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Hepatoprotective
UDIBID 300MG (5%)
SALT COMPOSITION
URSODEOXYCHOLIC ACID 300MGTYPE
TABLET
STORAGE
Store below 30°C in a cool, dry place, away from direct sunlight and moisture. Keep out of reach of children.
PRODUCT INTRODUCTION
UDIBID 300MG Tablet, containing Ursodeoxycholic Acid, is a widely prescribed medication in India for various liver and gallbladder conditions. This potent hepatoprotective agent works by dissolving cholesterol gallstones and improving bile flow, thereby aiding liver function. It is particularly effective in managing conditions like primary biliary cholangitis (PBC) and preventing gallstone formation in certain patients. UDIBID 300MG is crucial for maintaining liver health and alleviating symptoms associated with impaired bile acid metabolism, offering a significant therapeutic benefit for patients seeking comprehensive gastrointestinal and liver care.
Uses of UDIBID 300MG (5%)
UDIBID 300MG is primarily used to treat and prevent various liver and gallbladder disorders.
- Primary Biliary Cholangitis (PBC)
For patients suffering from Primary Biliary Cholangitis (PBC), UDIBID 300MG is a first-line treatment. It helps to improve bile flow, protect liver cells from damage caused by toxic bile acids, and reduce inflammation. This leads to an improvement in liver function tests, delays disease progression, and enhances the quality of life for individuals with this chronic autoimmune liver disease.
- Biliary Reflux Gastritis
UDIBID 300MG can also be prescribed to manage biliary reflux gastritis, a condition where bile flows back into the stomach, causing irritation and inflammation. By altering the composition of bile and potentially reducing its irritant properties, Ursodeoxycholic Acid helps to alleviate symptoms such as epigastric pain, nausea, and vomiting associated with this condition, promoting gastric mucosal healing.
Side Effects of UDIBID 300MG (5%)
Like all medicines, UDIBID 300MG can cause side effects, although not everybody gets them. Most side effects are mild and temporary.
Common side effects
- Diarrhea
- Nausea
- Abdominal pain
- Indigestion
- Constipation
Rarely, more serious side effects may occur. Seek immediate medical attention if you experience any of these.
- Allergic reactions (rash, itching, swelling)
- Worsening of pre-existing liver conditions
- Calcification of gallstones
If any side effect bothers you or persists, please consult your doctor. Do not stop taking the medication without medical advice.
How to use UDIBID 300MG (5%)
- Adults:
For gallstone dissolution, typically 8-10 mg/kg/day in 2-3 divided doses, usually taken with meals. For Primary Biliary Cholangitis, 13-15 mg/kg/day in 2-4 divided doses. Treatment duration varies based on the condition and response. Always follow your doctor's instructions.
- Children:
Dosage should be determined by a pediatrician based on body weight and the specific condition being treated. It is crucial not to self-medicate and to seek professional medical advice for pediatric dosing.
- Elderly:
No specific dose adjustment is generally required for elderly patients, but caution should be exercised in those with significant comorbidities. Regular monitoring of liver function is advisable.
- Missed Dose:
If you miss a dose, take it as soon as you remember. If it's almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to make up for a missed one.
How UDIBID 300MG (5%) works
Ursodeoxycholic Acid (UDCA) primarily acts by reducing the cholesterol content of bile, leading to the dissolution of cholesterol gallstones. It achieves this by suppressing hepatic cholesterol synthesis and secretion, and by decreasing intestinal cholesterol absorption. Furthermore, UDCA increases the saturation of bile with bile acids, which helps to solubilize cholesterol. Beyond gallstone dissolution, UDCA exhibits cytoprotective and immunomodulatory effects. It replaces toxic bile acids in the bile acid pool, protecting liver cells from damage. In chronic cholestatic liver diseases like Primary Biliary Cholangitis (PBC), UDCA improves bile flow and reduces inflammation, thereby slowing disease progression and improving liver function tests. Its multifaceted action makes it a cornerstone in hepatobiliary therapy.
Precautions
- Do not take UDIBID 300MG if you have calcified gallstones, acute inflammation of the gallbladder or bile ducts, or blocked bile ducts.
- Inform your doctor if you have a history of liver disease other than the one being treated.
- Use with caution in patients with peptic ulcer disease.
- Regular monitoring of liver function tests (LFTs) is recommended during treatment.
- Avoid taking antacids containing aluminium hydroxide or cholesterol-lowering agents (like cholestyramine) simultaneously, as they can interfere with UDCA absorption.
- Inform your doctor about all other medications, supplements, and herbal products you are taking.
Safety Advice
Alcohol
CAUTIONConsuming alcohol while on UDIBID 300MG may worsen liver conditions and reduce the effectiveness of the medication. It is advisable to limit or avoid alcohol intake during treatment to support liver health.
Pregnancy
CONSULT YOUR DOCTORUDIBID 300MG should be used during pregnancy only if clearly needed and after careful consideration of the potential risks and benefits by your doctor. Animal studies have shown some adverse effects, but human data is limited.
Breastfeeding
CONSULT YOUR DOCTORIt is unknown whether Ursodeoxycholic Acid passes into breast milk. Consult your doctor before breastfeeding while taking UDIBID 300MG to weigh the potential risks to the infant against the benefits to the mother.
Driving
SAFEUDIBID 300MG is generally not known to impair your ability to drive or operate machinery. However, if you experience any side effects like dizziness that might affect your concentration, avoid such activities.
Kidney
SAFE IF PRESCRIBEDUDIBID 300MG is primarily metabolized by the liver and excreted via bile. It is generally considered safe for use in patients with kidney disease, but always consult your doctor, especially if you have severe renal impairment.
Liver
CONSULT YOUR DOCTORUDIBID 300MG is used to treat liver conditions, but its use should be carefully monitored in patients with severe liver dysfunction or acute liver inflammation. Regular liver function tests are essential during treatment.
Fact Box
Frequently asked questions by patients
Q: Can UDIBID 300MG be taken long-term?
A: Yes, UDIBID 300MG is often prescribed for long-term use, especially for conditions like Primary Biliary Cholangitis or for dissolving gallstones, which can take several months to years. Your doctor will determine the appropriate duration based on your condition and response to treatment.
Q: How long does it take for UDIBID 300MG to work?
A: For gallstone dissolution, it may take several months to a year or more to see significant results. For liver conditions like PBC, improvements in liver function tests can be observed within a few weeks to months, but the full therapeutic effect may take longer. Consistency is key.
Q: Can I stop taking UDIBID 300MG if I feel better?
A: No, do not stop taking UDIBID 300MG without consulting your doctor, even if your symptoms improve. Premature discontinuation, especially for gallstones, can lead to recurrence. Your doctor will advise on the appropriate time and method to discontinue the medication.
Q: What foods should I avoid while taking UDIBID 300MG?
A: While there are no specific foods to strictly avoid, a diet low in cholesterol and saturated fats can complement the action of UDIBID 300MG, especially when treating cholesterol gallstones. Consult your doctor or a dietitian for personalized dietary advice.
Frequently Asked Questions
Q: Is UDIBID 300MG effective for all types of gallstones?
UDIBID 300MG is primarily effective for dissolving cholesterol gallstones. It is not effective for calcified gallstones or pigment gallstones. Your doctor will perform diagnostic tests to determine the type of gallstones you have before prescribing this medication.
Q: Can UDIBID 300MG cause weight gain?
Weight gain is not a commonly reported side effect of UDIBID 300MG. If you experience unexplained weight changes, it is advisable to discuss this with your doctor, as it might be related to other factors or underlying conditions.
Q: What should I do if I experience severe diarrhea?
Severe diarrhea can be a side effect of UDIBID 300MG. If you experience persistent or severe diarrhea, contact your doctor immediately. They may advise adjusting the dosage or temporarily stopping the medication.
Q: Can UDIBID 300MG be taken with other medications?
UDIBID 300MG can interact with certain medications, such as antacids containing aluminium, cholesterol-lowering agents (e.g., cholestyramine, colestipol), and oral contraceptives. Always inform your doctor about all medications you are currently taking to avoid potential interactions.
Q: Is UDIBID 300MG safe during pregnancy?
The use of UDIBID 300MG during pregnancy requires careful consideration. It should only be used if the potential benefits outweigh the risks, and strictly under the guidance of a healthcare professional. Animal studies have shown some potential risks, and human data is limited.
Additional Information
UDIBID 300MG, containing Ursodeoxycholic Acid, stands as a vital medication in the management of various hepatobiliary disorders, particularly cholesterol gallstones and Primary Biliary Cholangitis. Its unique mechanism of action, involving the reduction of cholesterol secretion into bile and cytoprotective effects on liver cells, makes it an indispensable therapeutic option. Patients benefit from its ability to dissolve gallstones, improve bile flow, and mitigate liver damage, leading to enhanced liver function and overall quality of life. Adherence to the prescribed dosage and regular medical follow-ups are crucial for maximizing the efficacy and safety of UDIBID 300MG. While generally well-tolerated, awareness of potential side effects and interactions with other medications is important. Always consult your healthcare provider for personalized advice and to ensure this treatment aligns with your specific health needs, contributing to optimal liver health and well-being.