PRODUCT INTRODUCTION

RABIZIT-DSR CAP A/A is a highly effective medication designed to provide comprehensive relief from various gastrointestinal issues. This capsule combines the power of Rabeprazole, a proton pump inhibitor (PPI), with Domperidone, a prokinetic agent. It is widely prescribed in India for conditions like gastroesophageal reflux disease (GERD), peptic ulcers, and dyspepsia, which often manifest as heartburn, acid reflux, nausea, and vomiting. By targeting both acid production and gastric motility, RABIZIT-DSR offers a dual approach to managing digestive discomfort, helping patients regain their quality of life. Always consult a healthcare professional for proper diagnosis and dosage.

Uses of RABIZIT-DSR CAP A/A

RABIZIT-DSR CAP A/A is primarily used to treat conditions associated with excessive stomach acid production and impaired gastrointestinal motility. It offers relief from a range of digestive discomforts.

  • Gastroesophageal Reflux Disease (GERD)

    RABIZIT-DSR is highly effective in treating GERD, a chronic condition where stomach acid flows back into the esophagus, causing heartburn, regurgitation, and potential damage to the esophageal lining. Rabeprazole reduces acid production, while Domperidone helps prevent reflux by improving esophageal sphincter tone and gastric emptying.

  • Peptic Ulcer Disease

    This medication is used to heal and prevent recurrence of peptic ulcers, which are sores that develop on the lining of the stomach, small intestine, or esophagus. Rabeprazole significantly reduces acid, allowing the ulcers to heal, while Domperidone helps manage associated symptoms like nausea and bloating, promoting overall digestive comfort.

  • Dyspepsia and Nausea/Vomiting

    RABIZIT-DSR provides relief from functional dyspepsia, characterized by persistent or recurrent pain or discomfort centered in the upper abdomen. Domperidone's anti-emetic properties effectively control nausea and vomiting often associated with dyspepsia, acid reflux, or other gastrointestinal disturbances, improving patient comfort and well-being.

Side Effects of RABIZIT-DSR CAP A/A

Like all medicines, RABIZIT-DSR CAP A/A can cause side effects, although not everybody gets them. Most side effects are mild and temporary. If any of these bother you or persist, please consult your doctor.

Common side effects

  • Headache
  • Diarrhea
  • Nausea
  • Abdominal pain
  • Dry mouth

Less common or rare side effects may occur and require immediate medical attention if experienced.

  • Bone fractures (with long-term use of Rabeprazole)
  • Irregular heartbeat (arrhythmia) due to Domperidone
  • Allergic reactions (rash, itching, swelling)

If you experience any severe or persistent side effects, or if you notice any other symptoms not listed here, please contact your doctor or pharmacist immediately for advice.

How to use RABIZIT-DSR CAP A/A

  • Adults:

    Typically, one RABIZIT-DSR CAP A/A capsule is taken once daily, preferably in the morning, 30 minutes before a meal. Swallow the capsule whole with water; do not crush or chew it. The duration of treatment will depend on the specific condition and your doctor's assessment. Follow your physician's instructions precisely.

  • Children:

    RABIZIT-DSR CAP A/A is generally not recommended for children due to limited safety and efficacy data. Pediatric use should only be considered under strict medical supervision and if deemed absolutely necessary by a specialist, with careful consideration of potential risks versus benefits.

  • Elderly:

    Elderly patients may be more susceptible to certain side effects, especially with Domperidone. While no specific dose adjustment is usually required for Rabeprazole, caution is advised. Your doctor may start with a lower dose or monitor you more closely for any adverse reactions, particularly concerning cardiac health.

  • Missed Dose:

    If you miss a dose of RABIZIT-DSR CAP A/A, take it as soon as you remember, provided it's not almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to compensate for a missed one.

How RABIZIT-DSR CAP A/A works

RABIZIT-DSR CAP A/A works through its two active ingredients: Rabeprazole and Domperidone. Rabeprazole belongs to the class of proton pump inhibitors (PPIs). It works by irreversibly binding to and inhibiting the H+/K+-ATPase enzyme system, commonly known as the proton pump, located in the parietal cells of the stomach. This inhibition effectively blocks the final step of acid secretion, leading to a significant and sustained reduction in gastric acid production. This action helps in healing acid-related damage to the esophagus and stomach lining. Domperidone, on the other hand, is a dopamine antagonist that acts as a prokinetic agent. It works by blocking dopamine receptors in the chemoreceptor trigger zone (CTZ) in the brain and in the gastrointestinal tract. This action increases the tone of the lower esophageal sphincter, enhances gastric emptying, and improves coordination of gastrointestinal contractions. By accelerating the movement of food through the stomach and intestines, Domperidone helps reduce symptoms like nausea, vomiting, bloating, and discomfort associated with slow gastric motility, thereby complementing Rabeprazole's acid-reducing effects.

Precautions

  • Inform your doctor if you have liver or kidney disease before starting treatment.
  • Avoid long-term use of this medication unless advised by your doctor, especially due to potential bone fracture risk with PPIs.
  • Patients with known heart conditions or a history of heart rhythm disorders should use Domperidone with caution.
  • This medicine may mask symptoms of serious underlying conditions, such as stomach cancer. Consult your doctor if symptoms persist.
  • Do not stop taking the medication abruptly without consulting your doctor, as it may lead to rebound acid production.
  • Inform your doctor about all other medications you are taking to avoid potential drug interactions.

Safety Advice

Alcohol

Alcohol

CAUTION

Consuming alcohol while taking RABIZIT-DSR CAP A/A may worsen symptoms of acidity and heartburn. It can also irritate the stomach lining, potentially counteracting the medication's benefits. It is advisable to limit or avoid alcohol intake.

Pregnancy

Pregnancy

CONSULT YOUR DOCTOR

There is limited data on the use of RABIZIT-DSR CAP A/A during pregnancy. It should only be used if the potential benefits outweigh the risks to the fetus. Always consult your doctor before taking this medication if you are pregnant or planning to conceive.

Breastfeeding

Breastfeeding

CONSULT YOUR DOCTOR

Both Rabeprazole and Domperidone can pass into breast milk. Therefore, RABIZIT-DSR CAP A/A is generally not recommended during breastfeeding. Discuss the risks and benefits with your doctor to make an informed decision.

Driving

Driving

CAUTION

RABIZIT-DSR CAP A/A may cause dizziness, drowsiness, or visual disturbances in some individuals. If you experience any of these symptoms, it is advisable to avoid driving or operating heavy machinery until you are sure you can perform such activities safely.

Kidney

Kidney

CAUTION

Patients with severe kidney impairment should use RABIZIT-DSR CAP A/A with caution. Dose adjustment may be necessary, especially for Domperidone. Your doctor will assess your kidney function and determine the appropriate dosage for you.

Liver

Liver

CAUTION

RABIZIT-DSR CAP A/A should be used with caution in patients with moderate to severe liver disease. The liver metabolizes both active ingredients, and impaired liver function can lead to increased drug levels. Your doctor may adjust the dosage or recommend alternative treatments.

Fact Box

Chemical Class
Benzimidazole (Rabeprazole), Benzimidazole derivative (Domperidone)
Habit Forming
No
Therapeutic Class
Anti-ulcerant, Prokinetic
Action Class
Acid secretion inhibitor, Gastric motility enhancer

Frequently asked questions by patients

Q: When is the best time to take RABIZIT-DSR CAP A/A?

A: It is generally recommended to take RABIZIT-DSR CAP A/A once daily in the morning, approximately 30 minutes before your first meal. This timing allows the medication to be most effective in reducing acid production throughout the day.

Q: How long should I continue taking this medicine?

A: The duration of treatment with RABIZIT-DSR CAP A/A depends on your specific condition and your doctor's assessment. Do not stop taking it without consulting your doctor, even if your symptoms improve, as premature discontinuation can lead to symptom recurrence.

Q: Can I take RABIZIT-DSR CAP A/A with other medications?

A: It's crucial to inform your doctor about all other medications, including over-the-counter drugs and herbal supplements, you are currently taking. RABIZIT-DSR can interact with certain medicines, potentially altering their effects or increasing side effects. Your doctor can advise on potential interactions.

Q: What if my symptoms do not improve after taking this capsule?

A: If your symptoms do not improve or worsen after a few days of taking RABIZIT-DSR CAP A/A as prescribed, you should consult your doctor. They may need to re-evaluate your condition, adjust your dosage, or consider alternative treatments.

Frequently Asked Questions

Q: Is RABIZIT-DSR CAP A/A suitable for long-term use?

Long-term use of RABIZIT-DSR, particularly the Rabeprazole component, should be carefully monitored by a doctor. Prolonged use of PPIs like Rabeprazole has been associated with increased risks of bone fractures, kidney problems, and magnesium deficiency. Your doctor will weigh the benefits against these potential risks and advise accordingly.

Q: Can RABIZIT-DSR CAP A/A cause weight gain?

Weight gain is not a commonly reported side effect of RABIZIT-DSR CAP A/A. However, some individuals might experience changes in appetite or other metabolic effects that could indirectly influence weight. If you are concerned about weight changes, discuss them with your healthcare provider.

Q: What dietary changes should I make while on this medication?

While taking RABIZIT-DSR CAP A/A, it is advisable to avoid foods and beverages that trigger acidity, such as spicy foods, fatty meals, citrus fruits, caffeine, and carbonated drinks. Eating smaller, more frequent meals and avoiding lying down immediately after eating can also help manage symptoms effectively.

Q: Does RABIZIT-DSR CAP A/A affect blood pressure?

Domperidone, one of the components, has been associated with rare cases of QT prolongation, which can affect heart rhythm and potentially blood pressure in susceptible individuals, especially at higher doses. Rabeprazole generally does not significantly affect blood pressure. If you have a history of heart issues, inform your doctor.

Q: Is it safe to take RABIZIT-DSR CAP A/A if I have diabetes?

Yes, RABIZIT-DSR CAP A/A can generally be taken by individuals with diabetes. Neither Rabeprazole nor Domperidone is known to directly affect blood sugar levels. However, it's always best to inform your doctor about your diabetic condition and all medications you are taking to ensure there are no potential interactions or specific precautions needed.

Additional Information

Category
Gastrointestinal
FORM
CAPSULE
Tag
Proton Pump Inhibitor (PPI), Prokinetic, Antacid, Anti-emetic
Packing
20x10
Composition
RABIPRAZOLE+DOMEPERIDONE CAP
Disclaimer: This information is provided for educational purposes only and should not replace professional medical advice. Always consult your healthcare provider before starting, stopping, or changing any medication. Individual results may vary. Keep this and all medications out of reach of children.

RABIZIT-DSR CAP A/A offers a powerful and effective solution for managing a range of gastrointestinal discomforts, from acid reflux and heartburn to nausea and vomiting. Its dual-action formula, combining the acid-reducing properties of Rabeprazole with the prokinetic effects of Domperidone, provides comprehensive relief and promotes digestive health. By addressing both excessive acid production and impaired gut motility, it helps patients regain comfort and improve their quality of life. It is crucial to remember that while RABIZIT-DSR is highly effective, it is a prescription medication and should be used strictly under the guidance of a healthcare professional. Adhering to the prescribed dosage and duration, along with lifestyle modifications, will maximize its benefits and minimize potential risks. Always consult your doctor for personalized medical advice and to ensure this medication is appropriate for your specific health needs.

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