including herbal supplements, to avoid potential drug interactions.
- This medication may cause dizziness or drowsiness; avoid driving or operating heavy machinery until you know how it affects you.
Safety Advice
Alcohol
UNSAFEConsumption of alcohol while taking ZOXOPAN PLUS TAB A/A is unsafe. It can significantly increase the risk of liver damage due to Paracetamol and heighten the risk of stomach bleeding associated with Aceclofenac.
Pregnancy
UNSAFEZOXOPAN PLUS TAB A/A is generally unsafe during pregnancy, especially in the third trimester, as it may harm the developing baby and cause complications during delivery. Consult your doctor before use if you are pregnant or planning a pregnancy.
Breastfeeding
CONSULT YOUR DOCTORThe components of ZOXOPAN PLUS TAB A/A may pass into breast milk and could potentially affect the nursing infant. It is advisable to consult your doctor before using this medication during breastfeeding to weigh the benefits against potential risks.
Driving
CAUTIONZOXOPAN PLUS TAB A/A may cause dizziness, drowsiness, or visual disturbances in some individuals. If you experience these symptoms, avoid driving or operating heavy machinery until you are certain you can do so safely.
Kidney
CAUTIONUse ZOXOPAN PLUS TAB A/A with caution in patients with pre-existing kidney disease. Aceclofenac can affect kidney function, especially with prolonged use or in dehydrated individuals. Regular monitoring of kidney function is recommended.
Liver
CAUTIONPatients with liver disease should use ZOXOPAN PLUS TAB A/A with caution. Both Aceclofenac and Paracetamol are metabolized in the liver, and impaired liver function can increase the risk of adverse effects. Liver function tests may be required during treatment.
Fact Box
Frequently asked questions by patients
Q: Can I take ZOXOPAN PLUS TAB A/A on an empty stomach?
A: It is generally recommended to take ZOXOPAN PLUS TAB A/A after meals or with food to minimize the risk of gastrointestinal upset, which is a common side effect of NSAIDs like Aceclofenac. Always follow your doctor's advice.
Q: Is ZOXOPAN PLUS TAB A/A safe for long-term use?
A: Long-term use of ZOXOPAN PLUS TAB A/A should be avoided unless specifically prescribed by your doctor. Prolonged use of NSAIDs can increase the risk of serious side effects, including gastrointestinal bleeding, kidney problems, and cardiovascular events. Your doctor will determine the appropriate duration of treatment.
Q: What if I experience stomach pain after taking this medicine?
A: If you experience severe stomach pain, indigestion, or any signs of gastrointestinal bleeding (like black, tarry stools or vomiting blood), stop taking ZOXOPAN PLUS TAB A/A immediately and consult your doctor. Taking it with food can help reduce mild discomfort.
Q: Can ZOXOPAN PLUS TAB A/A be used for fever only?
A: While ZOXOPAN PLUS TAB A/A contains Paracetamol, which is an antipyretic, it also contains Aceclofenac, an NSAID. For fever alone, a single-ingredient paracetamol preparation might be more appropriate. Use ZOXOPAN PLUS TAB A/A when both pain/inflammation and fever are present, as prescribed by your doctor.
Frequently Asked Questions
Q: What is ZOXOPAN PLUS TAB A/A used for?
ZOXOPAN PLUS TAB A/A is primarily used to relieve pain, reduce inflammation, and lower fever associated with various conditions. It is commonly prescribed for musculoskeletal pains, joint disorders like osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and other painful inflammatory conditions. Its dual-action formula provides comprehensive relief.
Q: How quickly does ZOXOPAN PLUS TAB A/A start working?
The effects of ZOXOPAN PLUS TAB A/A typically begin within 30 to 60 minutes after administration. The peak pain-relieving and anti-inflammatory effects may be observed within 1-3 hours. Individual response may vary based on the condition being treated and the patient's metabolism.
Q: Are there any specific dietary restrictions while taking this medicine?
There are no specific dietary restrictions, but it is advisable to take ZOXOPAN PLUS TAB A/A with food or milk to minimize gastrointestinal irritation. Avoid consuming alcohol as it can increase the risk of side effects. Maintain a balanced diet and stay hydrated.
Q: Can I take ZOXOPAN PLUS TAB A/A with other pain relievers?
It is not recommended to take ZOXOPAN PLUS TAB A/A with other NSAIDs (like ibuprofen, naproxen) or other paracetamol-containing medications without consulting your doctor. Combining these can increase the risk of overdose and severe side effects, especially affecting the liver and stomach. Always inform your doctor about all medications you are taking.
Q: What should I do if I experience an allergic reaction?
If you experience signs of an allergic reaction such as rash, itching, swelling of the face, lips, tongue, or throat, severe dizziness, or trouble breathing, stop taking ZOXOPAN PLUS TAB A/A immediately and seek urgent medical attention. These could be signs of a serious allergic response.
Additional Information
ZOXOPAN PLUS TAB A/A stands as an effective solution for managing a wide spectrum of painful and inflammatory conditions, including chronic joint disorders and acute musculoskeletal pain. Its well-balanced combination of Aceclofenac and Paracetamol offers both anti-inflammatory and analgesic properties, providing significant relief from discomfort and improving functional mobility. This medication is a valuable tool in the symptomatic management of conditions that impact daily life, helping patients regain comfort and maintain an active lifestyle. However, it is crucial to remember that ZOXOPAN PLUS TAB A/A is a prescription medication and should be used strictly under the guidance of a healthcare professional. Adherence to the prescribed dosage and duration is paramount to maximize benefits while minimizing potential risks. Patients should be vigilant about potential side effects and promptly report any concerns to their doctor. Regular follow-ups ensure that the treatment remains appropriate and effective for the individual's specific health needs. By understanding its uses, mechanism of action, and necessary precautions, patients can utilize ZOXOPAN PLUS TAB A/A responsibly to achieve optimal pain and inflammation control, contributing to an enhanced quality of life. Always prioritize consulting your physician for personalized medical advice and treatment plans.

