Antivirals
ACECLOBIR 400MG TAB
SALT COMPOSITION
ACYCLOVIR 400MGTYPE
TABLET
STORAGE
Store below 25°C in a cool, dry place, protected from light and moisture. Keep this and all medications out of reach of children.
PRODUCT INTRODUCTION
ACECLOBIR 400MG TABLET, containing Acyclovir 400mg, is a potent antiviral medication widely used in India to combat various viral infections. It effectively treats conditions caused by the herpes simplex virus, such as cold sores and genital herpes, as well as the varicella-zoster virus, responsible for chickenpox and shingles. This medication helps reduce the severity and duration of outbreaks, providing relief from painful symptoms and preventing complications. ACECLOBIR 400MG is a trusted choice for managing recurrent viral infections, improving patient quality of life and promoting faster recovery.
Uses of ACECLOBIR 400MG TAB
ACECLOBIR 400MG TABLET is prescribed for the treatment and prevention of various viral infections caused by herpes viruses.
- Herpes Simplex Virus Infections
This medication is highly effective in treating infections caused by the herpes simplex virus, including cold sores (oral herpes) and genital herpes. It helps to reduce the frequency, severity, and duration of outbreaks, alleviating symptoms like itching, pain, and blistering. Early treatment can prevent lesion development or speed healing, providing significant relief.
- Varicella-Zoster Virus Infections
ACECLOBIR 400MG is used to manage infections caused by the varicella-zoster virus, which includes chickenpox and shingles (herpes zoster). For chickenpox, it can reduce the severity and duration of the rash. In shingles, it helps to lessen pain, promote healing of lesions, and decrease the risk of post-herpetic neuralgia, improving patient comfort.
- Prevention of Recurrent Herpes
For individuals experiencing frequent or severe recurrences of genital herpes, ACECLOBIR 400MG can be prescribed as suppressive therapy. Taken regularly, it significantly reduces the number of future outbreaks, thereby improving quality of life and preventing potential transmission to partners. This prophylactic use helps maintain long-term viral control.
Side Effects of ACECLOBIR 400MG TAB
Like all medicines, ACECLOBIR 400MG TABLET can cause side effects, although not everybody gets them. Most side effects are mild and temporary and usually resolve on their own.
Common side effects
- Headache
- Nausea
- Vomiting
- Diarrhea
- Abdominal pain
Less commonly, some individuals may experience more serious side effects. If you notice any of these, seek immediate medical attention.
- Dizziness
- Fatigue
- Skin rash
- Kidney problems (e.g., acute renal failure)
- Neurological symptoms (e.g., confusion, hallucinations)
If any side effect bothers you or persists, please consult your doctor or pharmacist. Do not stop taking the medicine without medical advice.
How to use ACECLOBIR 400MG TAB
- Adults:
For herpes simplex, typically 200mg five times daily for 5-10 days, or 400mg three times daily for 5 days. For shingles, 800mg five times daily for 7 days. For chickenpox, 800mg four times daily for 5 days. Dosing varies based on condition and severity; always follow your physician's instructions precisely.
- Children:
For chickenpox, dosage is usually based on body weight, typically 20mg/kg (up to 800mg) four times daily for 5 days. For herpes simplex, 200mg four times daily for 5 days for children over 2 years. Consult a pediatrician for precise dosing and administration guidelines for children.
- Elderly:
Elderly patients may require a reduced dosage due to potential age-related decline in renal function. Close monitoring of kidney function is advised during treatment. Adequate hydration is important to prevent kidney issues. Your doctor will adjust the dose as necessary.
- Missed Dose:
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue your regular dosing schedule. Do not double the dose to catch up, as this can increase the risk of side effects.
How ACECLOBIR 400MG TAB works
Acyclovir, the active ingredient in ACECLOBIR 400MG TABLET, works by selectively inhibiting viral DNA synthesis. Once inside the infected cell, acyclovir is converted into its active triphosphate form by viral thymidine kinase. This active form then competes with deoxyguanosine triphosphate, a natural substrate, for incorporation into viral DNA by viral DNA polymerase. By incorporating into the viral DNA, acyclovir triphosphate acts as a chain terminator, preventing further elongation of the DNA strand. This selective action primarily affects virus-infected cells, as the initial phosphorylation step is largely dependent on viral enzymes, minimizing harm to healthy host cells. This targeted mechanism effectively halts viral replication, reducing the viral load and allowing the body's immune system to clear the infection more efficiently.
Precautions
- Inform your doctor if you have kidney problems, as dosage adjustment may be necessary to prevent accumulation.
- Maintain adequate hydration, especially during high-dose therapy, to prevent kidney issues and ensure proper drug elimination.
- This medication does not cure herpes but helps manage symptoms and reduce outbreaks; it does not eliminate the virus from the body.
- Avoid sexual activity during active genital herpes outbreaks to prevent transmission to partners.
- Use caution if operating machinery or driving, as dizziness or drowsiness may occur in some individuals.
- Complete the full course of treatment as prescribed by your doctor, even if symptoms improve, to ensure full efficacy and prevent recurrence.
Safety Advice
Alcohol
CAUTIONConsuming alcohol with ACECLOBIR 400MG TABLET may increase the risk of certain side effects like dizziness or stomach upset. It's advisable to limit alcohol intake during treatment and consult your doctor.
Pregnancy
CONSULT YOUR DOCTORAcyclovir is generally considered safe for use during pregnancy when clearly needed, with extensive data supporting its use. However, always consult your doctor to weigh the benefits against potential risks for you and your baby.
Breastfeeding
SAFE IF PRESCRIBEDAcyclovir passes into breast milk in small amounts, but it is generally considered safe for breastfeeding infants when used at therapeutic doses. Consult your doctor for personalized advice before use during lactation.
Driving
CAUTIONACECLOBIR 400MG TABLET may cause dizziness or drowsiness in some individuals. If you experience these symptoms, it is advisable to avoid driving or operating heavy machinery until you know how the medication affects you.
Kidney
CAUTIONUse with caution in patients with kidney disease. Dosage adjustments may be required based on renal function, and regular monitoring of kidney parameters is recommended. Ensure adequate hydration during treatment.
Liver
SAFE IF PRESCRIBEDACECLOBIR 400MG TABLET is generally safe for use in patients with liver disease, as it is primarily eliminated by the kidneys. However, consult your doctor for personalized advice, especially in cases of severe hepatic impairment.
Fact Box
Frequently asked questions by patients
Q: Can ACECLOBIR 400MG TABLET cure herpes?
A: No, ACECLOBIR 400MG TABLET does not cure herpes infections. It helps to manage the symptoms, reduce the frequency and severity of outbreaks, and speed up the healing process of lesions. It works by stopping the virus from multiplying within the body.
Q: How long does it take for ACECLOBIR 400MG TABLET to work?
A: You may start to notice improvement in your symptoms within 2-3 days of starting treatment. For best results, it is crucial to start the medication as soon as symptoms appear (e.g., tingling, itching) and complete the full course as prescribed by your doctor.
Q: Can I stop taking ACECLOBIR 400MG TABLET once my symptoms improve?
A: It is important to complete the full course of ACECLOBIR 400MG TABLET as prescribed by your doctor, even if your symptoms improve. Stopping early may lead to the infection returning or becoming more difficult to treat. Always follow your doctor's instructions for the full duration.
Q: What should I do if I forget to take a dose?
A: If you miss a dose of ACECLOBIR 400MG TABLET, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.
Frequently Asked Questions
Q: Is ACECLOBIR 400MG TABLET safe for long-term use?
For individuals with frequent recurrent herpes outbreaks, ACECLOBIR 400MG TABLET may be prescribed for long-term suppressive therapy. Your doctor will assess your condition and determine if long-term use is appropriate, monitoring for any potential side effects. Regular medical check-ups are recommended during prolonged treatment to ensure safety and efficacy.
Q: Can ACECLOBIR 400MG TABLET prevent the spread of herpes?
While ACECLOBIR 400MG TABLET can reduce the frequency and severity of outbreaks, it does not completely prevent the spread of herpes. It is still possible to transmit the virus, especially during active outbreaks. Always practice safe sex and avoid sexual contact during visible lesions to minimize transmission risk to partners.
Q: Are there any dietary restrictions while taking ACECLOBIR 400MG TABLET?
Generally, there are no specific dietary restrictions while taking ACECLOBIR 400MG TABLET. However, maintaining good hydration by drinking plenty of fluids is important, especially during treatment, to support kidney function and prevent potential side effects. Always consult your doctor for personalized dietary advice if you have concerns.
Q: What is the difference between cold sores and genital herpes?
Both cold sores and genital herpes are caused by the herpes simplex virus. Cold sores (oral herpes) typically appear around the mouth and are usually caused by HSV-1. Genital herpes affects the genital area and is more commonly caused by HSV-2, though HSV-1 can also cause it. ACECLOBIR 400MG TABLET is effective in treating both types of infections.
Q: Can ACECLOBIR 400MG TABLET be used for other viral infections?
ACECLOBIR 400MG TABLET is specifically effective against herpes viruses, including Herpes Simplex Virus (HSV) and Varicella-Zoster Virus (VZV). It is not effective against other types of viral infections like the common cold, influenza, or bacterial infections. Always use this medication only for the conditions it is prescribed for by your doctor.
Additional Information
ACECLOBIR 400MG TABLET, formulated with Acyclovir 400mg, stands as a crucial antiviral medication in the management of herpes simplex and varicella-zoster virus infections. It offers significant relief from the discomfort and pain associated with cold sores, genital herpes, chickenpox, and shingles by effectively inhibiting viral replication. This medication not only aids in the rapid healing of lesions but also plays a vital role in preventing recurrent outbreaks, thereby enhancing the overall quality of life for patients. As a prescription-only medication, it is imperative to adhere strictly to the dosage and duration recommended by a healthcare professional. While generally well-tolerated, awareness of potential side effects and necessary precautions, especially concerning kidney function and hydration, is important. ACECLOBIR 400MG TABLET represents a reliable therapeutic option, underlining the importance of timely medical consultation for appropriate diagnosis and treatment of viral conditions.