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Gastrointestinal
RABIZIT-L CAP
SALT COMPOSITION
RABIPRAZOLE+LEVOSULPRIDETYPE
CAPSULE
STORAGE
Store below 25°C in a cool, dry place, protected from direct sunlight and moisture. Keep out of reach of children.
PRODUCT INTRODUCTION
RABIZIT-L CAP is a highly effective medication designed to provide comprehensive relief from various gastrointestinal issues. This combination capsule, containing Rabeprazole and Levosulpride, is widely prescribed in India for managing conditions like gastroesophageal reflux disease (GERD), dyspepsia, and peptic ulcers. It works by reducing stomach acid production and enhancing gut motility, offering a dual approach to digestive health. RABIZIT-L CAP helps alleviate symptoms such as heartburn, acid regurgitation, bloating, and abdominal discomfort, improving overall patient comfort and quality of life.
Uses of RABIZIT-L CAP
RABIZIT-L CAP is indicated for the treatment of various gastrointestinal disorders that benefit from reduced stomach acid and improved gut motility.
- Gastroesophageal Reflux Disease (GERD)
RABIZIT-L CAP effectively treats GERD, a chronic condition where stomach acid flows back into the esophagus, causing heartburn, chest pain, and acid regurgitation. Rabeprazole reduces acid production, while Levosulpride enhances esophageal clearance and gastric emptying, providing significant relief and promoting healing of esophageal erosions.
- Dyspepsia (Indigestion)
This medication is highly beneficial for functional dyspepsia, characterized by symptoms like bloating, early satiety, epigastric pain, and discomfort without an identifiable organic cause. Levosulpride improves gastric motility and reduces visceral hypersensitivity, while Rabeprazole manages any associated acid-related symptoms, leading to improved digestive comfort.
- Peptic Ulcers
RABIZIT-L CAP aids in the healing and prevention of peptic ulcers (gastric and duodenal ulcers) by significantly reducing stomach acid. Lower acid levels create a more favorable environment for ulcer healing and protect the stomach lining from further damage. The prokinetic action also helps in reducing symptoms associated with ulcers.
Side Effects of RABIZIT-L CAP
Like all medications, RABIZIT-L CAP can cause side effects, though not everyone experiences them. Most side effects are mild and temporary.
Common side effects
- Nausea
- Vomiting
- Diarrhea
- Abdominal pain
- Headache
- Dizziness
- Flatulence
While less common, some serious side effects may occur. Seek immediate medical attention if you experience any of these.
- Allergic reactions (rash, itching, swelling)
- Liver problems (yellowing of skin/eyes)
- Severe diarrhea (Clostridium difficile-associated diarrhea)
- Bone fractures (with long-term use of PPIs)
If any side effect persists or worsens, or if you experience any unusual symptoms, consult your doctor promptly.
How to use RABIZIT-L CAP
- Adults:
Typically, one capsule once daily, preferably before breakfast, or as directed by a physician. The duration of treatment depends on the specific condition and patient response. It should be swallowed whole with water and not crushed or chewed.
- Children:
The safety and efficacy of RABIZIT-L CAP in pediatric patients have not been established. It is generally not recommended for use in children. Consult a pediatrician for alternative treatment options.
- Elderly:
No specific dose adjustment is usually required for elderly patients, but caution is advised, especially in those with pre-existing renal or hepatic impairment. Close monitoring for side effects is recommended.
- Missed Dose:
If you miss a dose, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.
How RABIZIT-L CAP works
RABIZIT-L CAP combines two powerful agents: Rabeprazole and Levosulpride, each with a distinct mechanism of action. Rabeprazole belongs to the class of proton pump inhibitors (PPIs). It works by irreversibly binding to the H+/K+-ATPase enzyme system, also known as the proton pump, located on the secretory surface of the parietal cells in the stomach. This action effectively blocks the final step in gastric acid secretion, leading to a significant and sustained reduction in stomach acid production. Levosulpride is a prokinetic agent and a selective dopamine D2 receptor antagonist. It acts primarily on the peripheral D2 receptors in the gastrointestinal tract, increasing the release of acetylcholine. Acetylcholine is a neurotransmitter that enhances the motility of the smooth muscles in the stomach and intestines. This leads to improved gastric emptying, reduced reflux, and relief from symptoms like nausea, vomiting, and bloating, complementing Rabeprazole's acid-reducing effects for comprehensive GI management.
Precautions
- Inform your doctor about all your medical conditions, especially liver or kidney disease.
- Avoid alcohol consumption as it may worsen stomach irritation and side effects.
- Long-term use of PPIs like Rabeprazole may increase the risk of bone fractures and magnesium deficiency.
- Do not stop taking the medication abruptly without consulting your doctor.
- Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding.
- This medication may mask symptoms of serious underlying conditions; proper diagnosis is essential.
Safety Advice
Alcohol
UNSAFEConsuming alcohol while taking RABIZIT-L CAP can increase the risk of stomach irritation and may exacerbate side effects like dizziness and nausea. It is advisable to avoid alcohol during treatment.
Pregnancy
CONSULT YOUR DOCTORRABIZIT-L CAP should be used during pregnancy only if clearly needed and after consulting your doctor. The potential benefits must outweigh the possible risks to the fetus.
Breastfeeding
CONSULT YOUR DOCTORIt is unknown whether components of RABIZIT-L CAP pass into breast milk. Consult your doctor before breastfeeding while on this medication to assess the risks and benefits.
Driving
CAUTIONRABIZIT-L CAP may cause dizziness or drowsiness in some individuals. If you experience these symptoms, avoid driving or operating heavy machinery until you feel well.
Kidney
CAUTIONPatients with severe kidney disease should use RABIZIT-L CAP with caution. Dose adjustments may be necessary, and regular monitoring of kidney function is recommended. Consult your doctor.
Liver
CAUTIONRABIZIT-L CAP should be used with caution in patients with liver impairment. Your doctor may adjust the dosage and monitor liver function tests regularly to ensure safety.
Fact Box
Frequently asked questions by patients
Q: Can RABIZIT-L CAP be taken with food?
A: It is generally recommended to take RABIZIT-L CAP on an empty stomach, preferably 30 minutes before breakfast. This ensures optimal absorption and effectiveness of Rabeprazole in reducing stomach acid.
Q: How long does it take for RABIZIT-L CAP to show its effect?
A: You may start feeling relief from symptoms within a few days of starting RABIZIT-L CAP. However, for complete healing of conditions like ulcers or severe GERD, it may take several weeks of consistent use as prescribed by your doctor.
Q: Is RABIZIT-L CAP safe for long-term use?
A: Long-term use of RABIZIT-L CAP, especially the PPI component, should be under medical supervision. Prolonged use may be associated with risks like bone fractures, magnesium deficiency, and increased risk of certain infections. Your doctor will assess the need for long-term therapy.
Q: What should I do if I experience severe diarrhea while taking this medicine?
A: If you experience severe or persistent diarrhea, especially if it's watery or bloody, while taking RABIZIT-L CAP, contact your doctor immediately. This could be a sign of a rare but serious infection (Clostridium difficile-associated diarrhea) that requires prompt medical attention.
Frequently Asked Questions
Q: What is RABIZIT-L CAP used for?
RABIZIT-L CAP is primarily used to treat gastrointestinal conditions such as Gastroesophageal Reflux Disease (GERD), dyspepsia (indigestion), and peptic ulcers. It helps reduce stomach acid and improve gut movement, alleviating symptoms like heartburn, bloating, and abdominal discomfort.
Q: How does RABIZIT-L CAP work?
This capsule contains Rabeprazole, a proton pump inhibitor that significantly reduces stomach acid production, and Levosulpride, a prokinetic agent that enhances the movement of food through the digestive tract. Together, they offer comprehensive relief from acid-related issues and motility disorders.
Q: Are there any dietary restrictions while taking RABIZIT-L CAP?
While there are no strict dietary restrictions, it is advisable to avoid foods and beverages that can trigger acid reflux or worsen indigestion, such as spicy foods, fatty meals, caffeine, and carbonated drinks. Eating smaller, frequent meals can also be beneficial.
Q: Can I take antacids along with RABIZIT-L CAP?
Generally, it's best to avoid taking antacids simultaneously with RABIZIT-L CAP. If you need immediate relief from heartburn, take antacids at least two hours apart from your RABIZIT-L CAP dose. Always consult your doctor for personalized advice.
Q: What are the common side effects of RABIZIT-L CAP?
Common side effects may include nausea, vomiting, diarrhea, abdominal pain, headache, and dizziness. These are usually mild and temporary. If any side effect persists or becomes bothersome, inform your doctor.
Additional Information
RABIZIT-L CAP stands as a reliable and effective therapeutic option for individuals grappling with various gastrointestinal discomforts in India. By combining the potent acid-suppressing action of Rabeprazole with the prokinetic benefits of Levosulpride, it offers a holistic approach to managing conditions like GERD, dyspepsia, and peptic ulcers. This dual-action formula not only provides rapid symptomatic relief from heartburn, acid regurgitation, and bloating but also aids in the healing of esophageal and gastric lesions, promoting long-term digestive health. Patients are encouraged to adhere strictly to their physician's dosage and administration instructions to maximize efficacy and minimize potential side effects. While generally well-tolerated, awareness of possible adverse reactions and precautions, especially concerning long-term use or co-existing conditions, is crucial. RABIZIT-L CAP empowers patients to regain comfort and improve their quality of life, making it a valuable addition to the Indian pharmaceutical landscape for gastrointestinal care.