Pain Relievers
NIPTAS-S TAB
SALT COMPOSITION
NIMESULIDE 100+PCM 325 MG TABTYPE
TABLET
STORAGE
Store below 25°C in a cool, dry place, away from direct sunlight and moisture. Keep out of reach of children.
PRODUCT INTRODUCTION
NIPTAS-S TAB is a potent combination medication widely used in India for its analgesic, antipyretic, and anti-inflammatory properties. It contains Nimesulide (100 mg) and Paracetamol (325 mg), offering a synergistic approach to managing various painful and febrile conditions. This medication is particularly effective in alleviating symptoms associated with musculoskeletal pain, post-operative pain, dental pain, and fever. NIPTAS-S TAB helps patients regain comfort and improve their quality of life by targeting both pain and inflammation. Always consult a healthcare professional before starting this medication to ensure it is suitable for your specific condition and health profile.
Uses of NIPTAS-S TAB
NIPTAS-S TAB is prescribed for a variety of conditions requiring relief from pain, inflammation, and fever. It is commonly used for:
- Acute Pain Relief
Effectively manages various types of acute pain, including musculoskeletal pain, sprains, strains, and low back pain. The combination targets both the inflammatory component and the pain sensation, providing rapid and sustained relief.
- Fever (Pyrexia)
Reduces elevated body temperature associated with various infections or inflammatory conditions. Paracetamol's antipyretic action, combined with Nimesulide's anti-inflammatory effects, helps to quickly bring down fever and improve patient comfort.
- Post-operative and Dental Pain
Provides significant relief from pain and inflammation following surgical procedures or dental interventions. It helps in faster recovery by managing discomfort and swelling, allowing patients to resume normal activities more comfortably.
Side Effects of NIPTAS-S TAB
Like all medicines, NIPTAS-S TAB can cause side effects, although not everybody gets them. Most side effects are mild and temporary, but some can be serious. If you experience any persistent or severe side effects, seek immediate medical attention.
Common side effects
- Nausea
- Vomiting
- Diarrhea
- Stomach pain
- Heartburn
Less common or rare side effects may include more serious reactions. Contact your doctor immediately if you notice any of these:
- Liver damage (yellowing of skin/eyes)
- Kidney problems (changes in urine output)
- Allergic reactions (rash, itching, swelling)
- Gastrointestinal bleeding (black or tarry stools)
It is crucial to report any unusual symptoms to your doctor. Do not self-medicate or continue use if adverse reactions occur.
How to use NIPTAS-S TAB
- Adults:
Typically, one tablet twice daily after meals, or as directed by a physician. Do not exceed the prescribed dose or duration, usually not more than 7-10 days, due to potential liver and kidney risks.
- Children:
NIPTAS-S TAB is generally not recommended for children below 12 years of age due to the Nimesulide component. Pediatric dosing should be strictly determined by a pediatrician based on weight and condition, if considered absolutely necessary.
- Elderly:
Elderly patients may require a reduced dosage or closer monitoring due to potential age-related decline in liver and kidney function. Consult a doctor for appropriate dosage adjustments and to assess suitability.
- Missed Dose:
If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to compensate.
How NIPTAS-S TAB works
NIPTAS-S TAB works through the combined actions of its two active ingredients. Nimesulide is a non-steroidal anti-inflammatory drug (NSAID) that primarily inhibits cyclooxygenase-2 (COX-2) enzyme. By selectively blocking COX-2, Nimesulide reduces the production of prostaglandins, which are chemical mediators responsible for pain, inflammation, and fever. This selective action helps to minimize some of the gastrointestinal side effects associated with non-selective NSAIDs. Paracetamol, also known as Acetaminophen, is an analgesic and antipyretic. Its exact mechanism of action is not fully understood but is believed to involve the inhibition of prostaglandin synthesis predominantly in the central nervous system. This central action contributes significantly to its pain-relieving and fever-reducing effects, complementing the anti-inflammatory action of Nimesulide. Together, these two components provide comprehensive relief from pain, reduce inflammation, and bring down fever effectively.
Precautions
- Do not exceed the recommended dose or duration of treatment, especially due to the Nimesulide component's potential for hepatotoxicity.
- Use with caution in patients with a history of gastrointestinal ulcers, bleeding, or inflammatory bowel disease.
- Patients with pre-existing kidney or liver impairment should use this medication under strict medical supervision.
- Avoid concomitant use with other NSAIDs or Paracetamol-containing products to prevent overdose.
- Inform your doctor about all other medications, supplements, and herbal products you are taking to avoid potential drug interactions.
- Not recommended for use in the third trimester of pregnancy due to risks to the fetus.
Safety Advice
Alcohol
UNSAFEConsumption of alcohol while taking NIPTAS-S TAB is unsafe. It can significantly increase the risk of liver damage due to the presence of both Nimesulide and Paracetamol, which are metabolized in the liver.
Pregnancy
UNSAFENIPTAS-S TAB is generally considered unsafe during pregnancy, especially in the third trimester, as Nimesulide can harm the developing fetus and complicate delivery. Consult your doctor for safer alternatives.
Breastfeeding
CONSULT YOUR DOCTORThe components of NIPTAS-S TAB may pass into breast milk. It is advisable to consult your doctor before using this medication if you are breastfeeding to weigh the potential risks and benefits.
Driving
CAUTIONNIPTAS-S TAB may cause dizziness, drowsiness, or visual disturbances in some individuals. If you experience these symptoms, avoid driving or operating heavy machinery until you feel well.
Kidney
CONSULT YOUR DOCTORPatients with kidney disease should use NIPTAS-S TAB with extreme caution. Nimesulide can impair kidney function, especially in dehydrated or elderly patients. Dose adjustment or alternative medication may be necessary.
Liver
CONSULT YOUR DOCTORNIPTAS-S TAB should be used cautiously in patients with liver disease. Nimesulide carries a risk of hepatotoxicity, and Paracetamol overdose can also cause severe liver damage. Regular monitoring may be required.
Fact Box
Frequently asked questions by patients
Q: Can I take NIPTAS-S TAB on an empty stomach?
A: It is generally recommended to take NIPTAS-S TAB after meals to minimize the risk of gastrointestinal upset, which is a common side effect of NSAIDs like Nimesulide. Always follow your doctor's advice.
Q: Is NIPTAS-S TAB safe for long-term use?
A: NIPTAS-S TAB is typically prescribed for short-term relief of acute conditions. Long-term use is not recommended due to the potential for serious side effects, particularly affecting the liver and kidneys. Consult your doctor for prolonged pain management.
Q: What if I experience an allergic reaction?
A: If you experience symptoms of an allergic reaction such as rash, itching, swelling of the face/throat, severe dizziness, or trouble breathing, stop taking NIPTAS-S TAB immediately and seek urgent medical attention.
Q: Can NIPTAS-S TAB interact with other medications?
A: Yes, NIPTAS-S TAB can interact with blood thinners, other NSAIDs, certain blood pressure medications, and diuretics. Always inform your doctor about all medications you are currently taking to avoid adverse interactions.
Frequently Asked Questions
Q: What is NIPTAS-S TAB used for?
NIPTAS-S TAB is primarily used for relieving various types of pain, reducing inflammation, and bringing down fever. It is effective for conditions like musculoskeletal pain, post-operative pain, dental pain, and general fever.
Q: How quickly does NIPTAS-S TAB start working?
The effects of NIPTAS-S TAB typically begin within 30-60 minutes after administration. The combination of Nimesulide and Paracetamol ensures relatively quick onset of action for pain and fever relief.
Q: Can NIPTAS-S TAB cause stomach problems?
Yes, NIPTAS-S TAB, particularly due to its Nimesulide component (an NSAID), can cause gastrointestinal side effects such as nausea, vomiting, stomach pain, and heartburn. Taking it after food can help reduce these issues.
Q: Is a prescription required for NIPTAS-S TAB?
Yes, NIPTAS-S TAB is a prescription-only medication in India. It should only be taken under the guidance and supervision of a registered medical practitioner due to its potent ingredients and potential side effects.
Q: What should I do if I take more than the recommended dose?
If you suspect an overdose of NIPTAS-S TAB, seek immediate medical attention or contact a poison control center. Overdosing, especially on Paracetamol and Nimesulide, can lead to severe liver damage and other serious health complications.
Additional Information
NIPTAS-S TAB is a powerful combination medication offering effective relief from pain, inflammation, and fever, making it a valuable option for various acute conditions. Its dual-action formula, combining Nimesulide and Paracetamol, targets multiple pathways to provide comprehensive symptomatic relief. However, it is crucial to use NIPTAS-S TAB strictly as prescribed by a healthcare professional, adhering to the recommended dosage and duration. Awareness of potential side effects, especially concerning liver and kidney health, and careful consideration of precautions are paramount. Always inform your doctor about your complete medical history and any other medications to ensure safe and effective treatment. Prioritizing medical advice ensures optimal outcomes and minimizes risks associated with this potent medication.

