ZOXOPAN-MR TAB A/A

Uses of ZOXOPAN-MR TAB A/A

ZOXOPAN-MR TAB A/A is indicated for the symptomatic treatment of various painful conditions, particularly those involving inflammation and muscle spasms.

• Musculoskeletal Pain

  Effective in relieving pain and inflammation associated with conditions like sprains, strains, low back pain, and other soft tissue injuries. It helps reduce discomfort and swelling, promoting faster recovery and improved function.

• Osteoarthritis and Rheumatoid Arthritis

  Provides significant relief from the pain, stiffness, and inflammation characteristic of chronic arthritic conditions. The anti-inflammatory action of Aceclofenac, combined with the analgesic effect of Paracetamol, helps manage daily symptoms effectively.

• Cervical Spondylosis and Fibromyalgia

  Addresses the chronic pain and muscle stiffness experienced in conditions like cervical spondylosis and fibromyalgia. Chlorzoxazone's muscle relaxant properties are particularly beneficial in alleviating muscle spasms and improving mobility in these conditions.

Side Effects of ZOXOPAN-MR TAB A/A

Like all medications, ZOXOPAN-MR TAB A/A can cause side effects, although not everyone experiences them. Most side effects are mild and temporary.

While less common, some serious side effects may occur, requiring immediate medical attention.

If any side effect persists or worsens, or if you experience any severe symptoms, consult your doctor immediately.

How to use ZOXOPAN-MR TAB A/A

• Adults:

  Typically, one tablet twice daily, preferably after meals, or as directed by a physician. The dosage should not exceed the recommended limits to avoid potential side effects.

• Children:

  Not recommended for children under 18 years of age without specific medical advice. Pediatric dosing requires careful consideration by a specialist due to potential risks.

• Elderly:

  Elderly patients may be more susceptible to side effects. A lower dosage or extended dosing interval may be considered, and close monitoring for adverse reactions is advised by a healthcare professional.

• Missed Dose:

  If a dose is missed, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to make up for a missed one.

How ZOXOPAN-MR TAB A/A works

ZOXOPAN-MR TAB A/A works through the combined actions of its three active ingredients. Aceclofenac primarily acts by inhibiting cyclooxygenase (COX) enzymes, particularly COX-2, which are responsible for the synthesis of prostaglandins – chemicals that mediate pain, inflammation, and fever. By reducing prostaglandin production, Aceclofenac effectively diminishes inflammation and pain. Paracetamol, while also an analgesic and antipyretic, works predominantly in the central nervous system by inhibiting prostaglandin synthesis, thereby elevating the pain threshold and reducing fever. Chlorzoxazone, a centrally acting muscle relaxant, works on the spinal cord and subcortical areas of the brain. It inhibits multisynaptic reflex arcs involved in producing and maintaining skeletal muscle spasms. This action helps to alleviate muscle stiffness, tension, and discomfort associated with various musculoskeletal conditions. The combination of these three agents provides a multi-pronged approach to pain management, addressing inflammation, pain, and muscle spasms simultaneously for enhanced therapeutic efficacy.

Precautions

• Inform your doctor about any pre-existing medical conditions, especially liver, kidney, or heart disease.
• Avoid alcohol consumption while taking this medication as it may increase the risk of liver damage and stomach bleeding.
• Do not exceed the prescribed dose or duration of treatment.
• Use with caution in patients with a history of gastrointestinal ulcers or bleeding.
• May cause dizziness or drowsiness; avoid driving or operating heavy machinery if affected.
• Not recommended during the third trimester of pregnancy due to potential risks to the fetus.

Safety Advice

Alcohol

UNSAFE

It is generally unsafe to consume alcohol with ZOXOPAN-MR TAB A/A. Alcohol can increase the risk of stomach bleeding and liver damage, especially with Paracetamol and Aceclofenac components.

Pregnancy

UNSAFE

This medication is generally unsafe during pregnancy, particularly in the third trimester, due to potential risks to the fetus and complications during delivery. Consult your doctor for alternatives.

Breastfeeding

CONSULT YOUR DOCTOR

The components of ZOXOPAN-MR TAB A/A may pass into breast milk. Consult your doctor to weigh the potential risks and benefits before breastfeeding.

Driving

CAUTION

ZOXOPAN-MR TAB A/A may cause dizziness or drowsiness due to Chlorzoxazone. Avoid driving or operating heavy machinery if you experience these symptoms.

Kidney

CAUTION

Use with caution in patients with kidney disease. Aceclofenac can affect kidney function. Regular monitoring of kidney parameters may be necessary as advised by your doctor.

Liver

CAUTION

This medication should be used with caution in patients with liver disease. Paracetamol and Aceclofenac can cause liver damage, especially with prolonged use or overdose. Liver function tests may be required.

Fact Box

Frequently asked questions by patients

Frequently Asked Questions

Additional Information