PRODUCT INTRODUCTION

COLDREF-PLUS TAB is a comprehensive medication designed to provide effective relief from common cold and allergy symptoms. This powerful combination of Cetirizine, Phenylephrine HCl, and Paracetamol targets multiple discomforts such as runny nose, sneezing, nasal congestion, fever, and body aches. Ideal for managing seasonal allergies and viral infections, COLDREF-PLUS TAB helps you feel better and resume your daily activities with ease. It's formulated to offer quick and sustained relief, making it a reliable choice for managing cold and flu symptoms in adults and children (as per physician's advice). Always consult a healthcare professional before use.

Uses of COLDREF-PLUS TAB

COLDREF-PLUS TAB is indicated for the effective relief of various symptoms associated with the common cold, flu, and allergic rhinitis.

  • Common Cold Symptoms

    Provides relief from a runny nose, sneezing, watery eyes, and nasal congestion often associated with the common cold. Its decongestant and antihistaminic properties work together to alleviate these bothersome symptoms, helping you breathe easier and feel more comfortable during a cold episode.

  • Allergic Rhinitis

    Effectively manages symptoms of allergic rhinitis, including sneezing, itching of the nose or throat, and watery eyes caused by allergens like pollen, dust mites, or pet dander. Cetirizine specifically targets the allergic response, offering significant relief from seasonal and perennial allergies.

  • Fever and Body Aches

    Reduces fever and alleviates mild to moderate pain such as headache, muscle aches, and general body discomfort that often accompany cold and flu infections. Paracetamol, a key component, acts as an antipyretic and analgesic, helping to bring down elevated body temperature and soothe pain.

Side Effects of COLDREF-PLUS TAB

Like all medications, COLDREF-PLUS TAB can cause side effects, although not everyone experiences them. Most side effects are mild and temporary.

Common side effects

  • Drowsiness
  • Dizziness
  • Dry mouth
  • Nausea
  • Headache
  • Insomnia
  • Nervousness

In rare cases, more serious side effects may occur. Seek immediate medical attention if you experience any of these.

  • Allergic reactions (rash, itching, swelling)
  • Increased blood pressure
  • Palpitations
  • Liver damage (with prolonged high doses of Paracetamol)
  • Difficulty urinating

If any side effect persists or worsens, or if you experience any unexpected symptoms, consult your doctor immediately. Do not discontinue the medication without medical advice.

How to use COLDREF-PLUS TAB

  • Adults:

    Typically, one tablet 2-3 times a day, or as directed by a physician. Do not exceed the recommended dose. Always follow your doctor's instructions carefully.

  • Children:

    Dosage should be strictly as prescribed by a pediatrician, based on age and weight. Self-medication in children is not advised. Always consult a doctor before administering to children.

  • Elderly:

    Use with caution and under medical supervision, as elderly patients may be more susceptible to side effects. A lower dose may be recommended by the doctor based on individual health conditions.

  • Missed Dose:

    If you miss a dose, take it as soon as you remember. If it's almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

How COLDREF-PLUS TAB works

COLDREF-PLUS TAB works through the synergistic action of its three active ingredients. Cetirizine, an antihistamine, blocks histamine H1 receptors, reducing allergic symptoms like runny nose, sneezing, and watery eyes. Phenylephrine HCl acts as a decongestant by constricting blood vessels in the nasal passages, thereby reducing swelling and congestion, making breathing easier. Paracetamol (PCM) is an analgesic and antipyretic; it works by inhibiting prostaglandin synthesis in the brain, which helps to reduce fever and alleviate pain such as headache and body aches associated with colds and flu. This triple-action formula effectively addresses the diverse symptoms of cold and flu, providing comprehensive relief. Cetirizine helps control allergic reactions, Phenylephrine clears nasal blockages, and Paracetamol tackles fever and pain, ensuring a broad spectrum of symptom management.

Precautions

  • Consult your doctor if you have pre-existing liver or kidney disease.
  • Use with caution in patients with high blood pressure, heart disease, or diabetes.
  • Avoid alcohol consumption while taking this medication as it can increase side effects.
  • May cause drowsiness; avoid driving or operating heavy machinery if affected.
  • Inform your doctor about all other medications, including herbal supplements, you are taking to avoid potential drug interactions.
  • Not recommended for use in children under 6 years without strict medical consultation.

Safety Advice

Alcohol

Alcohol

UNSAFE

Consumption of alcohol with COLDREF-PLUS TAB can increase the risk of drowsiness and dizziness, and may also enhance the risk of liver damage due to Paracetamol. It is advisable to avoid alcohol during treatment.

Pregnancy

Pregnancy

CONSULT YOUR DOCTOR

The use of COLDREF-PLUS TAB during pregnancy is generally not recommended unless clearly necessary and prescribed by a doctor. Consult your physician to assess the potential risks and benefits for both mother and baby.

Breastfeeding

Breastfeeding

CONSULT YOUR DOCTOR

Components of COLDREF-PLUS TAB may pass into breast milk and could potentially affect the nursing infant. It is advisable to consult your doctor before using this medication if you are breastfeeding to ensure infant safety.

Driving

Driving

CAUTION

COLDREF-PLUS TAB may cause drowsiness or dizziness in some individuals, which can impair your ability to drive or operate machinery safely. Exercise caution and avoid such activities if you feel drowsy or experience blurred vision.

Kidney

Kidney

CAUTION

Patients with pre-existing kidney conditions should use COLDREF-PLUS TAB with caution. Dose adjustments may be necessary, and regular monitoring is advised. Consult your doctor for personalized guidance before starting this medication.

Liver

Liver

CAUTION

COLDREF-PLUS TAB contains Paracetamol, which can cause liver damage in high doses or with prolonged use, especially in patients with liver impairment. Consult your doctor before use if you have liver disease or a history of liver issues.

Fact Box

Chemical Class
Antihistamine, Alpha-adrenergic agonist, Analgesic/Antipyretic
Habit Forming
No
Therapeutic Class
Cold & Cough Preparations / Antiallergics
Action Class
H1-receptor antagonist, Vasoconstrictor, Cyclooxygenase inhibitor

Frequently asked questions by patients

Q: Can COLDREF-PLUS TAB be taken on an empty stomach?

A: While COLDREF-PLUS TAB can generally be taken with or without food, taking it after meals may help reduce the chances of stomach upset, especially for individuals with a sensitive stomach. Always follow your doctor's advice regarding administration.

Q: How long can I take COLDREF-PLUS TAB?

A: COLDREF-PLUS TAB is typically used for short-term relief of cold and allergy symptoms. Do not use it for more than 7 days without consulting a doctor. Prolonged use without medical supervision is not recommended due to potential side effects.

Q: Is COLDREF-PLUS TAB safe for individuals with high blood pressure?

A: COLDREF-PLUS TAB contains Phenylephrine, a decongestant that can increase blood pressure. Individuals with high blood pressure should use this medication with extreme caution and only under a doctor's supervision. Your doctor will assess the risks and benefits.

Q: Will COLDREF-PLUS TAB make me drowsy?

A: Yes, Cetirizine, one of the components in COLDREF-PLUS TAB, can cause drowsiness or dizziness in some individuals, although it is considered less sedating than older antihistamines. It is advisable to avoid activities requiring mental alertness until you know how the medicine affects you.

Frequently Asked Questions

Q: What is COLDREF-PLUS TAB used for?

COLDREF-PLUS TAB is a combination medication used to relieve symptoms of the common cold, flu, and allergies. It helps alleviate a runny nose, sneezing, watery eyes, nasal congestion, fever, and body aches, providing comprehensive relief from multiple discomforts.

Q: How does COLDREF-PLUS TAB work?

This tablet works by combining three active ingredients: Cetirizine (an antihistamine) reduces allergy symptoms, Phenylephrine (a decongestant) clears nasal passages, and Paracetamol (an analgesic/antipyretic) reduces fever and pain. Together, they provide multi-symptom relief.

Q: Are there any specific dietary restrictions while taking this medicine?

Generally, there are no specific dietary restrictions. However, it's always good practice to maintain a balanced diet. Avoid alcohol consumption as it can increase side effects like drowsiness and may impact liver function due to Paracetamol.

Q: What should I do if I experience severe side effects?

If you experience severe side effects such as difficulty breathing, severe allergic reactions (rash, swelling), persistent high blood pressure, or signs of liver damage (yellowing of skin/eyes, dark urine), stop taking the medication and seek immediate medical attention.

Q: Can I take other cold medicines with COLDREF-PLUS TAB?

No, it is generally not recommended to take other cold or flu medications simultaneously with COLDREF-PLUS TAB, especially those containing similar ingredients like other antihistamines, decongestants, or paracetamol, to avoid overdose and increased side effects. Always consult your doctor or pharmacist.

Additional Information

Category
Respiratory
FORM
TABLET
Tag
Antihistamine, Decongestant, Analgesic, Antipyretic
Packing
20x10
Composition
CETRIZINE 5MG+PHENYLPHARINE HCL 10 MG+PCM 325
Disclaimer: This information is provided for educational purposes only and should not replace professional medical advice. Always consult your healthcare provider before starting, stopping, or changing any medication. Individual results may vary. Keep this and all medications out of reach of children.

COLDREF-PLUS TAB offers a robust solution for managing the uncomfortable symptoms of colds, flu, and allergies. Its triple-action formula effectively targets nasal congestion, runny nose, sneezing, fever, and body aches, allowing for quicker recovery and improved well-being. By combining an antihistamine, a decongestant, and an analgesic/antipyretic, it provides comprehensive relief, helping individuals to resume their daily activities with greater comfort. While generally effective, it is crucial to adhere to the prescribed dosage and duration, and to be aware of potential side effects and precautions, especially concerning liver and kidney health, and interactions with other medications or alcohol. Always consult a healthcare professional for personalized advice and to ensure this medication is appropriate for your specific health condition.

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