PANITAS-DSR CAP

Uses of PANITAS-DSR CAP

PANITAS-DSR CAP is prescribed to treat various gastrointestinal conditions where both acid suppression and improved gut motility are required, offering relief from a range of digestive discomforts.

• Gastroesophageal Reflux Disease (GERD)

  Relieves symptoms like heartburn, regurgitation, and difficulty swallowing by reducing stomach acid and preventing reflux. It promotes healing of esophageal damage caused by acid and improves overall esophageal health, ensuring long-term relief from GERD symptoms.

• Peptic Ulcers

  Aids in the healing of gastric and duodenal ulcers by significantly lowering stomach acid levels, creating a favorable environment for ulcer repair and preventing recurrence. This helps in reducing pain and discomfort associated with ulcers, facilitating a faster recovery.

• Dyspepsia (Indigestion)

  Alleviates symptoms such as bloating, fullness, epigastric pain, and nausea associated with indigestion by regulating acid secretion and enhancing gastric emptying. It helps in restoring normal digestive function, providing comfort after meals.

Side Effects of PANITAS-DSR CAP

While PANITAS-DSR CAP is generally well-tolerated, some individuals may experience side effects. Most are mild and temporary, but consult your doctor if they persist or worsen.

Less commonly, more serious side effects can occur, requiring immediate medical attention. Be vigilant for any unusual or severe symptoms.

If you experience any severe or unusual side effects, stop taking the medication and seek urgent medical advice from your healthcare provider immediately.

How to use PANITAS-DSR CAP

• Adults:

  Typically, one PANITAS-DSR CAP once daily, preferably in the morning before breakfast, or as directed by a physician. The sustained-release formulation allows for convenient once-daily dosing, ensuring consistent therapeutic levels.

• Children:

  Not generally recommended for pediatric use unless specifically prescribed and monitored by a specialist due to limited safety data. Dosage, if prescribed, would be determined by a pediatrician based on weight, age, and specific medical condition.

• Elderly:

  No specific dosage adjustment is usually required, but caution should be exercised in elderly patients, especially those with impaired renal or hepatic function. Close monitoring for potential side effects and drug interactions is advisable.

• Missed Dose:

  If a dose is missed, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.

How PANITAS-DSR CAP works

Pantoprazole, a benzimidazole derivative, acts as a proton pump inhibitor. It irreversibly binds to the H+/K+-ATPase enzyme system (the proton pump) found on the secretory surface of parietal cells in the stomach. This action inhibits the final step in gastric acid production, significantly reducing both basal and stimulated acid secretion. This leads to a sustained decrease in stomach acid levels, allowing ulcers and erosions to heal and alleviating acid-related symptoms, thereby promoting a healthier gastric environment. Domperidone, on the other hand, is a dopamine D2 receptor antagonist with prokinetic properties. It works primarily on the upper gastrointestinal tract, increasing esophageal peristalsis and lower esophageal sphincter pressure, thereby preventing reflux. It also accelerates gastric emptying by enhancing antral and duodenal contractions, which helps in relieving symptoms like bloating, fullness, and indigestion. Furthermore, Domperidone has antiemetic properties, blocking dopamine receptors in the chemoreceptor trigger zone (CTZ) in the brain, thus effectively reducing nausea and vomiting.

Precautions

• Inform your doctor about all existing medical conditions, especially liver or kidney disease, heart problems (including history of prolonged QT interval), or osteoporosis.
• Avoid prolonged use of PPIs like Pantoprazole without medical supervision, as it may increase the risk of bone fractures, magnesium deficiency, and certain infections.
• Do not crush, chew, or break the sustained-release capsule; swallow it whole to ensure proper drug release and efficacy.
• Patients with a history of heart rhythm disorders or electrolyte imbalances should use Domperidone with extreme caution and under strict medical guidance.
• Report any symptoms of persistent diarrhea, fever, or severe abdominal pain immediately, as these could indicate a more serious condition.
• This medicine may mask symptoms of serious underlying conditions, such as gastric malignancy, so proper diagnosis before starting treatment is crucial.

Safety Advice

Alcohol

CAUTION

Consuming alcohol while on PANITAS-DSR CAP may worsen stomach irritation and increase the risk of side effects like dizziness. It's advisable to limit or avoid alcohol intake to ensure optimal treatment outcomes.

Pregnancy

CONSULT YOUR DOCTOR

The use of PANITAS-DSR CAP during pregnancy is generally not recommended unless clearly necessary and prescribed by a doctor after carefully assessing the potential benefits and risks. Limited data are available on its safety.

Breastfeeding

CONSULT YOUR DOCTOR

Domperidone is known to pass into breast milk in small amounts. Consult your doctor before using this medication while breastfeeding to weigh the potential risks to the infant against the maternal therapeutic benefits.

Driving

CAUTION

PANITAS-DSR CAP may cause dizziness or drowsiness in some individuals. If you experience these symptoms, avoid driving or operating heavy machinery until you are certain how the medication affects your alertness.

Kidney

CAUTION

Patients with severe kidney impairment should use PANITAS-DSR CAP with caution. Dosage adjustments may be necessary, and regular monitoring of kidney function is recommended by your doctor to prevent accumulation.

Liver

CAUTION

Use with caution in patients with moderate to severe liver disease. The metabolism of both components can be affected, potentially leading to increased drug levels. Your doctor will assess liver function and adjust dosage if needed.

Fact Box

Frequently asked questions by patients

Frequently Asked Questions

Additional Information